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NTIS 바로가기The journal of pain : official journal of the American Pain Society, v.12 no.2, 2011년, pp.185 - 193
Jansen, Jan-Peter (SZ Pain Center Berlin, Berlin, Germany) , Lorch, Daniel (Brandon Regional Hospital, Brandon, Florida) , Langan, John (Baillieston Health Centre, Glasgow, United Kingdom) , Lasko, Ben (Manna Research, Toronto, Canada) , Hermanns, Kai (Center of Pain Therapy Berlin, Prenzlauer Berg, Berlin, Germany) , Kleoudis, Christi S. (GlaxoSmithKline, Research Triangle Park, North Carolina) , Snidow, Jerry W. (GlaxoSmithKline, Research Triangle Park, North Carolina) , Pierce, Amy (GlaxoSmithKline, Research Triangle Park, North Carolina) , Wurzelmann, John (GlaxoSmithKline, Research Triangle Park, North Carolina) , Mortensen, Eric R. (GlaxoSmithKline, Research Triangle Park, North Carolina)
AbstractGastrointestinal (GI) side effects are common with opioid medication, and constipation affects ∼40% of patients. Such symptoms considerably impair patients' quality of life. Alvimopan is an orally administered, systemically available, peripherally acting mu-opioid receptor (PAM-OR) antag...
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