[논문]Calf raise exercise increases walking performance in patients with intermittent claudication

Van Schaardenburgh, M.; Wohlwend, M.; Rognmo, O.; Mattsson, E.

doi:10.1016/j.jvs.2016.12.106

Calf raise exercise increases walking performance in patients with intermittent claudication 원문보기

Journal of vascular surgery, v.65 no.5, 2017년, pp.1473 - 1482

Van Schaardenburgh, M. , Wohlwend, M. , Rognmo, O. , Mattsson, E.

Abstract ▼ AI-Helper

Background: Symptoms of intermittent claudication (IC) are improved by exercise. The improvement might be secondary to increased blood perfusion or increased muscle mitochondrial capacity. Ischemia followed by reperfusion, also named preconditioning, is known to stimulate the mitochondria. We focused on a calf raise exercise inducing preconditioning in the calf muscle of patients with IC. We hypothesized that 8 weeks of this exercise would increase walking performance and mitochondrial capacity without a change in blood flow. Methods: Patients with IC were randomized to either a calf raise exercise group (n = 14) or a traditional walking exercise group (n = 15). The calf raise group was instructed to perform a specific type of calf raise exercise three times a day. The walking group was instructed to walk near the pain threshold at least 30 minutes three times a week. Both interventions lasted 8 weeks and were not supervised. Measurements of walking performance, mitochondrial capacity, peak oxygen uptake, peripheral hemodynamics, and health-related quality of life were obtained on each patient before and after the intervention period. Adherence was measured by a training diary, and an activity monitor was used. Results: The calf raise group improved pain-free walking distance by 44 meters (P = .04) and maximal walking distance by 99 meters (P = .047). Furthermore, claudication onset time increased by 123 seconds (P = .02), and peak walking time increased by 104 seconds (P = .01). The calf raise group increased the enzyme citrate synthase activity, which is a biomarker of mitochondrial volume-density in the muscle tissue (P = .02). The walking group did not increase any of these variables. Maximal blood flow, peak oxygen uptake, and mitochondrial respiration did not change in any group. The calf raise group experienced less disease anxiety (P < .01). Adherence to the instruction of exercise was 100% in the calf raise group and 80% in the walking group. The calf raise group maintained physical activity. A reduction in activity (P < .01) was found in the walking group. Conclusions: Calf raise exercise improves walking performance and increases mitochondrial volume-density in the gastrocnemius muscle without increasing blood flow in patients with IC.

참고문헌 (38)

Eur J Vasc Endovasc Surg Norgren 33 Suppl 1 S1 2007 10.1016/j.ejvs.2006.09.024 Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II)

상세보기
J Vasc Surg Sigvant 45 1185 2007 10.1016/j.jvs.2007.02.004 A population-based study of peripheral arterial disease prevalence with special focus on critical limb ischemia and sex differences

상세보기
Lancet Fowkes 382 1329 2013 10.1016/S0140-6736(13)61249-0 Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysis

상세보기
Cochrane Database Syst Rev Fokkenrood CD005263 2013 Supervised exercise therapy versus non-supervised exercise therapy for intermittent claudication
Circulation Gardner 123 491 2011 10.1161/CIRCULATIONAHA.110.963066 Efficacy of quantified home-based exercise and supervised exercise in patients with intermittent claudication: a randomized controlled trial

상세보기
Vasc Med Mays 20 339 2015 10.1177/1358863X15572725 Community-based walking exercise for peripheral artery disease: an exploratory pilot study

상세보기
Am J Physiol Heart Circ Physiol Brass 280 H603 2001 10.1152/ajpheart.2001.280.2.H603 Decreased NADH dehydrogenase and ubiquinol-cytochrome c oxidoreductase in peripheral arterial disease

상세보기
J Vasc Surg Pipinos 38 827 2003 10.1016/S0741-5214(03)00602-5 Abnormal mitochondrial respiration in skeletal muscle in patients with peripheral arterial disease

상세보기
Free Rad Biol Med Pipinos 41 262 2006 10.1016/j.freeradbiomed.2006.04.003 Mitochondrial defects and oxidative damage in patients with peripheral arterial disease

상세보기
Clin Sci Lundgren 77 485 1989 10.1042/cs0770485 Muscle enzyme adaptation in patients with peripheral arterial insufficiency: spontaneous adaptation, effect of different treatments and consequences on walking performance

상세보기
Scand J Clin Lab Invest Suppl Holm 128 201 1973 Enzyme studies in muscles of patients with intermittent claudication. Effect of training

상세보기
JAMA Gardner 274 975 1995 10.1001/jama.1995.03530120067043 Exercise rehabilitation programs for the treatment of claudication pain. A meta-analysis

상세보기
J Vasc Surg Thaveau 46 541 2007 10.1016/j.jvs.2007.04.075 Ischemic preconditioning specifically restores complexes I and II activities of the mitochondrial respiratory chain in ischemic skeletal muscle

상세보기
Circ Res Slagsvold 114 851 2014 10.1161/CIRCRESAHA.114.302751 Remote ischemic preconditioning preserves mitochondrial function and influences myocardial microRNA expression in atrial myocardium during coronary bypass surgery

상세보기
Am J Respir Crit Care Med 166 111 2002 10.1164/ajrccm.166.1.at1102 ATS statement: guidelines for the six-minute walk test

상세보기
Circulation Hiatt 81 602 1990 10.1161/01.CIR.81.2.602 Benefit of exercise conditioning for patients with peripheral arterial disease

상세보기
J Am Geriatr Soc McDermott 46 1355 1998 10.1111/j.1532-5415.1998.tb06001.x The ankle brachial index independently predicts walking velocity and walking endurance in peripheral arterial disease

상세보기
Am J Physiol Heart Circ Physiol Alomari 286 H99 2004 10.1152/ajpheart.00529.2003 Measurements of vascular function using strain-gauge plethysmography: technical considerations, standardization, and physiological findings

상세보기
Eur Respir J Hayot 25 431 2005 10.1183/09031936.05.00053404 Skeletal muscle microbiopsy: a validation study of a minimally invasive technique

상세보기
PLoS One van Schaardenburgh 11 e0165038 2016 10.1371/journal.pone.0165038 Mitochondrial respiration after one session of calf raise exercise in patients with peripheral vascular disease and healthy older adults

상세보기
Methods Mol Biol Pesta 810 25 2012 10.1007/978-1-61779-382-0_3 High-resolution respirometry: OXPHOS protocols for human cells and permeabilized fibers from small biopsies of human muscle

상세보기
J Appl Physiol (1985) Jacobs 114 344 2013 10.1152/japplphysiol.01081.2012 Mitochondria express enhanced quality as well as quantity in association with aerobic fitness across recreationally active individuals up to elite athletes

상세보기
J Physiol Larsen 590 Pt 14 3349 2012 10.1113/jphysiol.2012.230185 Biomarkers of mitochondrial content in skeletal muscle of healthy young human subjects

상세보기
Diabetes Care Collins 34 2174 2011 10.2337/dc10-2399 Effects of a home-based walking intervention on mobility and quality of life in people with diabetes and peripheral arterial disease: a randomized controlled trial

상세보기
Eur J Vasc Endovasc Surg Mehta 31 46 2006 10.1016/j.ejvs.2005.08.028 Assessing the validity and responsiveness of disease-specific quality of life instruments in intermittent claudication

상세보기
J Cardiopulm Rehabil Lowensteyn 20 147 2000 10.1097/00008483-200005000-00002 The cost-effectiveness of exercise training for the primary and secondary prevention of cardiovascular disease

상세보기
Eur J Vasc Endovasc Surg Makris 44 569 2012 10.1016/j.ejvs.2012.09.009 Availability of supervised exercise programs and the role of structured home-based exercise in peripheral arterial disease

상세보기
Eur J Vasc Endovasc Surg van Asselt 41 97 2011 10.1016/j.ejvs.2010.06.024 Cost-effectiveness of exercise therapy in patients with intermittent claudication: supervised exercise therapy versus a “go home and walk” advice

상세보기
J Gerontol A Biol Sci Med Sci McGuigan 56 B302 2001 10.1093/gerona/56.7.B302 Resistance training in patients with peripheral arterial disease: effects on myosin isoforms, fiber type distribution, and capillary supply to skeletal muscle

상세보기
J Vasc Surg Ritti-Dias 51 89 2010 10.1016/j.jvs.2009.07.118 Strength training increases walking tolerance in intermittent claudication patients: randomized trial

상세보기
Eur J Appl Physiol Wang 104 749 2008 10.1007/s00421-008-0826-3 Plantar flexion: an effective training for peripheral arterial disease

상세보기
Sports Med Parmenter 40 433 2010 10.2165/11531330-000000000-00000 The effect of exercise on haemodynamics in intermittent claudication: a systematic review of randomized controlled trials

상세보기
Eur J Clin Invest Bylund 6 425 1976 10.1111/j.1365-2362.1976.tb00538.x Enzyme activities in skeletal muscles from patients with peripheral arterial insufficiency

상세보기
Cell Metab Egan 17 162 2013 10.1016/j.cmet.2012.12.012 Exercise metabolism and the molecular regulation of skeletal muscle adaptation

상세보기
J Gerontol A Biol Sci Med Sci Coen 68 447 2013 10.1093/gerona/gls196 Skeletal muscle mitochondrial energetics are associated with maximal aerobic capacity and walking speed in older adults

상세보기
Clin J Am Soc Nephrol Balakrishnan 5 996 2010 10.2215/CJN.09141209 Resistance training increases muscle mitochondrial biogenesis in patients with chronic kidney disease

상세보기
Clin Physiol Funct Imaging Hou 22 226 2002 10.1046/j.1475-097X.2002.00423.x Skeletal muscle mitochondrial ATP production rate and walking performance in peripheral arterial disease

상세보기
Physiol Behav Phielix 94 252 2008 10.1016/j.physbeh.2008.01.020 Type 2 diabetes mellitus and skeletal muscle metabolic function

상세보기

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Calf raise exercise increases walking performance in patients with intermittent claudication 원문보기

Abstract ▼ AI-Helper

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