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Structural mechanism of GPCR-arrestin interaction: recent breakthroughs

Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea, v.39 no.3, 2016년, pp.293 - 301  

Park, Ji Young ,  Lee, Su Youn ,  Kim, Hee Ryung ,  Seo, Min-Duk ,  Chung, Ka Young

Abstract AI-Helper 아이콘AI-Helper

G protein-coupled receptors (GPCRs) are a major membrane receptor family with important physiological and pathological functions. In the classical signaling pathway, ligand-activated GPCRs couple to G proteins, thereby inducing G protein-dependent signaling pathways and phosphorylation by G protein-...

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