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[해외논문] Insulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease 원문보기

Autophagy, v.12 no.5, 2016년, pp.784 - 800  

Son, Sung Min ,  Cha, Moon-Yong ,  Choi, Heesun ,  Kang, Seokjo ,  Choi, Hyunjung ,  Lee, Myung-Shik ,  Park, Sun Ah ,  Mook-Jung, Inhee

Abstract AI-Helper 아이콘AI-Helper

The secretion of proteins that lack a signal sequence to the extracellular milieu is regulated by their transition through the unconventional secretory pathway. IDE (insulin-degrading enzyme) is one of the major proteases of amyloid beta peptide (A beta), a presumed causative molecule in Alzheimer d...

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