$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Moonlighting proteins in cancer 원문보기

Cancer letters, v.370 no.1, 2016년, pp.108 - 116  

Min, K.W. ,  Lee, S.H. ,  Baek, S.J.

Abstract AI-Helper 아이콘AI-Helper

Since the 1980s, growing evidence suggested that the cellular localization of proteins determined their activity and biological functions. In a classical view, a protein is characterized by the single cellular compartment where it primarily resides and functions. It is now believed that when protein...

주제어

참고문헌 (129)

  1. BMC Bioinformatics Parras-Molto 14 229 2013 10.1186/1471-2105-14-229 Classification of protein motifs based on subcellular localization uncovers evolutionary relationships at both sequence and functional levels 

  2. Trends Biochem. Sci Jeffery 24 8 1999 10.1016/S0968-0004(98)01335-8 Moonlighting proteins 

  3. Trends Genet Jeffery 19 415 2003 10.1016/S0168-9525(03)00167-7 Moonlighting proteins: old proteins learning new tricks 

  4. Biochim. Biophys. Acta Huberts 1803 520 2010 10.1016/j.bbamcr.2010.01.022 Moonlighting proteins: an intriguing mode of multitasking 

  5. Mol. Biosyst Jeffery 5 345 2009 10.1039/b900658n Moonlighting proteins-an update 

  6. Cancer Cell Isaacs 3 213 2003 10.1016/S1535-6108(03)00029-1 Heat shock protein 90 as a molecular target for cancer therapeutics 

  7. Nat. Rev. Cancer Whitesell 5 761 2005 10.1038/nrc1716 HSP90 and the chaperoning of cancer 

  8. Proc. Natl. Acad. Sci. U. S. A. Wang 106 21288 2009 10.1073/pnas.0908151106 The regulatory mechanism of Hsp90α secretion and its function in tumor malignancy 

  9. Nat. Cell Biol Eustace 6 507 2004 10.1038/ncb1131 Functional proteomic screens reveal an essential extracellular role for hsp90[alpha] in cancer cell invasiveness 

  10. J. Biol. Chem Song 285 40039 2010 10.1074/jbc.M110.181941 The regulatory mechanism of extracellular Hsp90α on matrix metalloproteinase-2 processing and tumor angiogenesis 

  11. J. Biol. Chem Hance 287 37732 2012 10.1074/jbc.M112.389015 Secreted Hsp90 is a novel regulator of the epithelial to mesenchymal transition (EMT) in prostate cancer 

  12. Pharmacol. Ther Csermely 79 129 1998 10.1016/S0163-7258(98)00013-8 The 90-kDa molecular chaperone family: structure, function, and clinical applications. A comprehensive review 

  13. Nat. Rev. Cancer Trepel 10 537 2010 10.1038/nrc2887 Targeting the dynamic HSP90 complex in cancer 

  14. Biochim. Biophys. Acta Jhaveri 2012 742 1823 Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers 

  15. Curr. Opin. Investig. Drugs Wang 11 1466 2010 STA-9090, a small-molecule Hsp90 inhibitor for the potential treatment of cancer 

  16. Nat. Rev. Mol. Cell Biol Lorand 4 140 2003 10.1038/nrm1014 Transglutaminases: crosslinking enzymes with pleiotropic functions 

  17. Amino Acids Park 39 619 2010 10.1007/s00726-010-0500-z Transglutaminase 2: a multi-functional protein in multiple subcellular compartments 

  18. Carcinogenesis Cao 29 1893 2008 10.1093/carcin/bgn158 Tissue transglutaminase protects epithelial ovarian cancer cells from cisplatin-induced apoptosis by promoting cell survival signaling 

  19. J. Biol. Chem Iismaa 275 18259 2000 10.1074/jbc.M000583200 GTP binding and signaling by Gh/transglutaminase II involves distinct residues in a unique GTP-binding pocket 

  20. J. Biol. Chem Mishra 279 23863 2004 10.1074/jbc.M311919200 Tissue transglutaminase has intrinsic kinase activity: identification of transglutaminase 2 as an insulin-like growth factor-binding protein-3 kinase 

  21. J. Biol. Chem Lesort 273 11991 1998 10.1074/jbc.273.20.11991 Distinct nuclear localization and activity of tissue transglutaminase 

  22. Cancer Res Mann 66 8788 2006 10.1158/0008-5472.CAN-06-1457 Overexpression of tissue transglutaminase leads to constitutive activation of nuclear factor-κB in cancer cells: delineation of a novel pathway 

  23. FEBS Lett Peng 446 35 1999 10.1016/S0014-5793(99)00018-6 Interaction of tissue transglutaminase with nuclear transport protein importin-α3 

  24. Mol. Cell. Biol Oliverio 17 6040 1997 10.1128/MCB.17.10.6040 Tissue transglutaminase-dependent posttranslational modification of the retinoblastoma gene product in promonocytic cells undergoing apoptosis 

  25. FASEB J. Filiano 22 2662 2008 10.1096/fj.07-097709 Transglutaminase 2 protects against ischemic insult, interacts with HIF1β, and attenuates HIF1 signaling 

  26. Gastroenterology Tatsukawa 136 1783 2009 10.1053/j.gastro.2009.01.007 Role of transglutaminase 2 in liver injury via cross-linking and silencing of transcription factor Sp1 

  27. J. Biol. Chem Mishra 281 5532 2006 10.1074/jbc.M506864200 Phosphorylation of histones by tissue transglutaminase 

  28. Amino Acids Collighan 36 659 2009 10.1007/s00726-008-0190-y Transglutaminase 2 cross-linking of matrix proteins: biological significance and medical applications 

  29. Blood Akimov 98 1567 2001 10.1182/blood.V98.5.1567 Cell surface tissue transglutaminase is involved in adhesion and migration of monocytic cells on fibronectin 

  30. J. Biol. Chem Telci 283 20937 2008 10.1074/jbc.M801763200 Fibronectin-tissue transglutaminase matrix rescues RGD-impaired cell adhesion through syndecan-4 and β1 integrin Co-signaling 

  31. PLoS ONE Yakubov 9 e89285 2014 10.1371/journal.pone.0089285 Small molecule inhibitors target the tissue transglutaminase and fibronectin interaction 

  32. J. Cell. Biochem Sirover 113 2193 2012 10.1002/jcb.24113 Subcellular dynamics of multifunctional protein regulation: mechanisms of GAPDH intracellular translocation 

  33. Cell. Signal Tristan 23 317 2011 10.1016/j.cellsig.2010.08.003 The diverse functions of GAPDH: views from different subcellular compartments 

  34. Nat. Cell Biol Hara 7 665 2005 10.1038/ncb1268 S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding 

  35. Nat. Cell Biol Sen 10 866 2008 10.1038/ncb1747 Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis 

  36. J. Biol. Chem Azam 283 30632 2008 10.1074/jbc.M801401200 Human glyceraldehyde-3-phosphate dehydrogenase plays a direct role in reactivating oxidized forms of the DNA repair enzyme APE1 

  37. J. Biol. Chem Dai 283 26894 2008 10.1074/jbc.M804307200 Histone 2B (H2B) expression is confined to a proper NAD+/NADH redox status 

  38. J. Mol. Biol Demarse 394 789 2009 10.1016/j.jmb.2009.09.062 Direct binding of glyceraldehyde 3-phosphate dehydrogenase to telomeric DNA protects telomeres against chemotherapy-induced rapid degradation 

  39. J. Neurochem Chou 77 120 2001 10.1046/j.1471-4159.2001.t01-1-00209.x Identity of nuclear high-mobility-group protein, HMG-1, and sulfoglucuronyl carbohydrate-binding protein, SBP-1, in brain 

  40. Curr. Opin. Genet. Dev Bianchi 15 496 2005 10.1016/j.gde.2005.08.007 HMG proteins: dynamic players in gene regulation and differentiation 

  41. Nat. Rev. Immunol Lotze 5 331 2005 10.1038/nri1594 High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal 

  42. Science Wang 285 248 1999 10.1126/science.285.5425.248 HMG-1 as a late mediator of endotoxin lethality in mice 

  43. Immunol. Cell Biol Diener 91 443 2013 10.1038/icb.2013.25 The multifunctional alarmin HMGB1 with roles in the pathophysiology of sepsis and cancer 

  44. Annu. Rev. Immunol Sims 28 367 2010 10.1146/annurev.immunol.021908.132603 HMGB1 and RAGE in inflammation and cancer 

  45. Pathol. Int Abe 64 267 2014 10.1111/pin.12167 High Mobility Group Box 1 (HMGB1) released from cancer cells induces the expression of pro-inflammatory cytokines in peritoneal fibroblasts 

  46. Cell Kruse 137 609 2009 10.1016/j.cell.2009.04.050 Modes of p53 regulation 

  47. Nat. Rev. Mol. Cell Biol Riley 9 402 2008 10.1038/nrm2395 Transcriptional control of human p53-regulated genes 

  48. Science Chipuk 309 1732 2005 10.1126/science.1114297 PUMA couples the nuclear and cytoplasmic proapoptotic function of p53 

  49. Proc. Natl. Acad. Sci. U. S. A. You 103 9051 2006 10.1073/pnas.0600889103 Regulation of transactivation-independent proapoptotic activity of p53 by FOXO3a 

  50. EMBO J. Marchenko 26 923 2007 10.1038/sj.emboj.7601560 Monoubiquitylation promotes mitochondrial p53 translocation 

  51. Science Chipuk 303 1010 2004 10.1126/science.1092734 Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis 

  52. Nature Green 458 1127 2009 10.1038/nature07986 Cytoplasmic functions of the tumour suppressor p53 

  53. Proc. Natl. Acad. Sci. U.S.A. Foo 104 20826 2007 10.1073/pnas.0710017104 Regulation of p53 tetramerization and nuclear export by ARC 

  54. Curr. Med. Chem Lv 22 618 2015 10.2174/0929867322666141128162557 Recent advances of p53-MDM2 small molecule inhibitors (2011-present) 

  55. J. Med. Chem Zhao 58 1038 2015 10.1021/jm501092z Small-molecule inhibitors of the MDM2-p53 protein-protein interaction (MDM2 inhibitors) in clinical trials for cancer treatment 

  56. J. Biol. Chem Rudders 276 3302 2001 10.1074/jbc.M006507200 ESE-1 is a novel transcriptional mediator of inflammation that interacts with NF-kappa B to regulate the inducible nitric-oxide synthase gene 

  57. FEBS J. Grall 272 1676 2005 10.1111/j.1742-4658.2005.04592.x The Ets transcription factor ESE-1 mediates induction of the COX-2 gene by LPS in monocytes 

  58. J. Biol. Chem Choi 273 110 1998 10.1074/jbc.273.1.110 A novel ets-related transcription factor, ERT/ESX/ESE-1, regulates expression of the transforming growth factor-beta type II receptor 

  59. Oncogene Park 20 1235 2001 10.1038/sj.onc.1204227 Sequence-specific enhancer binding protein is responsible for the differential expression of ERT/ESX/ELF-3/ESE-1/jen gene in human gastric cancer cell lines: implication for the loss of TGF-beta type II receptor expression 

  60. Open Cancer J. Walker 3 77 2010 10.2174/1874079001003010077 ESE-1 is required to maintain the transformed phenotype of MCF-7 and ZR-75-1 human breast cancer cells 

  61. Cell Death Dis Wang 5 e1263 2014 10.1038/cddis.2014.206 Elf3 drives beta-catenin transactivation and associates with poor prognosis in colorectal cancer 

  62. Cancer Res Longoni 73 4533 2013 10.1158/0008-5472.CAN-12-4537 ETS transcription factor ESE1/ELF3 orchestrates a positive feedback loop that constitutively activates NF-kappaB and drives prostate cancer progression 

  63. J. Biol. Chem Manavathi 282 19820 2007 10.1074/jbc.M702309200 Phosphorylation-dependent regulation of stability and transforming potential of ETS transcriptional factor ESE-1 by p21-activated kinase 1 

  64. Oncogene Shatnawi 33 862 2014 10.1038/onc.2013.15 ELF3 is a repressor of androgen receptor action in prostate cancer cells 

  65. Oncogene Chang 19 151 2000 10.1038/sj.onc.1203252 Over-expression of ERT(ESX/ESE-1/ELF3), an ets-related transcription factor, induces endogenous TGF-beta type II receptor expression and restores the TGF-beta signaling pathway in Hs578t human breast cancer cells 

  66. Mol. Cell. Biol Prescott 24 5548 2004 10.1128/MCB.24.12.5548-5564.2004 The ETS transcription factor ESE-1 transforms MCF-12A human mammary epithelial cells via a novel cytoplasmic mechanism 

  67. Mol. Cancer Ther Lee 7 3739 2008 10.1158/1535-7163.MCT-08-0548 ESE-1/EGR-1 pathway plays a role in tolfenamic acid-induced apoptosis in colorectal cancer cells 

  68. Nature Reya 434 843 2005 10.1038/nature03319 Wnt signalling in stem cells and cancer 

  69. Proc. Natl. Acad. Sci. U. S. A. Sanchez-Tillo 108 19204 2011 10.1073/pnas.1108977108 β-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness 

  70. Proc. Natl. Acad. Sci. U. S. A. Smith 99 9433 2002 10.1073/pnas.122612899 Mutations in APC, Kirsten-ras, and p53 - alternative genetic pathways to colorectal cancer 

  71. EMBO J. Polakis 31 2737 2012 10.1038/emboj.2012.126 Drugging Wnt signalling in cancer 

  72. EMBO J. Valenta 31 2714 2012 10.1038/emboj.2012.150 The many faces and functions of [beta]-catenin 

  73. Nat. Rev. Cancer Martin-Belmonte 12 23 2012 10.1038/nrc3169 Epithelial cell polarity, stem cells and cancer 

  74. Cancer Res Jang 75 1691 2015 10.1158/0008-5472.CAN-14-2041 Wnt/β-catenin small-molecule inhibitor CWP232228 preferentially inhibits the growth of breast cancer stem-like cells 

  75. Cell Kessenbrock 141 52 2010 10.1016/j.cell.2010.03.015 Matrix metalloproteinases: regulators of the tumor microenvironment 

  76. Nat. Rev. Mol. Cell Biol Page-McCaw 8 221 2007 10.1038/nrm2125 Matrix metalloproteinases and the regulation of tissue remodelling 

  77. Prog. Histochem. Cytochem Mannello 47 27 2012 10.1016/j.proghi.2011.12.002 Nuclear localization of Matrix metalloproteinases 

  78. FASEB J. Kwan 18 690 2004 10.1096/fj.02-1202fje Matrix metalloproteinase-2 (MMP-2) is present in the nucleus of cardiac myocytes and is capable of cleaving poly (ADP-ribose) polymerase (PARP) in vitro 

  79. Am. J. Pathol Si-Tayeb 169 1390 2006 10.2353/ajpath.2006.060005 Matrix metalloproteinase 3 is present in the cell nucleus and is involved in apoptosis 

  80. Mol. Cell. Biol Eguchi 28 2391 2008 10.1128/MCB.01288-07 Novel transcription factor-like function of human matrix metalloproteinase 3 regulating the CTGF/CCN2 gene 

  81. Nat. Med Marchant 20 493 2014 10.1038/nm.3508 A new transcriptional role for matrix metalloproteinase-12 in antiviral immunity 

  82. Mol. Pharmacol Baek 59 901 2001 10.1124/mol.59.4.901 Cyclooxygenase inhibitors regulate the expression of a TGF-beta superfamily member that has proapoptotic and antitumorigenic activities 

  83. Proc. Natl. Acad. Sci. U.S.A. Bootcov 94 11514 1997 10.1073/pnas.94.21.11514 MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily 

  84. Carcinogenesis Baek 23 425 2002 10.1093/carcin/23.3.425 Resveratrol enhances the expression of non-steroidal anti-inflammatory drug-activated gene (NAG-1) by increasing the expression of p53 

  85. Oncogene Albertoni 21 4212 2002 10.1038/sj.onc.1205610 Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1 

  86. Sci. Rep Tsui 5 12870 2015 10.1038/srep12870 Growth differentiation factor-15: a p53- and demethylation-upregulating gene represses cell proliferation, invasion, and tumorigenesis in bladder carcinoma cells 

  87. Br. J. Cancer Nakamura 88 1101 2003 10.1038/sj.bjc.6600869 Quantitative analysis of macrophage inhibitory cytokine-1 (MIC-1) gene expression in human prostatic tissues 

  88. Oncogene Senapati 29 1293 2010 10.1038/onc.2009.420 Overexpression of macrophage inhibitory cytokine-1 induces metastasis of human prostate cancer cells through the FAK-RhoA signaling pathway 

  89. Gastroenterology Baek 131 1553 2006 10.1053/j.gastro.2006.09.015 Nonsteroidal anti-inflammatory drug-activated gene-1 over expression in transgenic mice suppresses intestinal neoplasia 

  90. Mol. Pharmacol Chintharlapalli 68 1782 2005 10.1124/mol.105.017046 

  91. Mol. Carcinog Jutooru 48 692 2009 10.1002/mc.20518 Induction of apoptosis and nonsteroidal anti-inflammatory drug-activated gene 1 in pancreatic cancer cells by a glycyrrhetinic acid derivative 

  92. Cancer Lett Kelly 277 38 2009 10.1016/j.canlet.2008.11.013 p53 controls prostate-derived factor/macrophage inhibitory cytokine/NSAID-activated gene expression in response to cell density, DNA damage and hypoxia through diverse mechanisms 

  93. Mol. Cancer Ther Yang 2 1023 2003 Macrophage inhibitory cytokine-1: a novel biomarker for p53 pathway activation 

  94. Cancer Prev. Res. (Phila.) Cekanova 2 450 2009 10.1158/1940-6207.CAPR-09-0057 Nonsteroidal anti-inflammatory drug-activated gene-1 expression inhibits urethane-induced pulmonary tumorigenesis in transgenic mice 

  95. J. Cancer Res. Clin. Oncol Zimmers 136 571 2010 10.1007/s00432-009-0691-4 Loss of GDF-15 abolishes sulindac chemoprevention in the ApcMin/+ mouse model of intestinal cancer 

  96. Biochem. Pharmacol Wang 85 597 2013 10.1016/j.bcp.2012.11.025 The diverse roles of nonsteroidal anti-inflammatory drug activated gene (NAG-1/GDF15) in cancer 

  97. Int. J. Obes. (Lond) Chrysovergis 38 1555 2014 10.1038/ijo.2014.27 NAG-1/GDF-15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism 

  98. Oncogene Min 2015 10.1038/onc.2015.95 NAG-1/GDF15 Accumulates in the nucleus and modulates transcriptional regulation of the Smad pathway 

  99. Nat. Rev. Mol. Cell Biol Gumbiner 6 622 2005 10.1038/nrm1699 Regulation of cadherin-mediated adhesion in morphogenesis 

  100. Gene Dev Halbleib 20 3199 2006 10.1101/gad.1486806 Cadherins in development: cell adhesion, sorting, and tissue morphogenesis 

  101. EMBO J. Qian 23 8 1739 2004 10.1038/sj.emboj.7600136 E-cadherin-mediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases 

  102. Nat. Rev. Cancer Polyak 9 265 2009 10.1038/nrc2620 Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits 

  103. Mol. Cancer Res Yilmaz 8 629 2010 10.1158/1541-7786.MCR-10-0139 Mechanisms of motility in metastasizing cells 

  104. J. Biol. Chem Ferber 283 12691 2008 10.1074/jbc.M708887200 A role for the cleaved cytoplasmic domain of E-cadherin in the nucleus 

  105. Am. J. Surg. Pathol Chetty 32 413 2008 10.1097/PAS.0b013e31813547f8 Loss of membrane localization and aberrant nuclear E-cadherin expression correlates with invasion in pancreatic endocrine tumors 

  106. Cancer Res David 72 2917 2012 10.1158/0008-5472.CAN-11-3498 Dishonorable discharge: the oncogenic roles of cleaved E-cadherin fragments 

  107. Exp. Cell Res Inge 317 838 2011 10.1016/j.yexcr.2010.12.025 Soluble E-cadherin promotes cell survival by activating epidermal growth factor receptor 

  108. Cell Shi 113 685 2003 10.1016/S0092-8674(03)00432-X Mechanisms of TGF-β signaling from cell membrane to the nucleus 

  109. Mol. Cell Liu 35 26 2009 10.1016/j.molcel.2009.06.018 TACE-mediated ectodomain shedding of the type I TGF-β receptor downregulates TGF-β signaling 

  110. Nat. Commun Mu 2 330 2011 10.1038/ncomms1332 TRAF6 ubiquitinates TGF[beta] type I receptor to promote its cleavage and nuclear translocation in cancer 

  111. Mol. Cell. Biol Chandra 32 2183 2012 10.1128/MCB.00320-12 Nuclear translocation of type I transforming growth factor β receptor confers a novel function in RNA processing 

  112. Nat. Cell Biol Lin 3 802 2001 10.1038/ncb0901-802 Nuclear localization of EGF receptor and its potential new role as a transcription factor 

  113. Cancer Cell Xu 27 177 2015 10.1016/j.ccell.2014.11.025 14-3-3ζ turns TGF-β's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2 

  114. J. Biol. Chem Hsu 282 10432 2007 10.1074/jbc.M610014200 Characterization of a novel tripartite nuclear localization sequence in the EGFR family 

  115. Biochem. Biophys. Res. Commun Wang 399 498 2010 10.1016/j.bbrc.2010.07.096 COPI-mediated retrograde trafficking from the Golgi to the ER regulates EGFR nuclear transport 

  116. J. Biol. Chem Wang 287 16869 2012 10.1074/jbc.M111.314799 Membrane-bound trafficking regulates nuclear transport of integral epidermal growth factor receptor (EGFR) and ErbB-2 

  117. J. Cell. Biochem Lo 98 1570 2006 10.1002/jcb.20876 Nuclear-cytoplasmic transport of EGFR involves receptor endocytosis, importin β1 and CRM1 

  118. Mol. Cell. Biol Eldredge 14 7527 1994 10.1128/MCB.14.11.7527 Activation of c-fos gene expression by a kinase-deficient epidermal growth factor receptor 

  119. Mol. Carcinog Hanada 45 10 2006 10.1002/mc.20147 Co-regulation of B-Myb expression by E2F1 and EGF receptor 

  120. Cancer Cell Lo 7 575 2005 10.1016/j.ccr.2005.05.007 Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway 

  121. Oncogene Li 28 3801 2009 10.1038/onc.2009.234 Nuclear EGFR contributes to acquired resistance to cetuximab 

  122. Gene Dev Massague 19 2783 2005 10.1101/gad.1350705 Smad transcription factors 

  123. Nat. Rev. Drug Discov Akhurst 11 790 2012 10.1038/nrd3810 Targeting the TGF[beta] signalling pathway in disease 

  124. Cell Res Hill 19 36 2009 10.1038/cr.2008.325 Nucleocytoplasmic shuttling of Smad proteins 

  125. Cell Mullen 147 565 2011 10.1016/j.cell.2011.08.050 Master transcription factors determine cell-type-specific responses to TGF-β signaling 

  126. FEBS Lett Warner 539 167 2003 10.1016/S0014-5793(03)00155-8 Identification of three novel Smad binding proteins involved in cell polarity 

  127. Biochem. Biophys. Res. Commun Ellis 310 1117 2003 10.1016/j.bbrc.2003.09.130 Interaction of Smads with collagen types I, III, and V 

  128. Blood Quere 117 5918 2011 10.1182/blood-2010-08-301879 Smad4 binds Hoxa9 in the cytoplasm and protects primitive hematopoietic cells against nuclear activation by Hoxa9 and leukemia transformation 

  129. FEBS Lett Zwijsen 546 133 2003 10.1016/S0014-5793(03)00566-0 New intracellular components of bone morphogenetic protein/Smad signaling cascades 

관련 콘텐츠

오픈액세스(OA) 유형

GREEN

저자가 공개 리포지터리에 출판본, post-print, 또는 pre-print를 셀프 아카이빙 하여 자유로운 이용이 가능한 논문

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로