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[해외논문] A mirror of two faces: Lin28 as a master regulator of both miRNA and mRNA

Wiley interdisciplinary reviews. RNA, v.3 no.4, 2012년, pp.483 - 494  

Huang, Yingqun

Abstract AI-Helper 아이콘AI-Helper

AbstractLin28 is an evolutionarily conserved RNA‐binding protein that plays important roles in development, pluripotency, tumorigenesis, and metabolism. Emerging evidence suggests that the pleiotropic roles of Lin28 in the diverse physiological and pathological processes are mechanistically l...

참고문헌 (72)

  1. Front Gene. Kallen AN 240 3 2012 10.3389/fgene.2012.00240 Does Lin28 antagonize miRNA‐mediated repression by displacing miRISC from target mRNAs? 

  2. Ambros, V, Horvitz, HR. Heterochronic mutants of the nematode Caenorhabditis elegans. Science, vol.226, no.4673, 409-416.

  3. Moss, Eric G, Lee, Rosalind C, Ambros, Victor. The Cold Shock Domain Protein LIN-28 Controls Developmental Timing in C. elegans and Is Regulated by the lin-4 RNA. Cell, vol.88, no.5, 637-646.

  4. Moss, E.G., Tang, L.. Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites. Developmental biology, vol.258, no.2, 432-442.

  5. Zhu, Hao, Shah, Samar, Shyh-Chang, Ng, Shinoda, Gen, Einhorn, William S, Viswanathan, Srinivas R, Takeuchi, Ayumu, Grasemann, Corinna, Rinn, John L, Lopez, Mary F, Hirschhorn, Joel N, Palmert, Mark R, Daley, George Q. Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies. Nature genetics, vol.42, no.7, 626-630.

  6. Darr, Henia, Benvenisty, Nissim. Genetic Analysis of the Role of the Reprogramming Gene LIN-28 in Human Embryonic Stem Cells. Stem cells®, vol.27, no.2, 352-362.

  7. Richards, Mark, Tan, Siew‐Peng, Tan, Jee‐Hian, Chan, Woon‐Khiong, Bongso, Ariff. The Transcriptome Profile of Human Embryonic Stem Cells as Defined by SAGE. Stem cells®, vol.22, no.1, 51-64.

  8. Heo, Inha, Joo, Chirlmin, Kim, Young-Kook, Ha, Minju, Yoon, Mi-Jeong, Cho, Jun, Yeom, Kyu-Hyeon, Han, Jinju, Kim, V. Narry. TUT4 in Concert with Lin28 Suppresses MicroRNA Biogenesis through Pre-MicroRNA Uridylation. Cell, vol.138, no.4, 696-708.

  9. Peng, Shuping, Chen, Ling-Ling, Lei, Xin-Xiang, Yang, Li, Lin, Haifan, Carmichael, Gordon G., Huang, Yingqun. Genome-Wide Studies Reveal That Lin28 Enhances the Translation of Genes Important for Growth and Survival of Human Embryonic Stem Cells. Stem cells®, vol.29, no.3, 496-504.

  10. Zhu, Hao, Shyh-Chang, Ng, Segrè, Ayellet V., Shinoda, Gen, Shah, Samar P., Einhorn, William S., Takeuchi, Ayumu, Engreitz, Jesse M., Hagan, John P., Kharas, Michael G., Urbach, Achia, Thornton, James E., Triboulet, Robinson, Gregory, Richard I., Altshuler, David, Daley, George Q.. The Lin28/let-7 Axis Regulates Glucose Metabolism. Cell, vol.147, no.1, 81-94.

  11. Viswanathan, Srinivas R., Powers, John T., Einhorn, William, Hoshida, Yujin, Ng, Tony, Toffanin, Sara, O'Sullivan, Maureen, Lu, Jun, Philips, Letha A., Lockhart, Victoria L., Shah, Samar P., Tanwar, Pradeep S., Mermel, Craig H., Beroukhim, Rameen, Azam, Mohammad, Teixeira, Jose, Meyerson, Matthew, Hughes, Timothy P., Llovet, Josep M, Radich, Jerald, Mullighan, Charles G., Golub, Todd R., Sorensen, Poul H., Daley, George Q.. Lin28 Enhances Tumorigenesis and is Associated With Advanced Human Malignancies. Nature genetics, vol.41, no.7, 843-848.

  12. Guo, Yingqiu, Chen, Yongxin, Ito, Hirotaka, Watanabe, Akira, Ge, Xijin, Kodama, Tatsuhiko, Aburatani, Hiroyuki. Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma. Gene, vol.384, 51-61.

  13. Lu, Lingeng, Katsaros, Dionyssios, Shaverdashvili, Khvaramze, Qian, Biyun, Wu, Yixing, de la Longrais, Irene A. Rigault, Preti, Mario, Menato, Guido, Yu, Herbert. Pluripotent factor lin-28 and its homologue lin-28b in epithelial ovarian cancer and their associations with disease outcomes and expression of let-7a and IGF-II. European journal of cancer, vol.45, no.12, 2212-2218.

  14. Peng, S, Maihle, N J, Huang, Y. Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer. Oncogene, vol.29, no.14, 2153-2159.

  15. King, Catrina E., Cuatrecasas, Miriam, Castells, Antoni, Sepulveda, Antonia R., Lee, Ju-Seog, Rustgi, Anil K.. LIN28B Promotes Colon Cancer Progression and Metastasis. Cancer research : the official organ of the American Association for Cancer Research, Inc, vol.71, no.12, 4260-4268.

  16. King, Catrina, Wang, Louise, Winograd, Rafael, Madison, Blair, Mongroo, Perry, Johnstone, Cameron, Rustgi, Anil K.. LIN28B fosters colon cancer migration, invasion, and transformation through let-7 dependent and independent mechanisms. Oncogene, vol.30, no.40, 4185-4193.

  17. Cao, Dengfeng, Allan, Robert W., Cheng, Liang, Peng, Yan, Guo, Charles C., Dahiya, Neha, Akhi, Shirin, Li, Jianping. RNA-binding protein LIN28 is a marker for testicular germ cell tumors. Human pathology, vol.42, no.5, 710-718.

  18. Ji, J., Wang, X.W.. A Yin-Yang balancing act of the lin28/let-7 link in tumorigenesis. Journal of hepatology : the journal of the European Association for the Study of the Liver, vol.53, no.5, 974-975.

  19. Yang, Xiaojun, Lin, Xiaojuan, Zhong, Xiaomin, Kaur, Sippy, Li, Ning, Liang, Shun, Lassus, Heini, Wang, Liping, Katsaros, Dionyssios, Montone, Kathleen, Zhao, Xia, Zhang, Youcheng, Bützow, Ralf, Coukos, George, Zhang, Lin. Double-Negative Feedback Loop between Reprogramming Factor LIN28 and microRNA let-7 Regulates Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells. Cancer research : the official organ of the American Association for Cancer Research, Inc, vol.70, no.22, 9463-9472.

  20. Newman, Martin A., Hammond, Scott M.. Emerging paradigms of regulated microRNA processing. Genes & development, vol.24, no.11, 1086-1092.

  21. Viswanathan, Srinivas R., Daley, George Q.. Lin28: A MicroRNA Regulator with a Macro Role. Cell, vol.140, no.4, 445-449.

  22. Lehrbach, Nicolas J, Miska, Eric A. Regulation of pre-miRNA Processing.. Advances in experimental medicine and biology, vol.700, 67-75.

  23. 10.4161/rna.4.1.4364 

  24. Rybak, Agnieszka, Fuchs, Heiko, Smirnova, Lena, Brandt, Christine, Pohl, Elena E., Nitsch, Robert, Wulczyn, F. Gregory. A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nature cell biology, vol.10, no.8, 987-993.

  25. Qiu, Caihong, Ma, Yinghong, Wang, Jianquan, Peng, Shuping, Huang, Yingqun. Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells. Nucleic acids research, vol.38, no.4, 1240-1248.

  26. Piskounova, E., Polytarchou, C., Thornton, James E., LaPierre, Robert J., Pothoulakis, C., Hagan, John P., Iliopoulos, D., Gregory, Richard I.. Lin28A and Lin28B Inhibit let-7 MicroRNA Biogenesis by Distinct Mechanisms. Cell, vol.147, no.5, 1066-1079.

  27. Viswanathan, Srinivas R., Daley, George Q., Gregory, Richard I.. Selective Blockade of MicroRNA Processing by Lin28. Science, vol.320, no.5872, 97-100.

  28. Newman, Martin A., Thomson, J. Michael, Hammond, Scott M.. Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. RNA, vol.14, no.8, 1539-1549.

  29. Heo, Inha, Joo, Chirlmin, Cho, Jun, Ha, Minju, Han, Jinju, Kim, V. Narry. Lin28 Mediates the Terminal Uridylation of let-7 Precursor MicroRNA. Molecular cell, vol.32, no.2, 276-284.

  30. Piskounova, Elena, Viswanathan, Srinivas R., Janas, Maja, LaPierre, Robert J., Daley, George Q., Sliz, Piotr, Gregory, Richard I.. Determinants of MicroRNA Processing Inhibition by the Developmentally Regulated RNA-binding Protein Lin28. The Journal of biological chemistry, vol.283, no.31, 21310-21314.

  31. Thomson, J. Michael, Newman, Martin, Parker, Joel S., Morin-Kensicki, Elizabeth M., Wright, Tricia, Hammond, Scott M.. Extensive post-transcriptional regulation of microRNAs and its implications for cancer. Genes & development, vol.20, no.16, 2202-2207.

  32. Suh, Mi-Ra, Lee, Yoontae, Kim, Jung Yeon, Kim, Soo-Kyoung, Moon, Sung-Hwan, Lee, Ji Yeon, Cha, Kwang-Yul, Chung, Hyung Min, Yoon, Hyun Soo, Moon, Shin Yong, Kim, V.Narry, Kim, Kye-Seong. Human embryonic stem cells express a unique set of microRNAs. Developmental biology, vol.270, no.2, 488-498.

  33. Wulczyn, F. Gregory, Smirnova, Lena, Rybak, Agnieszka, Brandt, Christine, Kwidzinski, Erik, Ninnemann, Olaf, Strehle, Michael, Seiler, Andrea, Schumacher, Stefan, Nitsch, Robert. Retracted: Post‐transcriptional regulation of the let‐7 microRNA during neural cell specification. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol.21, no.2, 415-426.

  34. Van Wynsberghe, Priscilla M., Kai, Zoya S., Massirer, Katlin B., Burton, Victoria H., Yeo, Gene W., Pasquinelli, Amy E.. LIN-28 co-transcriptionally binds primary let-7 to regulate miRNA maturation in C. elegans. Nature structural & molecular biology, vol.18, no.3, 302-308.

  35. Morlando, Mariangela, Ballarino, Monica, Gromak, Natalia, Pagano, Francesca, Bozzoni, Irene, Proudfoot, Nick J. Primary microRNA transcripts are processed co-transcriptionally. Nature structural & molecular biology, vol.15, no.9, 902-909.

  36. Pawlicki, Jan M., Steitz, Joan A.. Nuclear networking fashions pre-messenger RNA and primary microRNA transcripts for function. Trends in cell biology, vol.20, no.1, 52-61.

  37. Hagan, John P., Piskounova, Elena, Gregory, Richard I.. Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in embryonic stem cells. Nature structural & molecular biology, vol.16, no.10, 1021-1025.

  38. Lehrbach, Nicolas J., Armisen, Javier, Lightfoot, Helen L., Murfitt, Kenneth J., Bugaut, Anthony, Balasubramanian, Shankar, Miska, Eric A.. LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans. Nature structural & molecular biology, vol.16, no.10, 1016-1020.

  39. Trabucchi, Michele, Briata, Paola, Garcia-Mayoral, MariaFlor, Haase, Astrid D., Filipowicz, Witold, Ramos, Andres, Gherzi, Roberto, Rosenfeld, Michael G.. The RNA-binding Protein KSRP Promotes the Biogenesis of a Subset of miRNAs. Nature, vol.459, no.7249, 1010-1014.

  40. Lightfoot, HelenL., Bugaut, Anthony, Armisen, Javier, Lehrbach, NicolasJ., Miska, Eric A., Balasubramanian, Shankar. A LIN28-Dependent StructuralChange in pre-let-7g Directly Inhibits Dicer Processing. Biochemistry, vol.50, no.35, 7514-7521.

  41. Desjardins, Alexandre, Yang, Ao, Bouvette, Jonathan, Omichinski, James G., Legault, Pascale. Importance of the NCp7-like domain in the recognition of pre-let-7g by the pluripotency factor Lin28. Nucleic acids research, vol.40, no.4, 1767-1777.

  42. Nam, Y., Chen, C., Gregory, Richard I., Chou, James J., Sliz, P.. Molecular Basis for Interaction of let-7 MicroRNAs with Lin28. Cell, vol.147, no.5, 1080-1091.

  43. Michlewski, Gracjan, Cáceres, Javier F.. Antagonistic role of hnRNP A1 and KSRP in the regulation of Let-7a biogenesis. Nature structural & molecular biology, vol.17, no.8, 1011-1018.

  44. Büssing, Ingo, Slack, Frank J., Großhans, Helge. let-7 microRNAs in development, stem cells and cancer. Trends in molecular medicine, vol.14, no.9, 400-409.

  45. 10.1186/gb-2004-5-3-r13 

  46. Wu, Ligang, Belasco, Joel G.. Micro-RNA Regulation of the Mammalian lin-28 Gene during Neuronal Differentiation of Embryonal Carcinoma Cells. Molecular and cellular biology, vol.25, no.21, 9198-9208.

  47. Lettre, Guillaume. Recent progress in the study of the genetics of height. Human genetics, vol.129, no.5, 465-472.

  48. Trumpp, Andreas, Refaeli, Yosef, Oskarsson, Thordur, Gasser, Stephan, Murphy, Mark, Martin, Gail R., Bishop, J. Michael. c-Myc regulates mammalian body size by controlling cell number but not cell size. Nature, vol.414, no.6865, 768-773.

  49. Weedon, Michael N, Lettre, Guillaume, Freathy, Rachel M, Lindgren, Cecilia M, Voight, Benjamin F, Perry, John R B, Elliott, Katherine S, Hackett, Rachel, Guiducci, Candace, Shields, Beverley, Zeggini, Eleftheria, Lango, Hana, Lyssenko, Valeriya, Timpson, Nicholas J, Burtt, Noel P, Rayner, Nigel W, Saxena, Richa, Ardlie, Kristin, Tobias, Jonathan H, Ness, Andrew R, Ring, Susan M, Palmer, Colin N A, Morris, Andrew D, Peltonen, Leena, Salomaa, Veikko, Smith, George Davey, Groop, Leif C, Hattersley, Andrew T, McCarthy, Mark I, Hirschhorn, Joel N, Frayling, Timothy M. A common variant of HMGA2 is associated with adult and childhood height in the general population. Nature genetics, vol.39, no.10, 1245-1250.

  50. Mol Cell Biol Hansen TV 4448 24 2004 10.1128/MCB.24.10.4448-4464.2004 Dwarfism and impaired gut development in insulin‐like growth factor II mRNA‐binding protein 1‐deficient mice. 

  51. Yang, Dong-Hua, Moss, Eric G.. Temporally regulated expression of Lin-28 in diverse tissues of the developing mouse. Gene expression patterns : GEP, vol.3, no.6, 719-726.

  52. Chang, Tsung-Cheng, Zeitels, Lauren R., Hwang, Hun-Way, Chivukula, Raghu R., Wentzel, Erik A., Dews, Michael, Jung, Jason, Gao, Ping, Dang, Chi V., Beer, Michael A., Thomas-Tikhonenko, Andrei, Mendell, Joshua T.. Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation. Proceedings of the National Academy of Sciences of the United States of America, vol.106, no.9, 3384-3389.

  53. Dangi-Garimella, Surabhi, Yun, Jieun, Eves, Eva M, Newman, Martin, Erkeland, Stefan J, Hammond, Scott M, Minn, Andy J, Rosner, Marsha Rich. Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7. The EMBO journal, vol.28, no.4, 347-358.

  54. Iliopoulos, Dimitrios, Hirsch, Heather A., Struhl, Kevin. An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation. Cell, vol.139, no.4, 693-706.

  55. Roush, Sarah, Slack, Frank J.. The let-7 family of microRNAs. Trends in cell biology, vol.18, no.10, 505-516.

  56. Polesskaya, Anna, Cuvellier, Sylvain, Naguibneva, Irina, Duquet, Arnaud, Moss, Eric G., Harel-Bellan, Annick. Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency. Genes & development, vol.21, no.9, 1125-1138.

  57. Yu, Junying, Vodyanik, Maxim A., Smuga-Otto, Kim, Antosiewicz-Bourget, Jessica, Frane, Jennifer L., Tian, Shulan, Nie, Jeff, Jonsdottir, Gudrun A., Ruotti, Victor, Stewart, Ron, Slukvin, Igor I., Thomson, James A.. Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells. Science, vol.318, no.5858, 1917-1920.

  58. Melton, Collin, Judson, Robert, Blelloch, Robert. Opposing microRNA families regulate self-renewal in mouse embryonic stem cells. Nature, vol.463, no.7281, 621-626.

  59. Zhong, Xiaomin, Li, Ning, Liang, Shun, Huang, Qihong, Coukos, George, Zhang, Lin. Identification of MicroRNAs Regulating Reprogramming Factor LIN28 in Embryonic Stem Cells and Cancer Cells. The Journal of biological chemistry, vol.285, no.53, 41961-41971.

  60. Balzer, Erica, Heine, Christian, Jiang, Qiang, Lee, Vivian M., Moss, Eric G.. LIN28 alters cell fate succession and acts independently of the let-7 microRNA during neurogliogenesis in vitro. Development, vol.137, no.6, 891-900.

  61. Xu, Bingsen, Zhang, Kexiong, Huang, Yingqun. Lin28 modulates cell growth and associates with a subset of cell cycle regulator mRNAs in mouse embryonic stem cells. RNA, vol.15, no.3, 357-361.

  62. Xu, Bingsen, Huang, Yingqun. Histone H2a mRNA interacts with Lin28 and contains a Lin28-dependent posttranscriptional regulatory element. Nucleic acids research, vol.37, no.13, 4256-4263.

  63. Pei, Duanqing. Regulation of Pluripotency and Reprogramming by Transcription Factors. The Journal of biological chemistry, vol.284, no.6, 3365-3369.

  64. Hanna, Jacob, Saha, Krishanu, Pando, Bernardo, van Zon, Jeroen, Lengner, Christopher J., Creyghton, Menno P., van Oudenaarden, Alexander, Jaenisch, Rudolf. Direct cell reprogramming is a stochastic process amenable to acceleration. Nature, vol.462, no.7273, 595-601.

  65. Nucleic Acids Res Lei XX 2011 Determinants of mRNA recognition and translation regulation by Lin28. 

  66. Jin, Jianyu, Jing, Wei, Lei, Xin-Xiang, Feng, Chen, Peng, Shuping, Boris-Lawrie, Kathleen, Huang, Yingqun. Evidence that Lin28 stimulates translation by recruiting RNA helicase A to polysomes. Nucleic acids research, vol.39, no.9, 3724-3734.

  67. Bleichert, Franziska, Baserga, Susan J.. The Long Unwinding Road of RNA Helicases. Molecular cell, vol.27, no.3, 339-352.

  68. Linder, Patrick, Jankowsky, Eckhard. From unwinding to clamping ?? the DEAD box RNA helicase family. Nature reviews. Molecular cell biology, vol.12, no.8, 505-516.

  69. Hartman, Tiffiney Roberts, Qian, Shuiming, Bolinger, Cheryl, Fernandez, Soledad, Schoenberg, Daniel R, Boris-Lawrie, Kathleen. RNA helicase A is necessary for translation of selected messenger RNAs. Nature structural & molecular biology, vol.13, no.6, 509-516.

  70. Roberts, Tiffiney M., Boris-Lawrie, Kathleen. Primary Sequence and Secondary Structure Motifs in Spleen Necrosis Virus RU5 Confer Translational Utilization of Unspliced Human Immunodeficiency Virus Type 1 Reporter RNA. Journal of virology, vol.77, no.22, 11973-11984.

  71. Bolinger, Cheryl, Sharma, Amit, Singh, Deepali, Yu, Lianbo, Boris-Lawrie, Kathleen. RNA helicase A modulates translation of HIV-1 and infectivity of progeny virions. Nucleic acids research, vol.38, no.5, 1686-1696.

  72. Marintchev, Assen, Edmonds, Katherine A., Marintcheva, Boriana, Hendrickson, Elthea, Oberer, Monika, Suzuki, Chikako, Herdy, Barbara, Sonenberg, Nahum, Wagner, Gerhard. Topology and Regulation of the Human eIF4A/4G/4H Helicase Complex in Translation Initiation. Cell, vol.136, no.3, 447-460.

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