[논문]Factors influencing the physicochemical characteristics of cationic polymer-coated liposomes prepared by high-pressure homogenization

Chung, S.K.; Shin, G.H.; Jung, M.K.; Hwang, I.C.; Park, H.J.

doi:10.1016/j.colsurfa.2014.03.095

Factors influencing the physicochemical characteristics of cationic polymer-coated liposomes prepared by high-pressure homogenization

Colloids and surfaces. A, Physicochemical and engineering aspects, v.454, 2014년, pp.8 - 15

Chung, S.K. , Shin, G.H. , Jung, M.K. , Hwang, I.C. , Park, H.J.

Abstract ▼ AI-Helper

Nano-liposomes were prepared by the modified reverse phase evaporation method using high-speed and high-pressure homogenizers. The optimal conditions for preparation of non-coated liposome, chitosan-coated liposome, and eudragit EPO-coated liposome were investigated. The liposomal membrane was composed of soybean lecithin. Chitosan and eudragit EPO coated the external surface of liposomes by electrostatic interaction. The results show that the physicochemical properties (e.g., mean size, polydispersity index, surface charge, and encapsulation efficiency) of non-coated liposomes were affected by homogenization pressure, number of homogenizing cycles, and ratio of core material to lecithin. Chitosan coating increased the mean size of liposome. In the case of eudragit EPO coating, the mean size of liposome increased up to 0.2%; a further increase in the eudragit EPO concentration led to some changes of the mean size of eudragit EPO-coated liposome. The highest stability for 30 day was achieved with 0.3% chitosan-coated liposome and 0.3% eudragit EPO-coated liposome, respectively. The release property was influenced by the type of coating material; the chitosan and eudragit EPO coating layers on the non-coated liposome surface delayed the release of the core material. Overall, a core material to lecithin ratio of 1:3 and three homogenizing cycles under 1000bar were selected as the optimal processing conditions. In addition, 0.3% eudragit EPO-coated liposome was selected as the optimal coating.

주제어

참고문헌 (26)

Drug Dev. Ind. Pharm. Kamiya 35 1022 2009 10.1080/03639040802698786 Preparation of griseofulvin nanoparticle suspension by high-pressure homogenization and preservation of the suspension with saccharides and sugar alcohols

상세보기
J. Microencapsul. Liu 26 235 2009 10.1080/02652040802273469 Chitosan-coated nanoliposome as vitamin E carrier

상세보기
Drug Dev. Ind. Pharm. Villasmil-Sanchez 36 666 2010 10.3109/03639040903419640 Positively and negatively charged liposomes as carriers for transdermal delivery of sumatriptan: in vitro characterization

상세보기
Drug Deliv. Wang 18 208 2011 10.3109/10717544.2010.549526 Chitosan-coated liposomes for intracellular oligonucleotides delivery: characteristics and cell uptake behavior

상세보기
Colloids Surf. A Shi 396 122 2012 10.1016/j.colsurfa.2011.12.053 Nanoparticles as delivery vehicles for sunscreen agents

상세보기
Colloids Surf. A Tu 436 854 2013 10.1016/j.colsurfa.2013.08.019 Synthesis of poly(ethylene glycol) and poly(vinyl pyrrolidone)co-coated superparamagnetic iron oxide nanoparticle as a pH-sensitive release drug carrier

상세보기
Expert Opin. Drug Deliv. Fang 9 657 2012 10.1517/17425247.2012.679927 Nanoparticles as delivery carriers for anticancer prodrugs

상세보기
Nanoscale Res. Lett. Akbarzadeh 8 102 2013 10.1186/1556-276X-8-102 Liposome: classification, preparation, and applications

상세보기
Int. J. Pharm. Chem. Sci. Tikshdeep 1 754 2012 Liposome drug delivery: a review
J. Food Sci. Laye 73 N7 2008 10.1111/j.1750-3841.2008.00747.x Formation of biopolymer-coated liposomes by electrostatic deposition of chitosan

상세보기
Eur. J. Pharm. Biopharm. Hasanovic 75 148 2010 10.1016/j.ejpb.2010.03.014 Improvement in physicochemical parameters of DPPC liposomes and increase in skin permeation of aciclovir and minoxidil by the addition of cationic polymers

상세보기
Adv. Drug Deliv. Rev. Felber 64 979 2012 10.1016/j.addr.2011.09.006 pH-sensitive vesicles, polymeric micelles, and nanospheres prepared with polycarboxylates

상세보기
Food Hydrocoll. Chun 30 249 2013 10.1016/j.foodhyd.2012.05.024 Formation and stability of multiple-layered liposomes by layer-by-layer electrostatic deposition of biopolymers

상세보기
Colloids Surf. A Zhou 395 225 2012 10.1016/j.colsurfa.2011.12.034 Characteristics, phase behavior and control release for copolymer-liposome with both pH and temperature sensitivities

상세보기
Colloids Surf. A Liu 395 131 2012 10.1016/j.colsurfa.2011.12.017 Preparation, characterization and properties of liposome-loaded polycaprolactone microspheres as a drug delivery system

상세보기
J. Microencapsul. Bang 26 722 2009 10.3109/02652040902726994 Formation of size-controlled nano carrier systems by self-assembly

상세보기
Curr. Drug Deliv. Samad 4 297 2007 10.2174/156720107782151269 Liposomal drug delivery systems: an update review

상세보기
Biotechnol. Annu. Rev. Brandl 7 59 2001 10.1016/S1387-2656(01)07033-8 Liposomes as drug carriers: a technological approach
Int. J. Pharm. Barnadas-Rodriguez 213 175 2001 10.1016/S0378-5173(00)00661-X Factors involved in the production of liposomes with a high-pressure homogenizer

상세보기
Biochim. Biophys. Acta Mayhew 775 169 1984 10.1016/0005-2736(84)90167-6 Characterization of liposomes prepared using a microemulsifier

상세보기
J. Photochem. Photobiol. B Nguyen 125 194 2013 10.1016/j.jphotobiol.2013.06.009 Enhanced photoprotection for photo-labile compounds using double-layer coated corn oil-nanoemulsions with chitosan and lignosulfonate

상세보기
Analyst McIlwee 133 673 2008 10.1039/b717736d Thin chitosan films as a platform for SPR sensing of ferric ions

상세보기
J. Liposome Res. Cansell 11 229 2001 10.1081/LPR-100108464 Stability of marine lipid based liposomes under acid conditions. Influence of xanthan gum

상세보기
Colloids Surf. B Nacka 20 257 2001 10.1016/S0927-7765(00)00205-8 Physical and chemical stability of marine lipid-based liposomes under acid conditions

상세보기
J. Microencapsul. Bang 28 595 2011 10.3109/02652048.2011.557748 Influence of chitosan coating on the liposomal surface on physicochemical properties and the release profile of nanocarrier systems

상세보기
Soft Matter Cuomo 8 4415 2012 10.1039/c2sm07388a pH-responsive liposome-templated polyelectrolyte nanocapsules

상세보기

LOADING...

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관 관리번호, 논문명, 대등논문명, 저자 , 저널/프로시딩명, 발행기관, 발행년, 발행언어, 권, 호, 시작페이지, 끝페이지, ISBN, ISSN, 주제분야, 키워드, 초록(한글), 초록(영문), 저자(소속기관)
저장형식	Text(ASCII format) Excel format RefWorks Direct Export RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증

Factors influencing the physicochemical characteristics of cationic polymer-coated liposomes prepared by high-pressure homogenization

Abstract ▼ AI-Helper

주제어

참고문헌 (26)

이 논문을 인용한 문헌

연구과제 타임라인

관련 콘텐츠

원문 URL 링크

이 논문과 함께 이용한 콘텐츠

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트

연합인증

Factors influencing the physicochemical characteristics of cationic polymer-coated liposomes prepared by high-pressure homogenization

Abstract ▼ AI-Helper

주제어

참고문헌 (26)

이 논문을 인용한 문헌

연구과제 타임라인

전체(0) 논문(0) 특허(0) 보고서(0)

전체(0) 논문(0) 특허(0) 보고서(0)

관련 콘텐츠

원문 URL 링크

이 논문과 함께 이용한 콘텐츠

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트