[논문]Joint effects of mitochondrial DNA 5178 C/A polymorphism and coffee consumption or alcohol consumption on clustering of cardiovascular risk factors in middle-aged Japanese men: a cross-sectional study

Ito, Taku; Kokaze, Akatsuki; Ishikawa, Mamoru; Matsunaga, Naomi; Karita, Kanae; Yoshida, Masao; Ohtsu, Tadahiro; Ochiai, Hirotaka; Shirasawa, Takako; Nanri, Hinako; Hoshino, Hiromi; Takashima, Yutaka

doi:10.1186/2251-6581-13-4

Joint effects of mitochondrial DNA 5178 C/A polymorphism and coffee consumption or alcohol consumption on clustering of cardiovascular risk factors in middle-aged Japanese men: a cross-sectional study 원문보기

Journal of diabetes and metabolic disorders, v.13, 2014년, pp.4 - 4

Ito, Taku (Department of Public Health, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan) , Kokaze, Akatsuki (Department of Public Health, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan) , Ishikawa, Mamoru (Department of Public Health, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka-shi, Tokyo 181-8611, Japan) , Matsunaga, Naomi (Department of Public Health, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka-shi, Tokyo 181-8611, Japan) , Karita, Kanae (Department of Public Health, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka-shi, Tokyo 181-8611, Japan) , Yoshida, Masao (Department of Public Health, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka-shi, Tokyo 181-8611, Japan) , Ohtsu, Tadahiro (Department of Public Health, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan) , Ochiai, Hirotaka (Department of Public Health, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan) , Shirasawa, Takako (Department of Public Health, Showa U) , Nanri, Hinako , Hoshino, Hiromi , Takashima, Yutaka

Abstract ▼ AI-Helper

BackgroundLongevity-associated mitochondrial DNA 5178 (Mt5178) C/A reportedly modulates the effects of coffee consumption on the risk of hypertension, dyslipidemia and abnormal glucose tolerance, and those of alcohol consumption on the risk of hypertension, dyslipidemia and hyperuricemia in middle-aged Japanese men. However, there has been no research examining whether Mt5178 C/A polymorphism influences the effects of coffee consumption or alcohol consumption on the clustering of cardiovascular risk factors (CRFs).MethodsA total of 332 male subjects (mean age ± SD, 52.8 ± 7.8 years) were selected from among individuals visiting the hospital for regular medical check-ups. After Mt5178 C/A genotyping, a cross-sectional study assessing the joint effects of Mt5178 C/A polymorphism and coffee consumption or alcohol consumption on the clustering of CRFs, namely hypertension, abnormal glucose tolerance, hyper-low-density lipoprotein cholesterolemia, hypo-high density lipoprotein cholesterolemia, hypertriglyceridemia and hyperuricemia, was then conducted.ResultsAfter adjustment for confounding factors, significant and negative associations were observed between coffee consumption and clustering of ≥2 CRFs in subjects with Mt5178C. The adjusted odds ratio (OR) for the clustering of ≥2 or ≥3 CRFs was significantly lower in subjects who consumed 1–3 cups of coffee per day than in those who consumed <1 cup of coffee per day (OR = 0.496, 95% confidence interval (CI): 0.249–0.989, and OR = 0.369, 95% CI: 0.165–0.826, respectively). On the other hand, after adjustment, positive associations between coffee consumption and clustering of ≥2 CRFs were observed in subjects with Mt5178A. However, these associations did not reach a significant level. For Mt5178C genotypic men, the adjusted OR for the clustering of ≥2 or ≥3 CRFs was significantly higher in daily drinkers than in occasional drinkers (OR = 2.737, 95% CI: 1.361–5.502, and OR = 3.024, 95% CI: 1.269–7.210, respectively). On the other hand, the association between Mt5178A genotype and the clustering of ≥2 or ≥3 CRFs did not appear to depend on alcohol consumption.ConclusionsThe present results suggest that Mt5178 C/A polymorphism modifies the effects of coffee consumption or alcohol consumption on the clustering of CRFs in middle-aged Japanese men.

주제어

참고문헌 (34)

Cannon CP Cardiovascular disease and modifiable cardiometabolic risk factors Clin Cornerstone 2007 8 11 28 10.1016/S1098-3597(07)80025-1 18452839

상세보기
Kim SY Guevara JP Kim KM Choi HK Heitjan DF Albert DA Hyperuricemia and coronary heart disease: a systematic review and meta-analysis Arthritis Care Res (Hoboken) 2010 62 170 180 20191515

상세보기
Puddu P Puddu GM Cravero E De Pascalis S Muscari A The emerging role of cardiovascular risk factor-induced mitochondrial dysfunction in atherogenesis J Biomed Sci 2009 16 112 10.1186/1423-0127-16-112 20003216

상세보기
Yu E Mercer J Bennett M Mitochondria in vascular disease Cardiovasc Res 2012 95 173 182 10.1093/cvr/cvs111 22392270

상세보기
Tanaka M Gong JS Zhang J Yoneda M Yagi K Mitochondrial genotype associated with longevity Lancet 1998 351 185 186 10.1016/S0140-6736(05)78211-8 9449878

상세보기
Alexe G Fuku E Bilal E Ueno H Nishigaki Y Fujita Y Ito M Arai Y Hirose N Bhanot G Tanaka M Enrichment of longevity phenotype in mtDNA haplogroups D4b2b, D4a, and D5 in the Japanese population Hum Genet 2007 121 347 356 10.1007/s00439-007-0330-6 17308896

상세보기
Mukae S Aoki S Itoh S Sato R Nishio K Iwata T Katagiri T Mitochondrial 5178A/C genotype is associated with acute myocardial infarction Circ J 2003 67 16 20 10.1253/circj.67.16 12520145

상세보기
Takagi K Yamada Y Gong JS Sone T Yokota M Tanaka M Association of a 5178C → A (Leu237Met) polymorphism in the mitochondrial DNA with a low prevalence of myocardial infarction in Japanese individuals Atherosclerosis 2004 175 281 286 10.1016/j.atherosclerosis.2004.03.008 15262184

상세보기
Ohkubo R Nakagawa M Ikeda K Kodama T Arimura K Akiba S Saito M Ookatsu Y Atsuchi Y Yamano Y Osame M Cerebrovascular disorders and genetic polymorphisms: mitochondrial DNA5178C is predominant in cerebrovascular disorders J Neurol Sci 2002 198 31 35 10.1016/S0022-510X(02)00055-2 12039661

상세보기
Kokaze A Ishikawa M Matsunaga N Karita K Yoshida M Ohtsu T Shirasawa T Sekii H Ito T Kawamoto T Takashima Y NADH dehydrogenase subunit-2 237 Leu/Met polymorphism modulates the effects of coffee consumption on the risk of hypertension in middle-aged Japanese men J Epidemiol 2009 19 231 236 10.2188/jea.JE20081040 19667492

상세보기
Kokaze A Ishikawa M Matsunaga N Karita K Yoshida M Shimada N Ohtsu T Shirasawa T Ochiai H Kawamoto T Ito T Hoshino H Takashima Y Combined effect of longevity-associated mitochondrial DNA 5178 C/A polymorphism and coffee consumption on the risk of hyper-LDL cholesterolemia in middle-aged Japanese men J Hum Genet 2010 55 577 581 10.1038/jhg.2010.71 20555337

상세보기
Kokaze A Ishikawa M Matsunaga N Karita K Yoshida M Ohtsu T Shirasawa T Haseba Y Satoh M Teruya K Hoshino H Takashima Y Bentely JV, Keller MA Longevity-associated mitochondrial DNA 5178 C/A polymorphism modifies the effect of coffee consumption on glucose tolerance in middle-aged Japanese men Handbook on longevity: genetics, diet and disease 2009 New York: Nova Science Publishers 139 160
Kokaze A Ishikawa M Matsunaga N Yoshida M Satoh M Teruya K Masuda Y Honmyo R Uchida Y Takashima Y NADH dehydrogenase subunit-2 237 Leu/Met polymorphism modifies the effects of alcohol consumption on risk for hypertension in middle-aged Japanese men Hypertens Res 2007 30 213 218 10.1291/hypres.30.213 17510502

상세보기
Kawamoto T Kokaze A Ishikawa M Matsunaga N Karita K Yoshida M Shimada N Ohtsu T Shirasawa T Ochiai H Ito T Hoshino H Takashima Y Joint effect of longevity-associated mitochondrial DNA 5178 C/A polymorphism and alcohol consumption on risk of hyper-LDL cholesterolemia in middle-aged Japanese men Lipids Health Dis 2011 10 105 10.1186/1476-511X-10-105 21702983

상세보기
Kokaze A Ishikawa M Matsunaga N Yoshida M Satoh M Teruya K Honmyo R Yorimitsu M Masuda Y Uchida Y Takashima Y Longevity-associated NADH dehydrogenase subunit-2 237 Leu/Met polymorphism influences the effects of alcohol consumption on serum uric acid levels in nonobese Japanese men J Hum Genet 2006 51 765 771 10.1007/s10038-006-0018-0 16897192

상세보기
Kokaze A Ishikawa M Matsunaga N Yoshida M Sekine Y Teruya K Takeda N Sumiya Y Uchida Y Takashima Y Association of the mitochondrial DNA 5178 A/C polymorphism with serum lipid levels in the Japanese population Hum Genet 2001 109 521 525 10.1007/s004390100602 11735027

상세보기
Friedewald WT Levy RI Fredrickson DS Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge Clin Chem 1972 18 499 502 4337382

상세보기
Teramoto T Sasaki J Ueshima H Egusa G Kinoshita M Shimamoto K Daida H Biro S Hirobe K Funahashi T Yokote K Yokode M Japan Atherosclerosis Society (JAS) Committee for Epidemiology and Clinical Management of Atherosclerosis Diagnosis criteria for dyslipidemia. Executive summary of Japan Atherosclerotic Society (JAS) guideline for diagnosis and prevention of atherosclerotic cardiovascular diseases for Japanese J Atheroscler Thromb 2007 14 155 158 10.5551/jat.E537 17827859

상세보기
Ohta Y Tsuchihashi T Onaka U Hasegawa E Clustering of cardiovascular risk factors and blood pressure control status in hypertensive patients Intern Med 2010 49 1483 1487 10.2169/internalmedicine.49.3406 20686278

상세보기
Ashizawa K Imaizumi M Usa T Tominaga T Sera N Hida A Ejima E Neriishi E Soda M Ichimaru S Nakashima E Fujiwara S Maeda R Nagataki S Eguchi K Akahoshi M Metabolic cardiovascular disease risk factors and their clustering in subclinical hypothyroidism Clin Endocrinol (Oxf) 2010 72 689 695 10.1111/j.1365-2265.2009.03697.x 20447067

상세보기
Joseph PG Pare G Anand SS Exploring gene-environment relationship in cardiovascular disease Can J Cardiol 2013 29 37 45 10.1016/j.cjca.2012.10.009 23261319

상세보기
Corrao G Rubbiati L Bagnardi V Zambon A Poikolainen K Alcohol and coronary heart disease: a meta-analysis Addiction 2000 95 1505 1523 10.1046/j.1360-0443.2000.951015056.x 11070527

상세보기
Balk L Hoekstra T Twisk J Relationship between long-term coffee consumption and components of the metabolic syndrome: the Amsterdam Growth and Health Longitudinal Study Eur J Epidemiol 2009 24 203 209 10.1007/s10654-009-9323-1 19274481

상세보기
Hino A Adachi H Enomoto M Furuki K Shigetoh Y Ohtsuka M Kumagae S Hirai Y Jalaldin A Satoh A Imaizumi T Habitual coffee but not green tea consumption is inversely associated with metabolic syndrome: an epidemiological study in a general Japanese population Diabetes Res Clin Pract 2007 76 383 389 10.1016/j.diabres.2006.09.033 17070955

상세보기
Matsuura H Mure K Nishio N Kitano N Nagai N Takeshita T Relationship between coffee consumption and prevalence of metabolic syndrome among Japanese civil servants J Epidemiol 2012 22 160 166 10.2188/jea.JE20110068 22343325

상세보기
Takami H Nakamoto M Uemura H Katsuura S Yamaguchi M Hiyoshi M Sawachika F Juta T Arisawa K Inverse correlation between coffee consumption and prevalence of metabolic syndrome: baseline survey of the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study in Tokushima, Japan J Epidemiol 2013 23 12 20 10.2188/jea.JE20120053 23047663

상세보기
Alkerwi A Boutsen M Vaillant M Barre J Lair ML Albert A Guillaume M Dramaix M Alcohol consumption and the prevalence of metabolic syndrome: a meta-analysis of observational studies Atherosclerosis 2009 204 624 635 10.1016/j.atherosclerosis.2008.10.036 19084839

상세보기
Baik I Shin C Prospective study of alcohol consumption and metabolic syndrome Am J Clin Nutr 2008 87 1455 1463 18469271

상세보기
Lenaz G Bovina C D’Aurelio M Fato R Formiggini G Genova ML Giuliano G Merlo Pich M Paolucci U Parenti Castelli G Ventura B Role of mitochondria in oxidative stress and aging Ann N Y Acad Sci 2002 959 199 213 11976197

상세보기
Ishizaka Y Yamamoto M Toda A Tani M Ishizaka N Relationship between coffee consumption, oxidant status, and antioxidant potential in the Japanese general population Clin Chem Lab Med 2013 51 1951 1959 23612669
Mišík M Hoelzl C Wagner KH Cavin C Moser B Kundi M Simic T Elbling L Kager N Ferk F Ehrlich V Nersesyan A Dušinská M Schilter B Knasmüller S Impact of paper filtered coffee on oxidative DNA-damage: results of a clinical trial Mutat Res 2010 692 42 48 10.1016/j.mrfmmm.2010.08.003 20709087

상세보기
Das SK Vasudevan DM Alcohol-induced oxidative stress Life Sci 2007 81 177 187 10.1016/j.lfs.2007.05.005 17570440

상세보기
Examination Committee of Criteria for ’Obesity Disease’ in Japan, Japan Society for the Study of Obesity New criteria for ’obesity disease’ in Japan Circ J 2002 66 987 992 10.1253/circj.66.987 12419927

상세보기
Otsuka R Imai T Kato Y Ando F Shimokata H Relationship between number of metabolic syndrome components and dietary factors in middle-aged and elderly Japanese subjects Hypertens Res 2010 33 548 554 10.1038/hr.2010.29 20224573

상세보기

표제어: PCR

동의어: Packet Collision Rate

용어 설명 출처 목록 (6)

용어 설명: PCR은 세균 특이성이 있는 primer를 이용하여 적은 수의 세균이 있을지라도 쉽게 검출할 수 있는 유용한 방법이며, 이를 이용하여 구강 내 치면세균막이나 타액에서 직접 세균을 검출할 수 있게 되었다[8].

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관 관리번호, 논문명, 대등논문명, 저자 , 저널/프로시딩명, 발행기관, 발행년, 발행언어, 권, 호, 시작페이지, 끝페이지, ISBN, ISSN, 주제분야, 키워드, 초록(한글), 초록(영문), 저자(소속기관)
저장형식	Text(ASCII format) Excel format RefWorks Direct Export RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증

Joint effects of mitochondrial DNA 5178 C/A polymorphism and coffee consumption or alcohol consumption on clustering of cardiovascular risk factors in middle-aged Japanese men: a cross-sectional study 원문보기

Abstract ▼ AI-Helper

주제어

참고문헌 (34)

이 논문을 인용한 문헌

관련 콘텐츠

원문 보기

원문 URL 링크

오픈액세스(OA) 유형

이 논문과 함께 이용한 콘텐츠

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트