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Enhancement of cysteine catabolism into taurine impacts glutathione homeostasis in rats challenged with ethanol

Amino acids, v.47 no.6, 2015년, pp.1273 - 1277  

Ahn, Chul Won ,  Kwon, Do Young ,  Jun, Doo Sung ,  Lee, Yoo Min ,  Kim, Young Chul

Abstract AI-Helper 아이콘AI-Helper

We determined the alterations in metabolic conversion of cysteine into glutathione and taurine in liver of rats treated with ethanol acutely. Ethanol treatment reduced cysteine as well as glutathione levels in liver for 24 h. However, cysteine dioxygenase was up-regulated rapidly, and hypotaurine/ta...

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