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Regulation of the Cyclin-dependent Kinase Inhibitor 1A Gene (CDKN1A) by the Repressor BOZF1 through Inhibition of p53 Acetylation and Transcription Factor Sp1 Binding 원문보기

The Journal of biological chemistry, v.288 no.10, 2013년, pp.7053 - 7064  

Kim, Min-Kyeong (From the Department of Biochemistry and Molecular Biology, Brain Korea 21 Project for Medical Science, Severance Biomedical Research Institute, Yonsei University School of Medicine, 134 ShinChon-Dong, SeoDaeMoon-Ku, Seoul 120-752, Korea,) ,  Jeon, Bu-Nam (From the Department of Biochemistry and Molecular Biology, Brain Korea 21 Project for Medical Science, Severance Biomedical Research Institute, Yonsei University School of Medicine, 134 ShinChon-Dong, SeoDaeMoon-Ku, Seoul 120-752, Korea,) ,  Koh, Dong-In (From the Department of Biochemistry and Molecular Biology, Brain Korea 21 Project for Medical Science, Severance Biomedical Research Institute, Yonsei University School of Medicine, 134 ShinChon-Dong, SeoDaeMoon-Ku, Seoul 120-752, Korea,) ,  Kim, Kyung-Sup (From the Department of Biochemistry and Molecular Biology, Brain Korea 21 Project for Medical Science, Severance Biomedical Research Institute, Yonsei University School of Medicine, 134 ShinChon-Dong, SeoDaeMoon-Ku, Seoul 120-752, Korea,) ,  Park, So-Yoon (Department of Pathology, SoonChunHyang U) ,  Yun, Chae-Ok ,  Hur, Man-Wook

Abstract AI-Helper 아이콘AI-Helper

The human POZ domain and Krüppel-like zinc finger (POK) family proteins play important roles in the regulation of apoptosis, cell proliferation, differentiation, development, oncogenesis, and tumor suppression. A novel POK family transcription factor, BTB/POZ and zinc finger domains factor on...

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참고문헌 (46)

  1. Brief. Funct. Genomic. Proteomic. Costoya 6 8 2007 10.1093/bfgp/elm002 Functional analysis of the role of POK transcriptional repressors 

  2. Trends Cell Biol. Kelly 16 578 2006 10.1016/j.tcb.2006.09.003 POZ for effect-POZ-ZF transcription factors in cancer and development 

  3. Science Ye 262 747 1993 10.1126/science.8235596 Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma 

  4. Nat. Genet. Kerckaert 5 66 1993 10.1038/ng0993-66 LAZ3, a novel zinc-finger encoding gene, is disrupted by recurring chromosome 3q27 translocations in human lymphomas 

  5. EMBO J. Chen 12 1161 1993 10.1002/j.1460-2075.1993.tb05757.x Fusion between a novel Kruppel-like zinc finger gene and the retinoic acid receptor-α locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia 

  6. Mol. Cell. Biol. Melnick 20 6550 2000 10.1128/MCB.20.17.6550-6567.2000 In-depth mutational analysis of the promyelocytic leukemia zinc finger BTB/POZ domain reveals motifs and residues required for biological and transcriptional functions 

  7. Mol. Cell. Biol. Pessler 17 3786 1997 10.1128/MCB.17.7.3786 Purification and characterization of FBI-1, a cellular factor that binds to the human immunodeficiency virus type 1 inducer of short transcripts 

  8. J. Biol. Chem. Lee 277 26761 2002 10.1074/jbc.M202078200 POZ domain transcription factor, FBI-1, represses transcription of ADH5/FDH by interacting with the zinc finger and interfering with DNA binding activity of Sp1 

  9. Nature Maeda 433 278 2005 10.1038/nature03203 Role of the proto-oncogene Pokemon in cellular transformation and ARF repression 

  10. Oncogene Fujii 16 2159 1998 10.1038/sj.onc.1201976 Methylation of the HIC-1 candidate tumor suppressor gene in human breast cancer 

  11. Nat. Med. Wales 1 570 1995 10.1038/nm0695-570 p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3 

  12. EMBO J. Peukert 16 5672 1997 10.1093/emboj/16.18.5672 An alternative pathway for gene regulation by Myc 

  13. Curr. Top. Microbiol. Immunol. Schneider 224 137 1997 Association of Myc with the zinc-finger protein Miz-1 defines a novel pathway for gene regulation by Myc 

  14. Nat. Immunol. Phan 6 1054 2005 10.1038/ni1245 BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells 

  15. Oncogene Yeyati 18 925 1999 10.1038/sj.onc.1202375 Leukemia translocation protein PLZF inhibits cell growth and expression of cyclin A 

  16. J. Biol. Chem. Choi 284 12633 2009 10.1074/jbc.M809794200 Proto-oncogene FBI-1 represses transcription of p21CIP1 by inhibition of transcription activation by p53 and Sp1 

  17. EMBO J. Weber 27 1563 2008 10.1038/emboj.2008.85 Zbtb4 represses transcription of P21CIP1 and controls the cellular response to p53 activation 

  18. J. Pathol. Prives 187 112 1999 10.1002/(SICI)1096-9896(199901)187:1<112::AID-PATH250>3.0.CO;2-3 The p53 pathway 

  19. Annu. Rev. Physiol. King 60 601 1998 10.1146/annurev.physiol.60.1.601 Cell cycle regulation and apoptosis 

  20. Nature Lane 358 15 1992 10.1038/358015a0 Cancer. p53, guardian of the genome 

  21. Nature Evan 411 342 2001 10.1038/35077213 Proliferation, cell cycle and apoptosis in cancer 

  22. Nat. Rev. Cancer Bode 4 793 2004 10.1038/nrc1455 Post-translational modification of p53 in tumorigenesis 

  23. Cell Death Differ. Olsson 14 1561 2007 10.1038/sj.cdd.4402196 How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression? 

  24. Cell el-Deiry 75 817 1993 10.1016/0092-8674(93)90500-P WAF1, a potential mediator of p53 tumor suppression 

  25. Clin. Cancer Res. McKenzie 5 4199 1999 Wild-type p53 can induce p21 and apoptosis in neuroblastoma cells but the DNA damage-induced G1 checkpoint function is attenuated 

  26. Science Bunz 282 1497 1998 10.1126/science.282.5393.1497 Requirement for p53 and p21 to sustain G2 arrest after DNA damage 

  27. Cell Harper 75 805 1993 10.1016/0092-8674(93)90499-G The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases 

  28. Science van den Heuvel 262 2050 1993 10.1126/science.8266103 Distinct roles for cyclin-dependent kinases in cell cycle control 

  29. Cancer Res. Waldman 55 5187 1995 p21 is necessary for the p53-mediated G1 arrest in human cancer cells 

  30. Exp. Cell Res. Gartel 246 280 1999 10.1006/excr.1998.4319 Transcriptional regulation of the p21WAF1/CIP1 gene 

  31. Oncogene Gartel 19 5182 2000 10.1038/sj.onc.1203900 Sp1 and Sp3 activate p21WAF1/CIP1 gene transcription in the Caco-2 colon adenocarcinoma cell line 

  32. J. Biol. Chem. Koutsodontis 276 29116 2001 10.1074/jbc.M104130200 Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein 

  33. Science Canman 281 1677 1998 10.1126/science.281.5383.1677 Activation of the ATM kinase by ionizing radiation and phosphorylation of p53 

  34. Genes Dev. Tibbetts 13 152 1999 10.1101/gad.13.2.152 A role for ATR in the DNA damage-induced phosphorylation of p53 

  35. EMBO J. Ito 20 1331 2001 10.1093/emboj/20.6.1331 p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2 

  36. Mol. Cell Tang 24 827 2006 10.1016/j.molcel.2006.11.021 Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis 

  37. Mol. Cell. Biol. Liu 19 1202 1999 10.1128/MCB.19.2.1202 p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage 

  38. Proc. Natl. Acad. Sci. U.S.A. Luo 101 2259 2004 10.1073/pnas.0308762101 Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo 

  39. Mol. Cell. Biol. Zhao 26 2782 2006 10.1128/MCB.26.7.2782-2790.2006 Acetylation of p53 at lysine 373/382 by the histone deacetylase inhibitor depsipeptide induces expression of p21(Waf1/Cip1) 

  40. Mol. Cell. Biol. Chao 26 6859 2006 10.1128/MCB.00062-06 Acetylation of mouse p53 at lysine 317 negatively regulates p53 apoptotic activities after DNA damage 

  41. Cell Luo 107 137 2001 10.1016/S0092-8674(01)00524-4 Negative control of p53 by Sir2α promotes cell survival under stress 

  42. Nature Luo 408 377 2000 10.1038/35042612 Deacetylation of p53 modulates its effect on cell growth and apoptosis 

  43. J. Biol. Chem. Jeon 284 17935 2009 10.1074/jbc.M809559200 ZBTB2, a novel master regulator of the p53 pathway 

  44. Oncogene Lee 31 1442 2012 10.1038/onc.2011.331 The proto-oncoprotein KR-POK represses transcriptional activation of CDKN1A by MIZ-1 through competitive binding 

  45. Cancer Res. Jeon 72 1137 2012 10.1158/0008-5472.CAN-11-2433 KR-POK interacts with p53 and represses its ability to activate transcription of p21WAF1/CDKN1A 

  46. J. Biol. Chem. Koh 284 19856 2009 10.1074/jbc.M109.025817 A novel POK family transcription factor, ZBTB5, represses transcription of p21CIP1 gene 

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