[논문]Gadobenate dimeglumine‐enhanced liver MR imaging in cirrhotic patients: Quantitative and qualitative comparison of 1‐hour and 3‐hour delayed images

Jeong, Woo Kyoung; Byun, Jae Ho; Lee, Seung Soo; Won, Hyung Jin; Kim, Kyoung Won; Shin, Yong Moon; Kim, Pyo Nyun; Lee, Moon‐; Gyu

doi:10.1002/jmri.22492

[해외논문] Gadobenate dimeglumine‐enhanced liver MR imaging in cirrhotic patients: Quantitative and qualitative comparison of 1‐hour and 3‐hour delayed images 원문보기

Journal of magnetic resonance imaging : JMRI, v.33 no.4, 2011년, pp.889 - 897

Jeong, Woo Kyoung (Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea) , Byun, Jae Ho (Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea) , Lee, Seung Soo (Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea) , Won, Hyung Jin (Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea) , Kim, Kyoung Won (Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea) , Shin, Yong Moon (Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea) , Kim, Pyo Nyun (Department of Radiology and Research Ins) , Lee, Moon‐Gyu

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AbstractPurpose:To compare the image quality and diagnostic performance of 1‐ and 3‐h delayed‐phase MR images (DPIs) after gadobenate dimeglumine injection in detecting small hepatocellular carcinomas (HCCs) in cirrhotic patients.Materials and Methods:Relative enhancement of the liver (REliver) and HCC (REHCC) and liver‐to‐lesion contrast‐to‐noise ratio (CNR) of HCC were measured quantitatively on 1‐ and 3‐h DPIs in 65 patients with 88 HCCs. For qualitative analysis, two radiologists independently evaluated three image sets in 19 patients with 25 HCCs ≤2 cm and in 16 controls without HCCs: conventional liver MR without DPI (set A), adding 1‐h DPI (set B), and adding 3‐h DPI (set C), using a 5‐point scale for diagnosing small HCCs. Diagnostic performance for small HCCs was analyzed using the alternative free‐response receiver operating characteristic method.Results:Mean REliver (P = 0.013) and REHCC (P < 0.001) were significantly higher on 1‐h than on 3‐h DPI, whereas CNR was significantly higher on 3‐h than on 1‐h DPI (P = 0.001). Observer‐averaged figure of merit (FOM) was significantly higher for set C than for set A (0.942 versus 0.883; P = 0.013).Conclusion:In cirrhotic patients, 3‐h DPI provides a higher liver‐to‐lesion contrast and a better diagnostic performance for small HCCs than 1‐h DPI. J. Magn. Reson. Imaging 2011;33:889–897. © 2011 Wiley‐Liss, Inc.

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[해외논문] Gadobenate dimeglumine‐enhanced liver MR imaging in cirrhotic patients: Quantitative and qualitative comparison of 1‐hour and 3‐hour delayed images 원문보기

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