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Chemical inhibition of autophagy: Examining its potential to increase the specific productivity of recombinant CHO cell lines

Biotechnology and bioengineering, v.113 no.9, 2016년, pp.1953 - 1961  

Baek, Eric (Department of Biological Sciences, KAIST, 335 Gwahak‐) ,  Kim, Che Lin (ro, Yuseong‐) ,  Kim, Mi Gyeom (gu, Daejeon 305‐) ,  Lee, Jae Seong (701, Republic of Korea) ,  Lee, Gyun Min (Department of Biological Sciences, KAIST, 335 Gwahak‐)

Abstract AI-Helper 아이콘AI-Helper

Chinese hamster ovary (CHO) cells activate and undergo apoptosis and autophagy for various environmental stresses. Unlike apoptosis, studies on increasing the production of therapeutic proteins in CHO cells by targeting the autophagy pathway are limited. In order to identify the effects of chemical ...

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참고문헌 (34)

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