$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Purple rice anthocyanin extract protects cardiac function in STZ-induced diabetes rat hearts by inhibiting cardiac hypertrophy and fibrosis

The Journal of nutritional biochemistry, v.31, 2016년, pp.98 - 105  

Chen, Y.F. ,  Shibu, M.A. ,  Fan, M.J. ,  Chen, M.C. ,  Viswanadha, V.P. ,  Lin, Y.L. ,  Lai, C.H. ,  Lin, K.H. ,  Ho, T.J. ,  Kuo, W.W. ,  Huang, C.Y.

Abstract AI-Helper 아이콘AI-Helper

Diabetes mellitus (DM) often causes chronic inflammation, hypertrophy, apoptosis and fibrosis in the heart and subsequently leads to myocardial remodeling, deteriorated cardiac function and heart failure. Anthocyanins are strong antioxidants that show effective cardioprotective properties. Our aim w...

주제어

참고문헌 (40)

  1. Diabetes Obes Metab Colagiuri 12 463 2010 10.1111/j.1463-1326.2009.01182.x Diabesity: therapeutic options 

  2. BioImpacts Akhtar 3 5 2013 The role of epidermal growth factor receptor in diabetes-induced cardiac dysfunction 

  3. Diabetes Rajesh 61 716 2012 10.2337/db11-0477 Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy 

  4. Circ Res Iismaa 92 1059 2003 10.1161/01.RES.0000075792.92001.D4 Dissecting cardiac hypertrophy and signaling pathways: evidence for an interaction between multifunctional g proteins and prostanoids 

  5. Cell Mol Life Sci Wang 69 3561 2012 10.1007/s00018-012-1126-y The function of miRNA in cardiac hypertrophy 

  6. J Biol Chem Mir 287 2666 2012 10.1074/jbc.M111.246173 Inhibition of signal transducer and activator of transcription 3 (STAT3) attenuates interleukin-6 (IL-6)-induced collagen synthesis and resultant hypertrophy in rat heart 

  7. Trends Pharmacol Sci Cutler 32 174 2011 10.1016/j.tips.2010.12.001 Cardiac electrical remodeling in health and disease 

  8. Biomedicine Huang 2 36 2012 10.1016/j.biomed.2011.12.004 Possible pathophysiology of heart failure in obesity: cardiac apoptosis 

  9. Biomedicine Chang 2013 10.1016/j.biomed.2013.05.001 Inhibitory effect of alpinate oxyphyllae fructus extracts on Ang II-induced cardiac pathological remodeling-related pathways in H9c2 cardiomyoblast cells 

  10. Diabetes Metab Res Rev Broderick 21 44 2005 10.1002/dmrr.479 Exercise training restores abnormal myocardial glucose utilization and cardiac function in diabetes 

  11. Environ Toxicol Liao 2015 10.1002/tox.22086 Deep sea minerals prolong life span of streptozotocin-induced diabetic rats by compensatory augmentation of the IGF-I-survival signaling and inhibition of apoptosis 

  12. J Funct Foods Chiang 11 482 2014 10.1016/j.jff.2014.08.003 Lipolysis-stimulating peptide-VHVV ameliorates high fat diet induced hepatocyte apoptosis and fibrosis 

  13. J Funct Foods Huang 12 389 2015 10.1016/j.jff.2014.11.027 Potato protein hydrolysate attenuates high fat diet-induced cardiac apoptosis through SIRT1/PGC-1a/Akt signalling 

  14. Biomedicine Liao 4 8 2014 10.7603/s40681-014-0008-z Personalized medicine in type 2 diabetes 

  15. Int J Cardiol Tsai 195 300 2015 10.1016/j.ijcard.2015.05.111 Diallyl trisulfide protects against high glucose-induced cardiac apoptosis by stimulating the production of cystathionine gamma-lyase-derived hydrogen sulfide 

  16. Biomedicine Jao 5 14 2015 10.7603/s40681-015-0014-9 The development of bioactive peptides from dietary proteins as a dipeptidyl peptidase IV inhibitor for the management of type 2 diabetes 

  17. Adv Nutr Wallace 2 1 2011 10.3945/an.110.000042 Anthocyanins in cardiovascular disease 

  18. J Med Food Sun 15 288 2012 10.1089/jmf.2011.1806 Cyanidin-3-glucoside-rich extract from Chinese bayberry fruit protects pancreatic beta cells and ameliorates hyperglycemia in streptozotocin-induced diabetic mice 

  19. J Agric Food Chem Jayaprakasam 53 28 2005 10.1021/jf049018+ Insulin secretion by bioactive anthocyanins and anthocyanidins present in fruits 

  20. J Nutr Toufektsian 138 747 2008 10.1093/jn/138.4.747 Chronic dietary intake of plant-derived anthocyanins protects the rat heart against ischemia-reperfusion injury 

  21. J Nutr Biochem Palfi 20 418 2009 10.1016/j.jnutbio.2008.04.009 Alcohol-free red wine inhibits isoproterenol-induced cardiac remodeling in rats by the regulation of Akt1 and protein kinase C alpha/beta II 

  22. Am J Clin Nutr Hooper 88 38 2008 10.1093/ajcn/88.1.38 Flavonoids, flavonoid-rich foods, and cardiovascular risk: a meta-analysis of randomized controlled trials 

  23. Nutr Cancer Fan 67 327 2015 10.1080/01635581.2015.990576 Anthocyanins from black rice (Oryza sativa L.) demonstrate antimetastatic properties by reducing MMPs and NF-kappaB expressions in human oral cancer CAL 27 cells 

  24. Front Biosci Lopes-Virella 8 s750 2003 10.2741/1141 The role of immune and inflammatory processes in the development of macrovascular disease in diabetes 

  25. J Am Coll Cardiol Shiomi 42 165 2003 10.1016/S0735-1097(03)00509-6 Streptozotocin-induced hyperglycemia exacerbates left ventricular remodeling and failure after experimental myocardial infarction 

  26. Braz J Med Biol Res De Angelis 35 1091 2002 10.1590/S0100-879X2002000900010 Cardiovascular control in experimental diabetes 

  27. Cell Biochem Funct Kuo 27 479 2009 10.1002/cbf.1601 Effects of insulin replacement on cardiac apoptotic and survival pathways in streptozotocin-induced diabetic rats 

  28. Cardiovasc Res Boyd 72 384 2006 10.1016/j.cardiores.2006.09.011 Toll-like receptor stimulation in cardiomyoctes decreases contractility and initiates an NF-kappaB dependent inflammatory response 

  29. Int J Endocrinol Fuentes-Antras 2014 847827 2014 10.1155/2014/847827 Activation of toll-like receptors and inflammasome complexes in the diabetic cardiomyopathy-associated inflammation 

  30. Arterioscler Thromb Vasc Biol Bishop-Bailey 26 956 2006 10.1161/01.ATV.0000219672.68024.bc COX-2 in cardiovascular disease 

  31. Cell Metab Breyer 2 149 2005 10.1016/j.cmet.2005.08.009 Getting to the heart of COX-2 inhibition 

  32. Am J Physiol Heart Circ Physiol Moss 293 H2248 2007 10.1152/ajpheart.00776.2007 IKKbeta inhibition attenuates myocardial injury and dysfunction following acute ischemia-reperfusion injury 

  33. Basic Res Cardiol Eghbali 87 Suppl. 2 183 1992 Cardiac fibroblasts: function, regulation of gene expression, and phenotypic modulation 

  34. J Mol Cell Cardiol Riches 47 391 2009 10.1016/j.yjmcc.2009.06.002 Chronic hypoxia inhibits MMP-2 activation and cellular invasion in human cardiac myofibroblasts 

  35. Eur J Cardiovasc Prev Rehabil Hansson 16 297 2009 10.1097/HJR.0b013e3283213108 Relations of serum MMP-9 and TIMP-1 levels to left ventricular measures and cardiovascular risk factors: a population-based study 

  36. Circulation Peterson 103 2303 2001 10.1161/01.CIR.103.18.2303 Matrix metalloproteinase inhibition attenuates left ventricular remodeling and dysfunction in a rat model of progressive heart failure 

  37. Environ Toxicol Lai 2014 Lumbrokinase from earthworm extract ameliorates second-hand smoke-induced cardiac fibrosis 

  38. Thromb Haemost Lijnen 86 324 2001 10.1055/s-0037-1616230 Plasmin and matrix metalloproteinases in vascular remodeling 

  39. J Mol Cell Cardiol Gaertner 38 193 2005 10.1016/j.yjmcc.2004.10.017 The plasminogen-MMP system is more activated in the scar than in viable myocardium 3months post-MI in the rat 

  40. J Biol Chem Stempien-Otero 281 15345 2006 10.1074/jbc.M512818200 Mechanisms of cardiac fibrosis induced by urokinase plasminogen activator 

관련 콘텐츠

이 논문과 함께 이용한 콘텐츠

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로