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Anti-Melanogenic Activities of Heracleum moellendorffii via ERK1/2-Mediated MITF Downregulation 원문보기

International journal of molecular sciences, v.17 no.11, 2016년, pp.1844 -   

Alam, Md Badrul ,  Seo, Bum-Ju ,  Zhao, Peijun ,  Lee, Sang-Han

Abstract AI-Helper 아이콘AI-Helper

In this study, the anti-melanogenic effects of Heracleum moellendorffii Hance extract (HmHe) and the mechanisms through which it inhibits melanogenesis in melan-a cells were investigated. Mushroom tyrosinase (TYR) activity and melanin content as well as cellular tyrosinase activity were measured in ...

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참고문헌 (40)

  1. 1. Miyamura Y.I. Coelho S.G. Wolber R. Miller S.A. Wakamatsu K. Zmudzka B.Z. Ito S. Smuda C. Passeron T. Choi W. Regulation of human skin pigmentation and responses to ultraviolet radiation Pigment Cell Res. 2007 20 2 13 10.1111/j.1600-0749.2006.00358.x 17250543 

  2. 2. Jimbow K. Park J.S. Kato F. Hirosaki K. Toyofuku K. Hua C. Yamashita T. Assembly, target-signaling and intracellular transport of tyrosinase gene family proteins in the initial stage of melanosome biogenesis Pigment Cell Res. 2000 13 222 229 10.1034/j.1600-0749.2000.130403.x 10952389 

  3. 3. Lin J.Y. Fisher D.E. Melanocyte biology and skin pigmentation Nature 2007 445 843 850 10.1038/nature05660 17314970 

  4. 4. Ito S. Wakamatsu K. Chemistry of mixed melanogenesis—Pivotal roles of dopaquinone Photochem. Photobiol. 2008 84 582 592 10.1111/j.1751-1097.2007.00238.x 18435614 

  5. 5. Dong Y. Cao J. Wang H. Zhang J. Zhu Z. Bai R. Hao H. He X. Fan R. Dong C. Nitric oxide enhances the sensitivity of alpaca melanocytes to respond to α-melanocyte-stimulating hormone by up-regulating melanocortin-1 receptor Biochem. Biophys. Res. Commun. 2010 396 849 853 10.1016/j.bbrc.2010.05.001 20451493 

  6. 6. Horikoshi T. Nakahara M. Kaminaga H. Sasaki M. Uchiwa H. Miyachi Y. Involvement of nitric oxide in UVB-induced pigmentation in guinea pig skin Pigment Cell Res. 2000 13 358 363 10.1034/j.1600-0749.2000.130509.x 11041213 

  7. 7. Weller R. Nitric oxide: A key mediator in cutaneous physiology Clin. Exp. Dermatol. 2003 28 511 514 10.1046/j.1365-2230.2003.01365.x 12950342 

  8. 8. García-Gavín J. González-Vilas D. Fernández-Redondo V. Toribio J. Pigmented contact dermatitis due to kojic acid. A paradoxical side effect of a skin lightener Contact Dermat. 2010 62 63 64 10.1111/j.1600-0536.2009.01673.x 20136888 

  9. 9. Cheng S.L. Liu R.H. Sheu J.N. Chen S.T. Sinchaikul S. Tsay G.J. Toxicogenomics of A375 human malignant melanoma cells treated with arbutin J. Biomed. Sci. 2007 14 87 105 10.1007/s11373-006-9130-6 17103032 

  10. 10. Bang J.E. Choi H.Y. Kim S.I. Anti-oxidative activity and chemical composition of various Heracleum moellendorffii Hance extracts Korean J. Food Preserv. 2009 16 765 771 

  11. 11. Park H.J. Nugroho A. Jung B. Won Y.H. Jung Y.J. Kim W.B. Choi J.S. Isolation and quantitative analysis of flavonoids with peroxynitrite-scavenging effect from the young leaves of Heracleum moellendorffii Korean J. Plant Res. 2010 23 393 398 

  12. 12. Nakano Y. Matsunaga H. Saita T. Mori M. Katano M. Okabe H. Antiproliferative constituents in Umbelliferae plants II. Screening for polyacetylenes in some Umbelliferae plants, and isolation of panaxynol and falcarindiol from the root of Heracleum moellendorffii Biol. Pharm. Bull. 1998 21 257 261 10.1248/bpb.21.257 9556156 

  13. 13. Liu Z.L. Goh S.H. Ho S.H. Screening of Chinese medicinal herbs for bioactivity against Sitophilus zeamais Motschulsky and Tribolium castaneum (Herbst) J. Stored Prod. Res. 2007 43 290 296 10.1016/j.jspr.2006.06.010 

  14. 14. Chu S.S. Cao J. Liu Q.Z. Du S.S. Deng Z.W. Liu Z.L. Chemical composition and insecticidal activity of Heracleum moellendorffii Hance essential oil Chemija 2012 23 108 112 

  15. 15. Wu L.C. Chang L.H. Chen S.H. Fan N.C. Ho J.A. Antioxidant activity and melanogenesis inhibitory effect of the acetonic extract of Osmanthus fragrans : A potential natural and functional food flavor additive Food Sci. Technol. 2009 42 1513 1519 10.1016/j.lwt.2009.04.004 

  16. 16. Dewanto V. Wu X.Z. Adom K.K. Liu R.H. Thermal processing enhances the nutritional value of tomatoes by increasing total antioxidant activity J. Agric. Food Chem. 2002 50 3010 3014 10.1021/jf0115589 11982434 

  17. 17. Lee H.J. Lee W.J. Chang S.E. Lee G.Y. Hesperidin, a popular antioxidant inhibits melanogenesis via ERK1/2 mediated MITF degradation Int. J. Mol. Sci. 2015 16 18384 18395 10.3390/ijms160818384 26262610 

  18. 18. Hearing V.J. Determination of melanin synthetic pathways J. Investig. Dermatol. 2011 17 E8 E11 10.1038/skinbio.2011.4 22094404 

  19. 19. Jones K. Hughes J. Hong M. Jia Q. Orndorff S. Modulation of melanogenesis by aloesin: A competitive inhibitor of tyrosinase Pigment Cell Res. 2002 15 335 340 10.1034/j.1600-0749.2002.02014.x 12213089 

  20. 20. Chen J.S. Wei C.I. Marshall M.R. Inhibition mechanism of Kojic acid on polyphenol oxidase J. Agric. Food Chem. 1991 39 1897 1901 10.1021/jf00011a001 

  21. 21. Mastsuda M. Murata K. Fukuhama A. Naruto S. Fujita T. Uwaya A. Isami F. Matsuda H. Inhibitory effects of constituents of Morinda citrifolia seeds on elastase and tyrosinase J. Nat. Med. 2009 63 267 273 10.1007/s11418-009-0328-6 19308654 

  22. 22. Park S.H. Kim D.S. Lee H.K. Kwon S.B. Lee S. Ryoo I.J. Kim W.G. Yoo I.D. Park K.C. Long-term suppression of tyrosinase by terrein via tyrosinase degradation and its decreased expression Exp. Dermatol. 2009 18 562 566 10.1111/j.1600-0625.2009.00847.x 19493001 

  23. 23. Lin C.B. Babiarz L. Liebel F. Roydon-Price E. Kizoulis M. Gendimenico G.J. Fisher D.E. Seiberg M. Modulation of microphthalmia-associated transcription factor gene expression alters skin pigmentation J. Investig. Dermatol. 2002 119 1330 1340 10.1046/j.1523-1747.2002.19615.x 12485436 

  24. 24. Englaro W. Bertolotto C. Busca R. Brunet A. Pages G. Ortonne J.P. Ballotti R. Inhibition of the mitogen-activated protein kinase pathway triggers B16 melanoma cell differentiation J. Biol. Chem. 1998 273 9966 9970 10.1074/jbc.273.16.9966 9545341 

  25. 25. Kim D.S. Hwang E.S. Lee J.E. Kim S.Y. Kwon S.B. Park K.C. Sphingosine-1-phosphate decreases melanin synthesis via sustained ERK activation and subsequent MITF degradation J. Cell Sci. 2003 116 1699 1706 10.1242/jcs.00366 12665551 

  26. 26. Kim Y.J. Kang K.S. Yokozawa T. The anti-melanogenic effect of pycnogenol by its anti-oxidative actions Food Chem. Toxicol. 2008 46 2466 2471 10.1016/j.fct.2008.04.002 18482785 

  27. 27. Chu H.L. Wang B.S. Chang L.W. Wu H.C. Huang S.L. Huang M.H. Antioxidant and antityrosinase activity of aqueous extracts of green asparagus Food Chem. 2011 127 141 146 

  28. 28. Hanamura T. Uchida E. Aoki H. Skin-lightening effect of a polyphenol extract from acerola ( Malpighia emarginata DC.) fruit on UV-induced pigmentation Biosci. Biotechnol. Biochem. 2008 72 3211 3218 10.1271/bbb.80421 19060403 

  29. 29. Michihara A. Morita S. Hirokawa Y. Ago S. Akasaki K. Tsuji H. Deltatocotrienol causes decrease of melanin content in mouse melanoma cells J. Health Sci. 2009 55 314 318 10.1248/jhs.55.314 

  30. 30. Ohgidani M. Komizu Y. Goto K. Ueoka R. Antimelanogenic and antioxidative effects of residual powders from Shochu distillation remnants Food Chem. 2012 132 2140 2143 10.1016/j.foodchem.2011.12.049 

  31. 31. Baek S.H. Nam I.J. Kwak H.S. Kim K.C. Lee S.H. Cellular anti-melanogenic effects of a Euryale ferox seed extract ethyl acetate fraction via the lysosomal degradation machinery Int. J. Mol. Sci. 2015 16 9217 9235 10.3390/ijms16059217 25915032 

  32. 32. Ishihara Y. Oka M. Tsunakawa M. Tomita K. Hatori M. Yamamoto H. Kamei H. Miyaki T. Konishi M. Oki T. Melanostatin, a new melanin synthesis inhibitor. Production, isolation, chemical properties, structure and biological activity J. Antibiot. 1991 44 25 37 10.7164/antibiotics.44.25 1672125 

  33. 33. Bennett D.C. Cooper P.J. Hart I.R. A line of non-tumorigenic mouse melanocytes, syngeneic with the B16 melanoma and requiring a tumour promoter for growth Int. J. Cancer 1987 39 414 418 10.1002/ijc.2910390324 3102392 

  34. 34. Sato K. Takahashi H. Iraha R. Toriyama M. Down-regulation of tyrosinase expression by acetylsalicylic acid in murine B16 melanoma Biol. Pharm. Bull. 2008 31 33 37 10.1248/bpb.31.33 18175938 

  35. 35. Elias P.M. Menon G. Wetzel B.K. Williams J.W. Evidence that stress to the epidermal barrier influenced the development of pigmentation in humans Pigment Cell Melanoma Res. 2009 22 420 434 10.1111/j.1755-148X.2009.00588.x 19508412 

  36. 36. Rozen S. Skaletsky H. Primer3 on the WWW for general users and for biologist programmers Methods Mol. Biol. 2000 132 365 386 10547847 

  37. 37. Nanjo F. Goto K. Seto R. Suzuki M. Sakai M. Hara Y. Scavenging effects of tea catechins and their derivatives on 1,1-diphenyl-2-picrylhydrazyl radical Free Radic. Biol. Med. 1996 21 895 902 10.1016/0891-5849(96)00237-7 8902534 

  38. 38. Noguchi N. Yamashita H. Gotoh N. Yamamoto Y. Numano R. 2,2′-Azobis (4-Methoxy-2,4-Dimethylvaleronitrile), a new lipid-soluble azo initiator: Application to oxidations of lipids and low-density lipoprotein in solution and in aqueous dispersions Free Radic. Biol. Med. 1998 24 259 268 10.1016/S0891-5849(97)00230-X 9433901 

  39. 39. Apak R. Guclu K. Ozyurek M. Karademir S.E. Novel total antioxidant capacity index for dietary polyphenols and vitamins C and E, using their cupric ion reducing capability in the presence of neocuproine: CUPRAC method J. Agric. Food Chem. 2004 52 7970 7981 10.1021/jf048741x 15612784 

  40. 40. Ou B. Huang D. Hampsch-Woodill M. Flanagan J.A. Deemer E.K. Analysis of antioxidant activities of common vegetables employing oxygen radical absorbance capacity (ORAC) and ferric reducing antioxidant power (FRAP) assays: A comparative study J. Agric. Food Chem. 2002 50 3122 3128 10.1021/jf0116606 12009973 

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