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Albumin and its application in drug delivery

Expert opinion on drug delivery, v.12 no.5, 2015년, pp.793 - 812  

Sleep, Darrell (Biopharma R&D, Novozymes Biopharma UK Ltd., Castle Court, 59 Castle Boulevard, Nottingham, NG7 1FD, UK)

Abstract AI-Helper 아이콘AI-Helper

Introduction: Rapid clearance of drugs from the body results in short therapeutic half-life and is an integral property of many protein and peptide-based drugs. To maintain the desired therapeutic effect patients are required to administer higher doses more frequently, which is inconvenient and risk...

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참고문헌 (150)

  1. All about albumin: biochemistry, genetics, and medical applications Peters T 1996 

  2. Comp Cont Educ Pract Vet Throop JL 931 26 12 2004 

  3. Anderson, Clark L., Chaudhury, Chaity, Kim, Jonghan, Bronson, C.L., Wani, Manzoor A., Mohanty, Sudhasri. Perspective – FcRn transports albumin: relevance to immunology and medicine. Trends in immunology, vol.27, no.7, 343-348.

  4. Kim, Jonghan, Hayton, William L., Robinson, John M., Anderson, Clark L.. Kinetics of FcRn-mediated recycling of IgG and albumin in human: Pathophysiology and therapeutic implications using a simplified mechanism-based model. Clinical immunology : the official journal of the Clinical Immunology Society, vol.122, no.2, 146-155.

  5. Sleep, D., Cameron, J., Evans, L.R.. Albumin as a versatile platform for drug half-life extension. Biochimica et biophysica acta, General subjects, vol.1830, no.12, 5526-5534.

  6. Dockal, Michael, Carter, Daniel C., Rüker, Florian. The Three Recombinant Domains of Human Serum Albumin. The Journal of biological chemistry, vol.274, no.41, 29303-29310.

  7. Fanali, G., di Masi, A., Trezza, V., Marino, M., Fasano, M., Ascenzi, P.. Human serum albumin: From bench to bedside. Molecular aspects of medicine, vol.33, no.3, 209-290.

  8. Dockal, Michael, Carter, Daniel C., Rüker, Florian. Conformational Transitions of the Three Recombinant Domains of Human Serum Albumin Depending on pH. The Journal of biological chemistry, vol.275, no.5, 3042-3050.

  9. Ghuman, Jamie, Zunszain, Patricia A., Petitpas, Isabelle, Bhattacharya, Ananyo A., Otagiri, Masaki, Curry, Stephen. Structural Basis of the Drug-binding Specificity of Human Serum Albumin. Journal of molecular biology, vol.353, no.1, 38-52.

  10. Gundry, Rebekah L., Fu, Qin, Jelinek, Christine A., Van Eyk, Jennifer E., Cotter, Robert J.. Investigation of an albumin-enriched fraction of human serum and its albuminome. Proteomics. Clinical applications, vol.1, no.1, 73-88.

  11. Fasano, Mauro, Curry, Stephen, Terreno, Enzo, Galliano, Monica, Fanali, Gabriella, Narciso, Pasquale, Notari, Stefania, Ascenzi, Paolo. The extraordinary ligand binding properties of human serum albumin. IUBMB life, vol.57, no.12, 787-796.

  12. Yamasaki, K., Chuang, V.T.G., Maruyama, T., Otagiri, M.. Albumin-drug interaction and its clinical implication. Biochimica et biophysica acta, General subjects, vol.1830, no.12, 5435-5443.

  13. Ha, C.E., Bhagavan, N.V.. Novel insights into the pleiotropic effects of human serum albumin in health and disease. Biochimica et biophysica acta, General subjects, vol.1830, no.12, 5486-5493.

  14. Varshney, Ankita, Sen, Priyankar, Ahmad, Ejaz, Rehan, Mohd., Subbarao, Naidu, Khan, Rizwan Hasan. Ligand binding strategies of human serum albumin: How can the cargo be utilized?. Chirality : the pharmacological, biological, and chemical consequences of molecular asymmetry, vol.22, no.1, 77-87.

  15. Bal, W., Sokolowska, M., Kurowska, E., Faller, P.. Binding of transition metal ions to albumin: Sites, affinities and rates. Biochimica et biophysica acta, General subjects, vol.1830, no.12, 5444-5455.

  16. Stewart, Alan J., Blindauer, Claudia A., Berezenko, Stephen, Sleep, Darrell, Tooth, David, Sadler, Peter J.. Role of Tyr84 in controlling the reactivity of Cys34 of human albumin. The FEBS journal, vol.272, no.2, 353-362.

  17. Ishima, Y., Kragh-Hansen, U., Maruyama, T., Otagiri, M.. Albumin as a Nitric Oxide-Traffic Protein: Characterization, Biochemistry and Possible Future Therapeutic Applications. Drug metabolism and pharmacokinetics, vol.24, no.4, 308-317.

  18. Hamilton, J.A.. NMR reveals molecular interactions and dynamics of fatty acid binding to albumin. Biochimica et biophysica acta, General subjects, vol.1830, no.12, 5418-5426.

  19. Curry, Stephen, Mandelkow, Hendrik, Brick, Peter, Franks, Nick. Crystal structure of human serum albumin complexed with fatty acid reveals an asymmetric distribution of binding sites. Nature structural biology, vol.5, no.9, 827-835.

  20. Bhattacharya, A.A., Grune, T., Curry, S.. Crystallographic analysis reveals common modes of binding of medium and long-chain fatty acids to human serum albumin. Journal of molecular biology, vol.303, no.5, 721-732.

  21. Fujiwara, S.i., Amisaki, T.. Fatty acid binding to serum albumin: Molecular simulation approaches. Biochimica et biophysica acta, General subjects, vol.1830, no.12, 5427-5434.

  22. J Lipid Res Saifer A 268 2 3 1961 10.1016/S0022-2275(20)39014-3 

  23. Merlot, Angelica M., Kalinowski, Danuta S., Richardson, Des R.. Unraveling the mysteries of serum albumin—more than just a serum protein. Frontiers in physiology, vol.5, 299-.

  24. Gradishar, William J. Albumin-bound paclitaxel: a next-generation taxane. Expert opinion on pharmacotherapy, vol.7, no.8, 1041-1053.

  25. J Med Sci Malik AB 13 2 1 2009 

  26. Amsellem, Sabine, Gburek, Jakub, Hamard, Ghislaine, Nielsen, Rikke, Willnow, Thomas E., Devuyst, Olivier, Nexo, Ebba, Verroust, Pierre J., Christensen, Erik I., Kozyraki, Renata. Cubilin Is Essential for Albumin Reabsorption in the Renal Proximal Tubule. Journal of the American Society of Nephrology : JASN, vol.21, no.11, 1859-1867.

  27. Saito, Akihiko, Sato, Hiroyoshi, Iino, Noriaki, Takeda, Tetsuro. Molecular Mechanisms of Receptor-Mediated Endocytosis in the Renal Proximal Tubular Epithelium. Journal of biomedicine & biotechnology, vol.2010, 403272-.

  28. Chaudhury, Chaity, Mehnaz, Samina, Robinson, John M., Hayton, William L., Pearl, Dennis K., Roopenian, Derry C., Anderson, Clark L.. The Major Histocompatibility Complex–related Fc Receptor for IgG (FcRn) Binds Albumin and Prolongs Its Lifespan. The Journal of experimental medicine, vol.197, no.3, 315-322.

  29. Roopenian, Derry C., Akilesh, Shreeram. FcRn: the neonatal Fc receptor comes of age. Nature reviews. Immunology, vol.7, no.9, 715-725.

  30. Andersen, J.T., Sandlie, I.. The Versatile MHC Class I-related FcRn Protects IgG and Albumin from Degradation: Implications for Development of New Diagnostics and Therapeutics. Drug metabolism and pharmacokinetics, vol.24, no.4, 318-332.

  31. Baker, Kristi, Qiao, Shuo-Wang, Kuo, Timothy, Kobayashi, Kanna, Yoshida, Masaru, Lencer, Wayne I., Blumberg, Richard S.. Immune and non-immune functions of the (not so) neonatal Fc receptor, FcRn. Seminars in Immunopathology, vol.31, no.2, 223-236.

  32. Kuo, Timothy T., Baker, Kristi, Yoshida, Masaru, Qiao, Shuo-Wang, Aveson, Victoria G., Lencer, Wayne I., Blumberg, Richard S.. Neonatal Fc Receptor: From Immunity to Therapeutics. Journal of clinical immunology, vol.30, no.6, 777-789.

  33. Roopenian, Derry C., Sun, Victor Z.. Clinical Ramifications of the MHC Family Fc Receptor FcRn. Journal of clinical immunology, vol.30, no.6, 790-797.

  34. Chaudhury, C., Brooks, C. L., Carter, D. C., Robinson, J. M., Anderson, C. L.. Albumin Binding to FcRn: Distinct from the FcRn−IgG Interaction. Biochemistry, vol.45, no.15, 4983-4990.

  35. Rath, Timo, Kuo, Timothy T., Baker, Kristi, Qiao, Shuo-Wang, Kobayashi, Kanna, Yoshida, Masaru, Roopenian, Derry, Fiebiger, Edda, Lencer, Wayne I., Blumberg, Richard S.. The Immunologic Functions of the Neonatal Fc Receptor for IgG. Journal of clinical immunology, vol.33, no.suppl1, 9-17.

  36. Simister, Neil E., Mostov, Keith E.. An Fc receptor structurally related to MHC class I antigens. Nature, vol.337, no.6203, 184-187.

  37. Burmeister, Wilhelm P., Gastinel, Louis N., Simister, Neil E., Blum, Michael L., Bjorkman, Pamela J.. Crystal structure at 2.2 Å resolution of the MHC-related neonatal Fc receptor. Nature, vol.372, no.6504, 336-343.

  38. West Jr., A. P., Bjorkman, P. J.. Crystal Structure and Immunoglobulin G Binding Properties of the Human Major Histocompatibility Complex-Related Fc Receptor,. Biochemistry, vol.39, no.32, 9698-9708.

  39. Gastinel, L N, Simister, N E, Bjorkman, P J. Expression and crystallization of a soluble and functional form of an Fc receptor related to class I histocompatibility molecules.. Proceedings of the National Academy of Sciences of the United States of America, vol.89, no.2, 638-642.

  40. Wani, Manzoor A., Haynes, Lynn D., Kim, Jonghan, Bronson, C. L., Chaudhury, Chaity, Mohanty, Sudhasri, Waldmann, Thomas A., Robinson, John M., Anderson, Clark L.. Familial hypercatabolic hypoproteinemia caused by deficiency of the neonatal Fc receptor, FcRn, due to a mutant β2-microglobulin gene. Proceedings of the National Academy of Sciences of the United States of America, vol.103, no.13, 5084-5089.

  41. Waldmann, T A, Terry, W D. Familial hypercatabolic hypoproteinemia. A disorder of endogenous catabolism of albumin and immunoglobulin.. The Journal of clinical investigation, vol.86, no.6, 2093-2098.

  42. Terje Andersen, Jan, Bekele Daba, Muluneh, Berntzen, Gøril, Michaelsen, Terje E., Sandlie, Inger. Cross-species Binding Analyses of Mouse and Human Neonatal Fc Receptor Show Dramatic Differences in Immunoglobulin G and Albumin Binding. The Journal of biological chemistry, vol.285, no.7, 4826-4836.

  43. Andersen, Jan Terje, Dalhus, Bjørn, Cameron, Jason, Daba, Muluneh Bekele, Plumridge, Andrew, Evans, Leslie, Brennan, Stephan O., Gunnarsen, Kristin Støen, Bjørås, Magnar, Sleep, Darrell, Sandlie, Inger. Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor. Nature communications, vol.3, 610-.

  44. Schmidt, Michael M., Townson, Sharon A., Andreucci, Amy J., King, Bracken M., Schirmer, Emily B., Murillo, Alec J., Dombrowski, C., Tisdale, Alison W., Lowden, Patricia A., Masci, Allyson L., Kovalchin, Joseph T., Erbe, David V., Wittrup, K., Furfine, Eric S., Barnes, Thomas M.. Crystal Structure of an HSA/FcRn Complex Reveals Recycling by Competitive Mimicry of HSA Ligands at a pH-Dependent Hydrophobic Interface. Structure, vol.21, no.11, 1966-1978.

  45. Sand, Kine Marita Knudsen, Dalhus, Bjørn, Christianson, Gregory J., Bern, Malin, Foss, Stian, Cameron, Jason, Sleep, Darrell, Bjørås, Magnar, Roopenian, Derry C., Sandlie, Inger, Andersen, Jan Terje. Dissection of the Neonatal Fc Receptor (FcRn)-Albumin Interface Using Mutagenesis and Anti-FcRn Albumin-blocking Antibodies. The Journal of biological chemistry, vol.289, no.24, 17228-17239.

  46. Oganesyan, Vaheh, Damschroder, Melissa M., Cook, Kimberly E., Li, Qing, Gao, Changshou, Wu, Herren, Dall'Acqua, William F.. Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms. The Journal of biological chemistry, vol.289, no.11, 7812-7824.

  47. Andersen, Jan Terje, Dalhus, Bjørn, Viuff, Dorthe, Ravn, Birgitte Thue, Gunnarsen, Kristin Støen, Plumridge, Andrew, Bunting, Karen, Antunes, Filipa, Williamson, Rebecca, Athwal, Steven, Allan, Elizabeth, Evans, Leslie, Bjørås, Magnar, Kjærulff, Søren, Sleep, Darrell, Sandlie, Inger, Cameron, Jason. Extending Serum Half-life of Albumin by Engineering Neonatal Fc Receptor (FcRn) Binding. The Journal of biological chemistry, vol.289, no.19, 13492-13502.

  48. Kragh-Hansen, U., Minchiotti, L., Galliano, M., Peters, T.. Human serum albumin isoforms: Genetic and molecular aspects and functional consequences. Biochimica et biophysica acta, General subjects, vol.1830, no.12, 5405-5417.

  49. Minchiotti, Lorenzo, Galliano, Monica, Kragh-Hansen, Ulrich, Peters Jr., Theodore. Mutations and polymorphisms of the gene of the major human blood protein, serum albumin. Human mutation, vol.29, no.8, 1007-1016.

  50. Bosse, Dietrich, Praus, Michaela, Kiessling, Peter, Nyman, Lars, Andresen, Corina, Waters, Joanne, Schindel, Fritz. Phase I Comparability of Recombinant Human Albumin and Human Serum Albumin. The Journal of clinical pharmacology, vol.45, no.1, 57-67.

  51. Sansonno, D.E., DeTomaso, P., Papanice, M.A., Manghisi, O.G.. An enzyme-linked immunosorbent assay for the detection of autoantibodies to albumin. Journal of immunological methods, vol.90, no.1, 131-136.

  52. Gregor, I., Iberg, N., Berger, W., Fl�ckiger, R.. Albumin-directed antibodies in diabetes: demonstration of human serum albumin-directed IgM autoantibodies. Diabetologia, vol.29, no.8, 481-484.

  53. Baraldini, Mario, Miglio, Federico, Cursaro, Carmela, Stefanini, Giuseppe Francesco, Andreone, Pietro, Micaletti, Enzo, Gasbarrini, Giovanni. Clinical significance of antibodies to polymerized human albumin detected by enzyme-linked immunosorbent assay. La Ricerca in clinica e in laboratorio, vol.18, no.4, 291-300.

  54. Chapman, Joab, Maayan, Channa, Michaelson, Daniel M.. Antibodies to Human Serum Albumin in Familial Dysautonomia. International archives of allergy and immunology, vol.100, no.1, 42-46.

  55. Pires, Eusebio S., Parte, Priyanka P., Meherji, Perveen K., Khan, Shagufta A., Khole, Vrinda V.. Naturally Occurring Anti-albumin Antibodies Are Responsible for False Positivity in Diagnosis of Autoimmune Premature Ovarian Failure. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, vol.54, no.4, 397-405.

  56. Khan, Mohd. Wajid Ali, Qadrie, Zulfkar Latief, Khan, Wahid Ali. Antibodies against Gluco-Oxidatively Modified Human Serum Albumin Detected in Diabetes-Associated Complications. International archives of allergy and immunology, vol.153, no.2, 207-214.

  57. SJÖWALL, CHRISTOPHER, KASTBOM, ALF, ALMROTH, GUNNEL, WETTERÖ, JONAS, SKOGH, THOMAS. Beware of Antibodies to Dietary Proteins in “Antigen-specific” Immunoassays! Falsely Positive Anticytokine Antibody Tests Due to Reactivity with Bovine Serum Albumin in Rheumatoid Arthritis (The Swedish TIRA Project). The Journal of rheumatology, vol.38, no.2, 215-220.

  58. Chen, Z., He, Y., Shi, B., Yang, D.. Human serum albumin from recombinant DNA technology: Challenges and strategies. Biochimica et biophysica acta, General subjects, vol.1830, no.12, 5515-5525.

  59. Biotechnol Appl Biochem Dodsworth N 171 24 2 1996 10.1111/j.1470-8744.1996.tb00397.x 

  60. Kobayashi, Kaoru. Summary of recombinant human serum albumin development. Biologicals : journal of the International Association of Biological Standardization, vol.34, no.1, 55-59.

  61. Blindauer, Claudia A., Harvey, Ian, Bunyan, Kerry E., Stewart, Alan J., Sleep, Darrell, Harrison, David J., Berezenko, Stephen, Sadler, Peter J.. Structure, Properties, and Engineering of the Major Zinc Binding Site on Human Albumin. The Journal of biological chemistry, vol.284, no.34, 23116-23124.

  62. Komatsu, T., Ohmichi, N., Nakagawa, A., Zunszain, P. A., Curry, S., Tsuchida, E.. O2 and CO Binding Properties of Artificial Hemoproteins Formed by Complexing Iron Protoporphyrin IX with Human Serum Albumin Mutants. Journal of the American Chemical Society, vol.127, no.45, 15933-15942.

  63. Iwao, Yasunori, Hiraike, Mikako, Kragh-Hansen, Ulrich, Kawai, Keiichi, Suenaga, Ayaka, Maruyama, Toru, Otagiri, Masaki. Altered chain-length and glycosylation modify the pharmacokinetics of human serum albumin. Biochimica et biophysica acta. Proteins and proteomics, vol.1794, no.4, 634-641.

  64. Sheffield, William P, Marques, Janey A, Bhakta, Varsha, Smith, Ian J. Modulation of Clearance of Recombinant Serum Albumin by Either Glycosylation or Truncation. Thrombosis research, vol.99, no.6, 613-621.

  65. Nakajou, Keisuke, Watanabe, Hiroshi, Kragh-Hansen, Ulrich, Maruyama, Toru, Otagiri, Masaki. The effect of glycation on the structure, function and biological fate of human serum albumin as revealed by recombinant mutants. Biochimica et biophysica acta, General subjects, vol.1623, no.2, 88-97.

  66. Iwao, Yasunori, Anraku, Makoto, Yamasaki, Keishi, Kragh-Hansen, Ulrich, Kawai, Keiichi, Maruyama, Toru, Otagiri, Masaki. Oxidation of Arg-410 promotes the elimination of human serum albumin. Biochimica et biophysica acta. Proteins and proteomics, vol.1764, no.4, 743-749.

  67. Iwao, Yasunori, Hiraike, Mikako, Kragh-Hansen, Ulrich, Mera, Katsumi, Noguchi, Taishi, Anraku, Makoto, Kawai, Keiichi, Maruyama, Toru, Otagiri, Masaki. Changes of net charge and α-helical content affect the pharmacokinetic properties of human serum albumin. Biochimica et biophysica acta. Proteins and proteomics, vol.1774, no.12, 1582-1590.

  68. J Biol Chem Schnitzer JE 24544 267 34 1992 10.1016/S0021-9258(18)35799-5 

  69. J Biol Chem Schnitzer JE 7562 268 10 1993 10.1016/S0021-9258(18)53212-9 

  70. Elsadek, Bakheet, Kratz, Felix. Impact of albumin on drug delivery — New applications on the horizon. Journal of controlled release : official journal of the Controlled Release Society, vol.157, no.1, 4-28.

  71. Kratz, F., Elsadek, B.. Clinical impact of serum proteins on drug delivery. Journal of controlled release : official journal of the Controlled Release Society, vol.161, no.2, 429-445.

  72. Trüssel, Sabrina, Dumelin, Christoph, Frey, Katharina, Villa, Alessandra, Buller, Fabian, Neri, Dario. New Strategy for the Extension of the Serum Half-Life of Antibody Fragments. Bioconjugate chemistry, vol.20, no.12, 2286-2292.

  73. Zobel, Kerry, Koehler, Michael F.T., Beresini, Maureen H., Caris, Lisa D., Combs, Daniel. Phosphate ester serum albumin affinity tags greatly improve peptide half-life in vivo. Bioorganic & medicinal chemistry letters, vol.13, no.9, 1513-1515.

  74. Home, Philip, Kurtzhals, Peter. Insulin detemir: from concept to clinical experience. Expert opinion on pharmacotherapy, vol.7, no.3, 325-343.

  75. Kurtzhals, P, Havelund, S, Jonassen, I, Kiehr, B, Larsen, U D, Ribel, U, Markussen, J. Albumin binding of insulins acylated with fatty acids: characterization of the ligand-protein interaction and correlation between binding affinity and timing of the insulin effect in vivo. The Biochemical journal, vol.312, no.3, 725-731.

  76. Gough, S. C. L., Harris, S., Woo, V., Davies, M.. Insulin degludec: overview of a novel ultra long‐acting basal insulin. Diabetes, obesity & metabolism, vol.15, no.4, 301-309.

  77. Bode, B.. An overview of the pharmacokinetics, efficacy and safety of liraglutide. Diabetes research and clinical practice, vol.97, no.1, 27-42.

  78. Diabetes Metab Syndr Obes Rigato M 107 7 2014 

  79. Ryan, G.J., Foster, K.T., Jobe, L.J.. Review of the Therapeutic Uses of Liraglutide. Clinical therapeutics, vol.33, no.7, 793-811.

  80. Gotfredsen, Carsten F., Mølck, Anne-Marie, Thorup, Inger, Nyborg, Niels C. Berg, Salanti, Zaki, Knudsen, Lotte Bjerre, Larsen, Marianne O.. The Human GLP-1 Analogs Liraglutide and Semaglutide: Absence of Histopathological Effects on the Pancreas in Nonhuman Primates. Diabetes, vol.63, no.7, 2486-2497.

  81. Zheng, Yao-Rong, Suntharalingam, Kogularamanan, Johnstone, Timothy C., Yoo, Hyunsuk, Lin, Wei, Brooks, Jamar G., Lippard, Stephen J.. Pt(IV) Prodrugs Designed to Bind Non-Covalently to Human Serum Albumin for Drug Delivery. Journal of the American Chemical Society, vol.136, no.24, 8790-8798.

  82. 10.1002/9781118354599.ch11 

  83. Jonsson, A., Dogan, J., Herne, N., Abrahmsen, L., Nygren, P.-A.. Engineering of a femtomolar affinity binding protein to human serum albumin. Protein engineering, design & selection : PEDS, vol.21, no.8, 515-527.

  84. Nilvebrant, Johan, Hober, Sophia. The albumin-binding domain as a scaffold for protein engineering. Computational and structural biotechnology journal, vol.6, no.7, e201303009-.

  85. Angelini, Alessandro, Morales-Sanfrutos, Julia, Diderich, Philippe, Chen, Shiyu, Heinis, Christian. Bicyclization and Tethering to Albumin Yields Long-Acting Peptide Antagonists. Journal of medicinal chemistry, vol.55, no.22, 10187-10197.

  86. Dennis, Mark S., Zhang, Min, Meng, Y. Gloria, Kadkhodayan, Miryam, Kirchhofer, Daniel, Combs, Dan, Damico, Lisa A.. Albumin Binding as a General Strategy for Improving the Pharmacokinetics of Proteins. The Journal of biological chemistry, vol.277, no.38, 35035-35043.

  87. Nguyen, Allen, Reyes II, Arthur E., Zhang, Min, McDonald, Paul, Wong, Wai Lee T., Damico, Lisa A., Dennis, Mark S.. The pharmacokinetics of an albumin-binding Fab (AB.Fab) can be modulated as a function of affinity for albumin. Protein engineering, design & selection : PEDS, vol.19, no.7, 291-297.

  88. Holt, Lucy J, Basran, Amrik, Jones, Kate, Chorlton, Jennifer, Jespers, Laurent S, Brewis, Neil D, Tomlinson, Ian M. Anti-serum albumin domain antibodies for extending the half-lives of short lived drugs.. Protein engineering, design & selection : PEDS, vol.21, no.5, 283-288.

  89. Tijink, Bernard M., Laeremans, Toon, Budde, Marianne, Walsum, Marijke Stigter-van, Dreier, Torsten, de Haard, Hans J., Leemans, C. René, van Dongen, Guus A.M.S.. Improved tumor targeting of anti-epidermal growth factor receptor Nanobodies through albumin binding: taking advantage of modular Nanobody technology. Molecular cancer therapeutics, vol.7, no.8, 2288-2297.

  90. Roovers, Rob C., Laeremans, Toon, Huang, Lieven, De Taeye, Severine, Verkleij, Arie J., Revets, Hilde, de Haard, Hans J., van Bergen en Henegouwen, Paul M. P.. Efficient inhibition of EGFR signalling and of tumour growth by antagonistic anti-EGFR Nanobodies. Cancer immunology, immunotherapy : CII, vol.56, no.3, 303-317.

  91. Lipovšek, D.. Adnectins: engineered target-binding protein therapeutics. Protein engineering, design & selection : PEDS, vol.24, no.1, 3-9.

  92. Levy, Odile E., Jodka, Carolyn M., Ren, Shijun Steven, Mamedova, Lala, Sharma, Abhinandini, Samant, Manoj, D’Souza, Lawrence J., Soares, Christopher J., Yuskin, Diane R., Jin, Li Jenny, Parkes, David G., Tatarkiewicz, Krystyna, Ghosh, Soumitra S.. Novel Exenatide Analogs with Peptidic Albumin Binding Domains: Potent Anti-Diabetic Agents with Extended Duration of Action. PloS one, vol.9, no.2, e87704-.

  93. Paige, Aimee Guider, Whitcomb, K. Lane, Liu, Jennifer, Kinstler, Olaf. Prolonged Circulation of Recombinant Human Granulocyte–Colony Stimulating Factor by Covalent Linkage to Albumin Through a Heterobifunctional Polyethylene Glycol. Pharmaceutical research, vol.12, no.12, 1883-1888.

  94. Leger, R., Benquet, C., Huang, X., Quraishi, O., van Wyk, P., Bridon, D.. Kringle 5 peptide-albumin conjugates with anti-migratory activity. Bioorganic & medicinal chemistry letters, vol.14, no.4, 841-845.

  95. Simon, Manuel, Frey, Raphael, Zangemeister-Wittke, Uwe, Plückthun, Andreas. Orthogonal Assembly of a Designed Ankyrin Repeat Protein–Cytotoxin Conjugate with a Clickable Serum Albumin Module for Half-Life Extension. Bioconjugate chemistry, vol.24, no.11, 1955-1966.

  96. Stoddart, Cheryl A., Nault, Geneviève, Galkina, Sofiya A., Thibaudeau, Karen, Bakis, Peter, Bousquet-Gagnon, Nathalie, Robitaille, Martin, Bellomo, Maryanne, Paradis, Véronique, Liscourt, Patricia, Lobach, Alexandra, Rivard, Marie-Ève, Ptak, Roger G., Mankowski, Marie K., Bridon, Dominique, Quraishi, Omar. Albumin-conjugated C34 Peptide HIV-1 Fusion Inhibitor : EQUIPOTENT TO C34 AND T-20 IN VITRO WITH SUSTAINED ACTIVITY IN SCID-HU THY/LIV MICE. The Journal of biological chemistry, vol.283, no.49, 34045-34052.

  97. Thibaudeau, K., Leger, R., Huang, X., Robitaille, M., Quraishi, O., Soucy, C., Bousquet-Gagnon, N., van Wyk, P., Paradis, V., Castaigne, J.-P., Bridon, D.. Synthesis and Evaluation of Insulin−Human Serum Albumin Conjugates. Bioconjugate chemistry, vol.16, no.4, 1000-1008.

  98. Holmes, D. L., Thibaudeau, K., L'Archeveque, B., Milner, P. G., Ezrin, A. M., Bridon, D. P.. Site Specific 1:1 Opioid:Albumin Conjugate with in Vitro Activity and Long in Vivo Duration. Bioconjugate chemistry, vol.11, no.4, 439-444.

  99. Ehrlich, George K., Michel, Hanspeter, Truitt, Theresa, Riboulet, William, Pop-Damkov, Petar, Goelzer, Petra, Hainzl, Dominik, Qureshi, Farooq, Lueckel, Barbara, Danho, Waleed, Conde-Knape, Karin, Konkar, Anish. Preparation and Characterization of Albumin Conjugates of a Truncated Peptide YY Analogue for Half-Life Extension. Bioconjugate chemistry, vol.24, no.12, 2015-2024.

  100. Conju Chem Curr Opin Investig Drugs Giannoukakis N 1245 4 10 2003 

  101. Kim, Jung-Guk, Baggio, Laurie L., Bridon, Dominique P., Castaigne, Jean-Paul, Robitaille, Martin F., Jetté, Lucie, Benquet, Corinne, Drucker, Daniel J.. Development and Characterization of a Glucagon-Like Peptide 1-Albumin Conjugate. Diabetes, vol.52, no.3, 751-759.

  102. Léger, Roger, Thibaudeau, Karen, Robitaille, Martin, Quraishi, Omar, van Wyk, Pieter, Bousquet-Gagnon, Nathalie, Carette, Julie, Castaigne, Jean-Paul, Bridon, Dominique P.. Identification of CJC-1131-albumin bioconjugate as a stable and bioactive GLP-1(7–36) analog. Bioorganic & medicinal chemistry letters, vol.14, no.17, 4395-4398.

  103. Baggio, L.L., Huang, Q., Cao, X., Drucker, D.J.. An Albumin-Exendin-4 Conjugate Engages Central and Peripheral Circuits Regulating Murine Energy and Glucose Homeostasis. Gastroenterology, vol.134, no.4, 1137-1147.

  104. 10.1002/9781118354599.ch10 

  105. Shi, Shuai, Liu, Jing, Joshi, Sangeeta B., Krasnoperov, Valery, Gill, Parkash, Middaugh, C. Russell, Volkin, David B.. Biophysical characterization and stabilization of the recombinant albumin fusion protein sEphB4–HSA. Journal of pharmaceutical sciences : a publication of the American Pharmaceutical Association, vol.101, no.6, 1969-1984.

  106. Cordes, Amanda A., Carpenter, John F., Randolph, Theodore W.. Selective domain stabilization as a strategy to reduce human serum albumin–human granulocyte colony stimulating factor aggregation rate. Journal of pharmaceutical sciences : a publication of the American Pharmaceutical Association, vol.101, no.6, 2009-2016.

  107. Cordes, Amanda A., Platt, Christopher W., Carpenter, John F., Randolph, Theodore W.. Selective domain stabilization as a strategy to reduce fusion protein aggregation. Journal of pharmaceutical sciences : a publication of the American Pharmaceutical Association, vol.101, no.4, 1400-1409.

  108. Rustgi, Vinod K.. Albinterferon alfa-2b, a novel fusion protein of human albumin and human interferon alfa-2b, for chronic hepatitis C. Current medical research and opinion : CMRO, vol.25, no.4, 991-1002.

  109. Patient Prefer Adherence Woodward HN 789 8 2014 

  110. Cousens, Leslie P., Najafian, Nader, Mingozzi, Federico, Elyaman, Wassim, Mazer, Bruce, Moise, Leonard, Messitt, Timothy J., Su, Yan, Sayegh, Mohamed, High, Katherine, Khoury, Samia J., Scott, David W., De Groot, Anne S.. In Vitro and In Vivo Studies of IgG-derived Treg Epitopes (Tregitopes): A Promising New Tool for Tolerance Induction and Treatment of Autoimmunity. Journal of clinical immunology, vol.33, no.suppl1, 43-49.

  111. 10.1586/1744666X.2013.858602 

  112. Sleep D. Veltis® - Engineered albumins for optimized drug dosing. 2014. Available from: http://www.slideshare.net/NiklasAndersson6/novozymes-veltis-an-innovative-platform-technology-for-the-half-life-extension-of-biotherapeutics-2014-april [Cited 9 December 2014] 

  113. Neumann, Elena, Frei, Eva, Funk, Dorothee, Becker, Matthias D, Schrenk, Hans-Hermann, Müller-Ladner, Ulf, Fiehn, Christoph. Native albumin for targeted drug delivery. Expert opinion on drug delivery, vol.7, no.8, 915-925.

  114. Yewale, Chetan, Baradia, Dipesh, Vhora, Imran, Misra, Ambikanandan. Proteins: emerging carrier for delivery of cancer therapeutics. Expert opinion on drug delivery, vol.10, no.10, 1429-1448.

  115. Kratz, F.. Albumin as a drug carrier: Design of prodrugs, drug conjugates and nanoparticles. Journal of controlled release : official journal of the Controlled Release Society, vol.132, no.3, 171-183.

  116. Stehle, Gerd, Sinn, Hannsjörg, Wunder, Andreas, Schrenk, Hans Hermann, Stewart, J.Charles M., Hartung, Gernot, Maier-Borst, Wolfgang, Heene, Dieter Ludwig. Plasma protein (albumin) catabolism by the tumor itself—implications for tumor metabolism and the genesis of cachexia. Critical reviews in oncology/hematology, vol.26, no.2, 77-100.

  117. Kratz, F.. A clinical update of using albumin as a drug vehicle - A commentary. Journal of controlled release : official journal of the Controlled Release Society, vol.190, 331-336.

  118. J Clin Invest Said N 751 123 2 2013 

  119. Cardone, Rosa A., Casavola, Valeria, Reshkin, Stephan J.. The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis. Nature reviews. Cancer, vol.5, no.10, 786-795.

  120. Neurol Res Kremer P 481 22 5 2000 10.1080/01616412.2000.11740705 

  121. Ding, Reinhard, Frei, Eva, Fardanesh, Mahmoudreza, Schrenk, Hans-Hermann, Kremer, Paul, Haefeli, Walter E.. Pharmacokinetics of 5-Aminofluorescein-Albumin, a Novel Fluorescence Marker of Brain Tumors During Surgery. The Journal of clinical pharmacology, vol.51, no.5, 672-678.

  122. Ishima, Yu, Chen, Di, Fang, Jun, Maeda, Hiroshi, Minomo, Ai, Kragh-Hansen, Ulrich, Kai, Toshiya, Maruyama, Toru, Otagiri, Masaki. S-NitrosatedHuman Serum AlbuminDimer is not only a Novel Anti-Tumor Drug but also a Potentiator forAnti-Tumor Drugs with Augmented EPR Effects. Bioconjugate chemistry, vol.23, no.2, 264-271.

  123. Ishima, Yu, Kragh-Hansen, Ulrich, Maruyama, Toru, Otagiri, Masaki. Poly- S -Nitrosated Albumin as a Safe and Effective Multifunctional Antitumor Agent: Characterization, Biochemistry and Possible Future Therapeutic Applications. BioMed research international, vol.2013, 353892-.

  124. Stehle, Gerd, Sinn, Hannsj??rg, Wunder, Andreas, Schrenk, Hans Herrmann, Sch??tt, Sandra, Maier-Borst, Wolfgang, Heene, Dieter Ludwig. The loading rate determines tumor targeting properties of methotrexate albumin conjugates in rats :. Anti-cancer drugs, vol.8, no.7, 667-685.

  125. Warnecke, André, Fichtner, Iduna, Saß, Gretel, Kratz, Felix. Synthesis, Cleavage Profile, and Antitumor Efficacy of an Albumin-Binding Prodrug of Methotrexate that is Cleaved by Plasmin and Cathepsin B. Archiv der Pharmazie, vol.340, no.8, 389-395.

  126. Fiehn, C, Kratz, F, Sass, G, Muller-Ladner, U, Neumann, E. Targeted drug delivery by in vivo coupling to endogenous albumin: an albumin-binding prodrug of methotrexate (MTX) is better than MTX in the treatment of murine collagen-induced arthritis. Annals of the rheumatic diseases : the official journal, vol.67, no.8, 1188-1191.

  127. Invest New Drugs Mita MM 2014 

  128. Singla, Anil K, Garg, Alka, Aggarwal, Deepika. Paclitaxel and its formulations. International journal of pharmaceutics, vol.235, no.1, 179-192.

  129. Gelderblom, H, Verweij, J, Nooter, K, Sparreboom, A. Cremophor EL : the drawbacks and advantages of vehicle selection for drug formulation. European journal of cancer, vol.37, no.13, 1590-1598.

  130. Socinski, Mark A., Bondarenko, Igor, Karaseva, Nina A., Makhson, Anatoly M., Vynnychenko, Igor, Okamoto, Isamu, Hon, Jeremy K., Hirsh, Vera, Bhar, Paul, Zhang, Hui, Iglesias, Jose L., Renschler, Markus F.. Weekly nab-Paclitaxel in Combination With Carboplatin Versus Solvent-Based Paclitaxel Plus Carboplatin as First-Line Therapy in Patients With Advanced Non-Small-Cell Lung Cancer: Final Results of a Phase III Trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol.30, no.17, 2055-2062.

  131. Lluch, A., Alvarez, I., Munoz, M., Segui, M.A., Tusquets, I., Garcia-Estevez, L.. Treatment innovations for metastatic breast cancer: Nanoparticle albumin-bound (NAB) technology targeted to tumors. Critical reviews in oncology/hematology, vol.89, no.1, 62-72.

  132. Al-Batran, Salah-Eddin, Geissler, Michael, Seufferlein, Thomas, Oettle, Helmut. Nab-Paclitaxel for Metastatic Pancreatic Cancer: Clinical Outcomes and Potential Mechanisms of Action. Oncology research and treatment, vol.37, no.3, 128-134.

  133. Cecco, Sara, Aliberti, Maria, Baldo, Paolo, Giacomin, Elisa, Leone, Roberto. Safety and efficacy evaluation of albumin-bound paclitaxel. Expert opinion on drug safety, vol.13, no.4, 511-520.

  134. Expert Opin Drug Saf Kudlowitz D 681 13 6 2014 

  135. Desai, Neil. Challenges in Development of Nanoparticle-Based Therapeutics. The AAPS journal, vol.14, no.2, 282-295.

  136. Li, C., Li, Y., Gao, Y., Wei, N., Zhao, X., Wang, C., Li, Y., Xiu, X., Cui, J.. Direct comparison of two albumin-based paclitaxel-loaded nanoparticle formulations: Is the crosslinked version more advantageous?. International journal of pharmaceutics, vol.468, no.1, 15-25.

  137. Bioconjug Chem Byeon HJ 2014 

  138. Liu, Mengyuan, Huang, Yi, Hu, Lei, Liu, Guoping, Hu, Xueping, Liu, Dongxu, Yang, Xiaosong. Selective delivery of interleukine-1 receptor antagonist to inflamed joint by albumin fusion. BMC biotechnology, vol.12, 68-68.

  139. Int J Nanomedicine Pang Z 3421 7 2012 

  140. Fiume, Luigi, Di Stefano, Giuseppina. Lactosaminated human albumin, a hepatotropic carrier of drugs. European journal of pharmaceutical sciences, vol.40, no.4, 253-262.

  141. Danhier, Fabienne, Le Breton, Aude, Préat, Véronique. RGD-Based Strategies To Target Alpha(v) Beta(3) Integrin in Cancer Therapy and Diagnosis. Molecular pharmaceutics, vol.9, no.11, 2961-2973.

  142. Temming, K., Meyer, D. L., Zabinski, R., Dijkers, E. C. F., Poelstra, K., Molema, G., Kok, R. J.. Evaluation of RGD-Targeted Albumin Carriers for Specific Delivery of Auristatin E to Tumor Blood Vessels. Bioconjugate chemistry, vol.17, no.6, 1385-1394.

  143. Temming, Kai., Meyer, Damon L., Zabinski, Roger., Senter, Peter D., Poelstra, Klaas., Molema, Grietje., Kok, Robbert J.. Improved Efficacy of αvβ3-Targeted Albumin Conjugates by Conjugation of a Novel Auristatin Derivative. Molecular pharmaceutics, vol.4, no.5, 686-694.

  144. Yazaki, P.J., Kassa, T., Cheung, C.w., Crow, D.M., Sherman, M.A., Bading, J.R., Anderson, A.L.J., Colcher, D., Raubitschek, A.. Biodistribution and tumor imaging of an anti-CEA single-chain antibody-albumin fusion protein. Nuclear medicine and biology, vol.35, no.2, 151-158.

  145. Bri J Cancer Huhalov A S63 91 2004 

  146. Altintas, I., Heukers, R., van der Meel, R., Lacombe, M., Amidi, M., van Bergen en Henegouwen, P.M.P., Hennink, W.E., Schiffelers, R.M., Kok, R.J.. Nanobody-albumin nanoparticles (NANAPs) for the delivery of a multikinase inhibitor 17864 to EGFR overexpressing tumor cells. Journal of controlled release : official journal of the Controlled Release Society, vol.165, no.2, 110-118.

  147. Ji, Shunrong, Xu, Jin, Zhang, Bo, Yao, Wantong, Xu, Wenyan, Wu, Wenzhe, Xu, Yongfeng, Wang, Hao, Ni, Quanxing, Hou, Huimin, Yu, Xianjun. RGD-conjugated albumin nanoparticles as a novel delivery vehicle in pancreatic cancer therapy.. Cancer biology & therapy, vol.13, no.4, 206-215.

  148. 10.1002/9781118354599.ch7 

  149. Pridgen, Eric M., Alexis, Frank, Kuo, Timothy T., Levy-Nissenbaum, Etgar, Karnik, Rohit, Blumberg, Richard S., Langer, Robert, Farokhzad, Omid C.. Transepithelial Transport of Fc-Targeted Nanoparticles by the Neonatal Fc Receptor for Oral Delivery. Science translational medicine, vol.5, no.213, 213ra167-213ra167.

  150. Ye, Lilin, Zeng, Rongyu, Bai, Yu, Roopenian, Derry C., Zhu, Xiaoping. Efficient Mucosal Delivery of Vaccine Using the FcRn-Mediated IgG Transfer Pathway. Nature biotechnology, vol.29, no.2, 158-163.

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