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Antinociceptive effect of Brazilian armed spider venom toxin Tx3-3 in animal models of neuropathic pain

Pain, v.152 no.10, 2011년, pp.2224 - 2232  

Dalmolin, Gerusa Duarte (Programa de Pó) ,  Silva, Cássia Regina (s-graduaç) ,  Rigo, Flávia Karine (ã) ,  Gomes, Guilherme Monteiro (o em Farmacologia Bioquí) ,  Cordeiro, Marta do Nascimento (mica e Molecular, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil) ,  Richardson, Michael (Programa de Pó) ,  Silva, Marco Aurélio Romano (s-graduaç) ,  Prado, Marco Antonio Máximo (ã) ,  Gomez, Marcus Vinicius (o em Ciê) ,  Ferreira, Juliano (ncias Bioló)

Abstract AI-Helper 아이콘AI-Helper

AbstractVenoms peptides have produced exceptional sources for drug development to treat pain. In this study we examined the antinociceptive and side effects of Tx3-3, a peptide toxin isolated from Phoneutria nigriventer venom, which inhibits high-voltage-dependent calcium channels (VDCC), preferenti...

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