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NTIS 바로가기Cell death & disease, v.5, 2014년, pp.e1292 -
Kim, H-J (Center for Metabolic Function Regulation, Department of Microbiology, Wonkwang University School of Medicine , Jeonbuk, Republic of Korea) , Oh, G-S (Center for Metabolic Function Regulation, Department of Microbiology, Wonkwang University School of Medicine , Jeonbuk, Republic of Korea) , Shen, A (Center for Metabolic Function Regulation, Department of Microbiology, Wonkwang University School of Medicine , Jeonbuk, Republic of Korea) , Lee, S-B (Center for Metabolic Function Regulation, Department of Microbiology, Wonkwang University School of Medicine , Jeonbuk, Republic of Korea) , Choe, S-K (Center for Metabolic Function Regulation, Department of Microbiology, Wonkwang University School of Medicine , Jeonbuk, Republic of Korea) , Kwon, K-B (Center for Metabolic Function Regulation, Department of Microbiology, Wonkwang University School of Medicine ,) , Lee, S , Seo, K-S , Kwak, T H , Park, R , So, H-S
Cisplatin (cis-diaminedichloroplatinum-II) is an extensively used chemotherapeutic agent, and one of its most adverse effects is ototoxicity. A number of studies have demonstrated that these effects are related to oxidative stress and DNA damage. However, the precise mechanism underlying cisplatin-a...
1Wang D, Lippard SJ. Cellular processing of platinum anticancer drugs . Nat Rev Drug Discov 2005 ; 4 : 307 –320. 15789122
2Rybak LP, Somani S. Ototoxicity Amelioration by protective agents. Ann N Y Acad Sci 1999 ; 884 : 143 –151. 10842591
3Deavall DG, Martin EA, Horner JM, Roberts R. Drug-induced oxidative stress and toxicity . J Toxicol 2012 ; 2012 : 645460 . 22919381
4Pabla N, Dong Z. Cisplatin nephrotoxicity: mechanisms and renoprotective strategies . Kidney Int 2008 ; 73 : 994 –1007. 18272962
5Kim HJ, Lee JH, Kim SJ, Oh GS, Moon HD, Kwon KB et al. Roles of NADPH oxidases in cisplatin-induced reactive oxygen species generation and ototoxicity . J Neurosci 2010 ; 30 : 3933 –3946. 20237264
6Jiang M, Yi X, Hsu S, Wang CY, Dong Z. Role of p53 in cisplatin-induced tubular cell apoptosis: dependence on p53 transcriptional activity . Am J Physiol Renal Physiol 2004 ; 287 : F1140 –F1147. 15315938
7So H, Kim H, Lee JH, Park C, Kim Y, Kim E et al. Cisplatin cytotoxicity of auditory cells requires secretions of proinflammatory cytokines via activation of ERK and NF-kappaB . J Assoc Res Otolaryngol 2007 ; 8 : 338 –355. 17516123
8Kim DH, Jung YJ, Lee JE, Lee AS, Kang KP, Lee S et al. SIRT1 activation by resveratrol ameliorates cisplatin-induced renal injury through deacetylation of p53 . Am J Physiol Renal Physiol 2011 ; 301 : F427 –F435. 21593185
9Oh GS, Kim HJ, Choi JH, Shen A, Choe SK, Karna A et al. Pharmacological activation of NQO1 increases NAD levels and attenuates cisplatin-mediated acute kidney injury in mice . Kidney Int 2014 ; 85 : 547 –560. 24025646
10Oka S, Hsu CP, Sadoshima J. Regulation of cell survival and death by pyridine nucleotides . Circ Res 2012 ; 111 : 611 –627. 22904041
11Abdellatif M. Sirtuins and pyridine nucleotides . Circ Res 2012 ; 111 : 642 –656. 22904043
12Imai S, Kiess W. Therapeutic potential of SIRT1 and NAMPT-mediated NAD biosynthesis in type 2 diabetes . Front Biosci (Landmark Ed) 2009 ; 14 : 2983 –2995. 19273250
13Belenky P, Bogan KL, Brenner C. NAD+ metabolism in health and disease . Trends Biochem Sci 2007 ; 32 : 12 –19. 17161604
14Fulco M, Cen Y, Zhao P, Hoffman EP, McBurney MW, Sauve AA et al. Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt . Dev Cell 2008 ; 14 : 661 –673. 18477450
15Kim D, Nguyen MD, Dobbin MM, Fischer A, Sananbenesi F, Rodgers JT et al. SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis . EMBO J 2007 ; 26 : 3169 –3179. 17581637
16Michan S, Sinclair D. Sirtuins in mammals: insights into their biological function . Biochem J 2007 ; 404 : 1 –13. 17447894
17Motta MC, Divecha N, Lemieux M, Kamel C, Chen D, Gu W et al. Mammalian SIRT1 represses forkhead transcription factors . Cell 2004 ; 116 : 551 –563. 14980222
18Vaziri H, Dessain SK, Ng Eaton E, Imai SI, Frye RA, Pandita TK et al. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase . Cell 2001 ; 107 : 149 –159. 11672523
19Yeung F, Hoberg JE, Ramsey CS, Keller MD, Jones DR, Frye RA et al. Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase . EMBO J 2004 ; 23 : 2369 –2380. 15152190
20Pillai JB, Isbatan A, Imai S, Gupta MP. Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2alpha deacetylase activity . J Biol Chem 2005 ; 280 : 43121 –43130. 16207712
21Virag L, Szabo C. The therapeutic potential of poly(ADP-ribose) polymerase inhibitors . Pharmacol Rev 2002 ; 54 : 375 –429. 12223530
22Mukhopadhyay P, Horvath B, Kechrid M, Tanchian G, Rajesh M, Naura AS et al. Poly(ADP-ribose) polymerase-1 is a key mediator of cisplatin-induced kidney inflammation and injury . Free Radic Biol Med 2011 ; 51 : 1774 –1788. 21884784
23Shino Y, Itoh Y, Kubota T, Yano T, Sendo T, Oishi R. Role of poly(ADP-ribose)polymerase in cisplatin-induced injury in LLC-PK1 cells . Free Radic Biol Med 2003 ; 35 : 966 –977. 14556861
24Ross D, Kepa JK, Winski SL, Beall HD, Anwar A, Siegel D. NAD(P)H:quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms . Chem Biol Interact 2000 ; 129 : 77 –97. 11154736
25Gaikwad A, Long DJII, Stringer JL, Jaiswal AK. In vivo role of NAD(P)H:quinone oxidoreductase 1 (NQO1) in the regulation of intracellular redox state and accumulation of abdominal adipose tissue . J Biol Chem 2001 ; 276 : 22559 –22564. 11309386
26Pazdro R, Burgess JR. The antioxidant 3H-1,2-dithiole-3-thione potentiates advanced glycation end-product-induced oxidative stress in SH-SY5Y cells . Exp Diabetes Res 2012 ; 2012 : 137607 . 22675339
27Jones CIIII, Zhu H, Martin SF, Han Z, Li Y, Alevriadou BR. Regulation of antioxidants and phase 2 enzymes by shear-induced reactive oxygen species in endothelial cells . Ann Biomed Eng 2007 ; 35 : 683 –693. 17340195
28Moscovitz O, Tsvetkov P, Hazan N, Michaelevski I, Keisar H, Ben-Nissan G et al. A mutually inhibitory feedback loop between the 20S proteasome and its regulator . NQO1. Mol Cell 2012 ; 47 : 76 –86. 22793692
29Haefeli RH, Erb M, Gemperli AC, Robay D, Courdier Fruh I, Anklin C et al. NQO1-dependent redox cycling of idebenone: effects on cellular redox potential and energy levels . PLoS One 2011 ; 6 : e17963 . 21483849
30Huang X, Dong Y, Bey EA, Kilgore JA, Bair JS, Li LS et al. An NQO1 substrate with potent antitumor activity that selectively kills by PARP1-induced programmed necrosis . Cancer Res 2012 ; 72 : 3038 –3047. 22532167
31Pardee AB, Li YZ, Li CJ. Cancer therapy with beta-lapachone . Curr Cancer Drug Targets 2002 ; 2 : 227 –242. 12188909
32Li LS, Bey EA, Dong Y, Meng J, Patra B, Yan J et al. Modulating endogenous NQO1 levels identifies key regulatory mechanisms of action of beta-lapachone for pancreatic cancer therapy . Clin Cancer Res 2011 ; 17 : 275 –285. 21224367
33Planchon SM, Wuerzberger S, Frydman B, Witiak DT, Hutson P, Church DR et al. Beta-lapachone-mediated apoptosis in human promyelocytic leukemia (HL-60) and human prostate cancer cells: a p53-independent response . Cancer Res 1995 ; 55 : 3706 –3711. 7641180
34Hwang JH, Kim DW, Jo EJ, Kim YK, Jo YS, Park JH et al. Pharmacological stimulation of NADH oxidation ameliorates obesity and related phenotypes in mice . Diabetes 2009 ; 58 : 965 –974. 19136651
35Kim SY, Jeoung NH, Oh CJ, Choi YK, Lee HJ, Kim HJ et al. Activation of NAD(P)H:quinone oxidoreductase 1 prevents arterial restenosis by suppressing vascular smooth muscle cell proliferation . Circ Res 2009 ; 104 : 842 –850. 19229058
36Kim YH, Hwang JH, Noh JR, Gang GT, Kim do H, Son HY et al. Activation of NAD(P)H:quinone oxidoreductase ameliorates spontaneous hypertension in an animal model via modulation of eNOS activity . Cardiovasc Res 2011 ; 91 : 519 –527. 21502369
37Kim YH, Hwang JH, Noh JR, Gang GT, Tadi S, Yim YH et al. Prevention of salt-induced renal injury by activation of NAD(P)H:quinone oxidoreductase 1, associated with NADPH oxidase. Free . Radic Biol Med 2012 ; 52 : 880 –888.
38Lee JS, Park AH, Lee SH, Lee SH, Kim JH, Yang SJ et al. Beta-lapachone, a modulator of NAD metabolism, prevents health declines in aged mice . PLoS One 2012 ; 7 : e47122 . 23071729
39David KK, Andrabi SA, Dawson TM, Dawson VL. Parthanatos, a messenger of death . Front Biosci (Landmark Ed) 2009 ; 14 : 1116 –1128. 19273119
40Hermeking H. The miR-34 family in cancer and apoptosis . Cell Death Differ 2010 ; 17 : 193 –199. 19461653
41Yamakuchi M, Ferlito M, Lowenstein CJ. miR-34a repression of SIRT1 regulates apoptosis . Proc Natl Acad Sci USA 2008 ; 105 : 13421 –13426. 18755897
42de Jongh FE, van Veen RN, Veltman SJ, de Wit R, van der Burg ME, van den Bent MJ et al. Weekly high-dose cisplatin is a feasible treatment option: analysis on prognostic factors for toxicity in 400 patients . Br J Cancer 2003 ; 88 : 1199 –1206. 12698184
43Bokemeyer C, Berger CC, Hartmann JT, Kollmannsberger C, Schmoll HJ, Kuczyk MA et al. Analysis of risk factors for cisplatin-induced ototoxicity in patients with testicular cancer . Br J Cancer 1998 ; 77 : 1355 –1362. 9579846
44Knight KR, Kraemer DF, Neuwelt EA. Ototoxicity in children receiving platinum chemotherapy: underestimating a commonly occurring toxicity that may influence academic and social development . J Clin Oncol 2005 ; 23 : 8588 –8596. 16314621
45Krishnakumar R, Kraus WL. The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets . Mol Cell 2010 ; 39 : 8 –24. 20603072
46Goodwin PM, Lewis PJ, Davies MI, Skidmore CJ, Shall S. The effect of gamma radiation and neocarzinostatin on NAD and ATP levels in mouse leukaemia cells . Biochim Biophys Acta 1978 ; 543 : 576 –582. 214144
47Skidmore CJ, Davies MI, Goodwin PM, Halldorsson H, Lewis PJ, Shall S et al. The involvement of poly(ADP-ribose) polymerase in the degradation of NAD caused by gamma-radiation and N-methyl-N-nitrosourea . Eur J Biochem 1979 ; 101 : 135 –142. 228934
48Canto C, Auwerx J. NAD+ as a signaling molecule modulating metabolism . Cold Spring Harb Symp Quant Biol 2012 ; 76 : 291 –298.
49Hasegawa K, Wakino S, Yoshioka K, Tatematsu S, Hara Y, Minakuchi H et al. Kidney-specific overexpression of Sirt1 protects against acute kidney injury by retaining peroxisome function . J Biol Chem 2010 ; 285 : 13045 –13056. 20139070
50Revollo JR, Li X. The ways and means that fine tune Sirt1 activity . Trends Biochem Sci 2013 ; 38 : 160 –167. 23394938
51Molitoris BA, Dagher PC, Sandoval RM, Campos SB, Ashush H, Fridman E et al. siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury . J Am Soc Nephrol 2009 ; 20 : 1754 –1764. 19470675
52Kruse JP, Gu W. Modes of p53 regulation . Cell 2009 ; 137 : 609 –622. 19450511
53Tang Y, Zhao W, Chen Y, Zhao Y, Gu W. Acetylation is indispensable for p53 activation . Cell 2008 ; 133 : 612 –626. 18485870
54Luo J, Nikolaev AY, Imai S, Chen D, Su F, Shiloh A et al. Negative control of p53 by Sir2alpha promotes cell survival under stress . Cell 2001 ; 107 : 137 –148. 11672522
55Brooks CL, Gu W. The impact of acetylation and deacetylation on the p53 pathway . Protein Cell 2011 ; 2 : 456 –462. 21748595
56Neumann M, Naumann M. Beyond IkappaBs: alternative regulation of NF-kappaB activity . FASEB J 2007 ; 21 : 2642 –2654. 17431096
57Yoshizaki T, Milne JC, Imamura T, Schenk S, Sonoda N, Babendure JL et al. SIRT1 exerts anti-inflammatory effects and improves insulin sensitivity in adipocytes . Mol Cell Biol 2009 ; 29 : 1363 –1374. 19103747
58Chen LF, Greene WC. Regulation of distinct biological activities of the NF-kappaB transcription factor complex by acetylation . J Mol Med (Berl) 2003 ; 81 : 549 –557. 12920522
59Jung YJ, Lee JE, Lee AS, Kang KP, Lee S, Park SK et al. SIRT1 overexpression decreases cisplatin-induced acetylation of NF-kappaB p65 subunit and cytotoxicity in renal proximal tubule cells . Biochem Biophys Res Commun 2012 ; 419 : 206 –210. 22330808
60Gang GT, Kim YH, Noh JR, Kim KS, Jung JY, Shong M et al. Protective role of NAD(P)H:quinone oxidoreductase 1 (NQO1) in cisplatin-induced nephrotoxicity . Toxicol Lett 2013 ; 221 : 165 –175. 23831944
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