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NTIS 바로가기BMC genomics, v.17, 2016년, pp.908 -
Jeong, Geon (Department of Biochemistry, Chonnam National University Medical School, Gwangju, Korea) , Lim, Yeong-Hwan (Department of Biochemistry, Chonnam National University Medical School, Gwangju, Korea) , Kim, Young-Kook (Department of Biochemistry, Chonnam National University Medical School, Gwangju, Korea)
BackgroundThe expression of microRNAs (miRNAs) is primarily regulated during their transcription. However, the transcriptional regulation of miRNA genes has not been studied extensively owing to the lack of sufficient information about the promoters and transcription start sites of most miRNAs.Resul...
1. Ha M Kim VN Regulation of microRNA biogenesis Nat Rev Mol Cell Biol 2014 15 509 524 10.1038/nrm3838 25027649
2. Kim YK Extracellular microRNAs as biomarkers in human disease Chonnam Med J 2015 51 51 57 10.4068/cmj.2015.51.2.51 26306299
3. Esteller M Non-coding RNAs in human disease Nat Rev Genet 2011 12 861 874 10.1038/nrg3074 22094949
4. Kim YK Kim VN Processing of intronic microRNAs EMBO J 2007 26 775 783 10.1038/sj.emboj.7601512 17255951
5. Rodriguez A Griffiths-Jones S Ashurst JL Bradley A Identification of mammalian microRNA host genes and transcription units Genome Res 2004 14 1902 1910 10.1101/gr.2722704 15364901
6. Morlando M Ballarino M Gromak N Pagano F Bozzoni I Proudfoot NJ Primary microRNA transcripts are processed co-transcriptionally Nat Struct Mol Biol 2008 15 902 909 10.1038/nsmb.1475 19172742
7. Kataoka N Fujita M Ohno M Functional association of the Microprocessor complex with the spliceosome Mol Cell Biol 2009 29 3243 3254 10.1128/MCB.00360-09 19349299
8. Agranat-Tamir L Shomron N Sperling J Sperling R Interplay between pre-mRNA splicing and microRNA biogenesis within the supraspliceosome Nucleic Acids Res 2014 42 4640 4651 10.1093/nar/gkt1413 24464992
9. Marsico A Huska MR Lasserre J Hu H Vucicevic D Musahl A Orom U Vingron M PROmiRNA: a new miRNA promoter recognition method uncovers the complex regulation of intronic miRNAs Genome Biol 2013 14 R84 10.1186/gb-2013-14-8-r84 23958307
10. Ozsolak F Poling LL Wang Z Liu H Liu XS Roeder RG Zhang X Song JS Fisher DE Chromatin structure analyses identify miRNA promoters Genes Dev 2008 22 3172 3183 10.1101/gad.1706508 19056895
11. Saini HK Enright AJ Griffiths-Jones S Annotation of mammalian primary microRNAs BMC Genomics 2008 9 564 10.1186/1471-2164-9-564 19038026
12. Corcoran DL Pandit KV Gordon B Bhattacharjee A Kaminski N Benos PV Features of mammalian microRNA promoters emerge from polymerase II chromatin immunoprecipitation data PLoS One 2009 4 10.1371/journal.pone.0005279 19390574
13. Chien CH Sun YM Chang WC Chiang-Hsieh PY Lee TY Tsai WC Horng JT Tsou AP Huang HD Identifying transcriptional start sites of human microRNAs based on high-throughput sequencing data Nucleic Acids Res 2011 39 9345 9356 10.1093/nar/gkr604 21821656
14. Marson A Levine SS Cole MF Frampton GM Brambrink T Johnstone S Guenther MG Johnston WK Wernig M Newman J Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells Cell 2008 134 521 533 10.1016/j.cell.2008.07.020 18692474
15. Georgakilas G Vlachos IS Paraskevopoulou MD Yang P Zhang Y Economides AN Hatzigeorgiou AG microTSS: accurate microRNA transcription start site identification reveals a significant number of divergent pri-miRNAs Nat Commun 2014 5 5700 10.1038/ncomms6700 25492647
16. Chang TC Pertea M Lee S Salzberg SL Mendell JT Genome-wide annotation of microRNA primary transcript structures reveals novel regulatory mechanisms Genome Res 2015 25 1401 1409 10.1101/gr.193607.115 26290535
17. Nepal C Coolen M Hadzhiev Y Cussigh D Mydel P Steen VM Carninci P Andersen JB Bally-Cuif L Muller F Lenhard B Transcriptional, post-transcriptional and chromatin-associated regulation of pri-miRNAs, pre-miRNAs and moRNAs Nucleic Acids Res 2016 44 3070 3081 10.1093/nar/gkv1354 26673698
18. Kim YK Kim B Kim VN Re-evaluation of the roles of DROSHA, Export in 5, and DICER in microRNA biogenesis Proc Natl Acad Sci U S A 2016 113 E1881 1889 10.1073/pnas.1602532113 26976605
19. Lee Y Kim M Han J Yeom KH Lee S Baek SH Kim VN MicroRNA genes are transcribed by RNA polymerase II EMBO J 2004 23 4051 4060 10.1038/sj.emboj.7600385 15372072
20. Kim YK Wee G Park J Kim J Baek D Kim JS Kim VN TALEN-based knockout library for human microRNAs Nat Struct Mol Biol 2013 20 1458 1464 10.1038/nsmb.2701 24213537
21. Consortium EP An integrated encyclopedia of DNA elements in the human genome Nature 2012 489 57 74 10.1038/nature11247 22955616
22. Cooper SJ Trinklein ND Anton ED Nguyen L Myers RM Comprehensive analysis of transcriptional promoter structure and function in 1 % of the human genome Genome Res 2006 16 1 10 10.1101/gr.4222606 16344566
23. Tabach Y Brosh R Buganim Y Reiner A Zuk O Yitzhaky A Koudritsky M Rotter V Domany E Wide-scale analysis of human functional transcription factor binding reveals a strong bias towards the transcription start site PLoS One 2007 2 10.1371/journal.pone.0000807 17726537
24. Koudritsky M Domany E Positional distribution of human transcription factor binding sites Nucleic Acids Res 2008 36 6795 6805 10.1093/nar/gkn752 18953043
25. Whitfield TW Wang J Collins PJ Partridge EC Aldred SF Trinklein ND Myers RM Weng Z Functional analysis of transcription factor binding sites in human promoters Genome Biol 2012 13 R50 10.1186/gb-2012-13-9-r50 22951020
26. Kannan MB Solovieva V Blank V The small MAF transcription factors MAFF, MAFG and MAFK: current knowledge and perspectives Biochim Biophys Acta 1823 2012 1841 1846
27. Ach RA Wang H Curry B Measuring microRNAs: comparisons of microarray and quantitative PCR measurements, and of different total RNA prep methods BMC Biotechnol 2008 8 69 10.1186/1472-6750-8-69 18783629
28. Heo I Joo C Cho J Ha M Han J Kim VN Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA Mol Cell 2008 32 276 284 10.1016/j.molcel.2008.09.014 18951094
29. Langmead B Salzberg SL Fast gapped-read alignment with Bowtie 2 Nat Methods 2012 9 357 359 10.1038/nmeth.1923 22388286
30. Kent WJ Sugnet CW Furey TS Roskin KM Pringle TH Zahler AM Haussler D The human genome browser at UCSC Genome Res 2002 12 996 1006 10.1101/gr.229102.ArticlepublishedonlinebeforeprintinMay2002 12045153
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