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Genotoxic potential and in vitro tumour-promoting potential of 2-dodecylcyclobutanone and 2-tetradecylcyclobutanone, two radiolytic products of fatty acids

Mutation research. Genetic toxicology and environmental mutagenesis, v.770, 2014년, pp.95 - 104  

Yamakage, K. ,  Sui, H. ,  Ohta, R. ,  Toyoizumi, T. ,  Kawakami, K. ,  Matsumoto, H. ,  Takahashi, T. ,  Sasaki, K. ,  Ikezumi, M. ,  Negishi, S. ,  Izumi, K. ,  Todoriki, S. ,  Takashi, K. ,  Furuta, M.

Abstract AI-Helper 아이콘AI-Helper

The DNA-damaging and tumour-promoting effects of two 2-alkylcyclobutanones (2-ACBs), which are found in irradiated fat-containing foods, were investigated by use of the comet assay and in an azoxymethane (AOM)-induced colon-carcinogenesis study in rats, respectively. We conducted genotoxicity tests ...

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