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NTIS 바로가기International journal of oncology, v.46 no.2, 2015년, pp.578 - 586
LI, YONG-CHUN (Department of Oriental Medicine Materials, Dongshin University, Naju, Jeonnam 520-714, Republic of Korea) , KIM, BONG-HEE (Chungnam National University, Yuseong, Daejeon 305-764, Republic of Korea) , CHO, SOON-CHANG (Research Institute, NaturePureKorea Inc., Damyang 517-803, Republic of Korea) , BANG, MI-AE (Food Industry Development Team, Jeonnam Biofood Technology Center, Naju, Republic of Korea) , KIM, SUNMIN (Department of Oriental Medicine Materials, Dongshin University, Naju, Jeonnam 520-714, Republic of Korea) , PARK, DAE-HUN (Department of Oriental Medicine Materials, Dongshin University, Naju, Jeonnam 520-714, Republic of Korea)
We evaluated the cytostatic effect of 6,7-di-O-acetylsinococuline (FK-3000) isolated from Stephania delavayi Diels. against breast carcinoma cell lines MDA-MB-231 and MCF-7. FK-3000 suppressed CDC25B phosphorylation directly and indirectly via p38 MAPK phosphorylation. CDC25B dephosphorylation decre...
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