[논문]Effects of Extended Freezer Storage on the Integrity of Human Milk

Ahrabi, A.F.; Handa, D.; Codipilly, C.N.; Shah, S.; Williams, J.E.; McGuire, M.A.; Potak, D.; Aharon, G.G.; Schanler, R.J.

doi:10.1016/j.jpeds.2016.06.024

Effects of Extended Freezer Storage on the Integrity of Human Milk

The Journal of pediatrics, v.177, 2016년, pp.140 - 143

Ahrabi, A.F. , Handa, D. , Codipilly, C.N. , Shah, S. , Williams, J.E. , McGuire, M.A. , Potak, D. , Aharon, G.G. , Schanler, R.J.

Abstract ▼ AI-Helper

Objective: To examine the integrity (pH, bacterial counts, host defense factors, nutrient contents, and osmolality) of freshly expressed and previously refrigerated human milk subjected to long-term freezer storage. Study design: Mothers donated 100@?mL of freshly expressed milk. Samples were divided into baseline, storage at -20oC (fresh frozen) for 1, 3, 6, and 9 months, and prior storage at +4oC for 72@?hours (refrigerated frozen) before storage at -20oC for 1 to 9 months. Samples were analyzed for pH, total bacterial colony count, gram-positive and gram-negative colony counts, and concentrations of total protein, fat, nonesterified fatty acids, lactoferrin, secretory IgA, and osmolality. Results: Milk pH, total bacterial colony count, and Gram-positive colony counts decreased significantly with freezer storage (P@?<@?.001); bacterial counts decreased most rapidly in the refrigerated frozen group. The gram-negative colony count decreased significantly over time (P@?<@?.001). Nonesterified fatty acid concentrations increased significantly with time in storage (P@?<@?.001). Freezing for up to 9 months did not affect total protein, fat, lactoferrin, secretory IgA, or osmolality in either group. Conclusions: Freezer storage of human milk for 9 months at -20oC is associated with decreasing pH and bacterial counts, but preservation of key macronutrients and immunoactive components, with or without prior refrigeration for 72@?hours. These data support current guidelines for freezer storage of human milk for up to 9 months for both freshly expressed and refrigerated milk.

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참고문헌 (20)

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Effects of Extended Freezer Storage on the Integrity of Human Milk

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