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European journal of pharmacology, v.830, 2018년, pp.17 - 25
Zhang, Le-Le (State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau) , Feng, Zhe-Ling (State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau) , Su, Min-Xia (State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau) , Jiang, Xiao-Ming (State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau) , Chen, Xiuping (State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau) , Wang, Yitao (State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau) , Li, Ao (College of Pharmacy and Bioengineering, Chongqing University of Technology) , Lin, Li-Gen (State Key) , Lu, Jin-Jian
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Abstract Non-small cell lung cancer (NSCLC) is one of the most common forms and leading causes of cancer-related mortality worldwide, and discovery of new effective drugs still remains imperative to improve the survival rate. Nagilactone E (NLE) is a natural product isolated from Podocarpus nagi se...
J. Ethnopharmacol. Abdillahi 139 728 2012 10.1016/j.jep.2011.11.044 Mutagenicity, antimutagenicity and cytotoxicity evaluation of South African Podocarpus species
Clin. Cancer Res. Agarwal 15 3654 2009 10.1158/1078-0432.CCR-08-3293 Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer
Mol. Cell Allan 26 301 2007 10.1016/j.molcel.2007.03.019 Phosphorylation of caspase-9 by CDK1/cyclin B1 protects mitotic cells against apoptosis
Proc. Natl. Acad. Sci. USA Bean 104 20932 2007 10.1073/pnas.0710370104 MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
Lipids Health Dis. Berger 1 5 2002 10.1186/1476-511X-1-5 Epidermal anti-Inflammatory properties of 5, 11, 14 20: 3: effects on mouse ear edema, PGE 2 levels in cultured keratinocytes, and PPAR activation
Food Chem. Toxicol. Chen 50 3687 2012 10.1016/j.fct.2012.07.057 Incorporation of sciadonic acid into cellular phospholipids reduces pro-inflammatory mediators in murine macrophages through NF-κB and MAPK signaling pathways
Nucleic Acids Res. Crombez 37 4559 2009 10.1093/nar/gkp451 Targeting cyclin B1 through peptide-based delivery of siRNA prevents tumour growth
Nat. Cell Biol. Dimova 14 168 2012 10.1038/ncb2425 APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1
Bioorg. Med. Chem. Evans 7 1953 1999 10.1016/S0968-0896(99)00162-5 The synthesis and antibacterial activity of totarol derivatives. Part 1: modifications of ring-C and pro-drugs
Nature Falck 434 605 2005 10.1038/nature03442 Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage
Phytochem. Lett. Feng 21 260 2017 10.1016/j.phytol.2017.07.011 Anti-inflammatory abietane diterpenoids from the seeds of Podocarpus nagi
J. Nat. Prod. Feng 80 2110 2017 10.1021/acs.jnatprod.7b00347 Norditerpenoids and dinorditerpenoids from the seeds of Podocarpus nagi as cytotoxic agents and autophagy inducers
1999 Flora of China
Cardiovasc. Res. Gui 112 502 2016 10.1093/cvr/cvw183 A novel small molecule liver X receptor transcriptional regulator, nagilactone B, suppresses atherosclerosis in apoE-deficient mice
Cancer Res. Hassan 62 6414 2002 Cyclin B1 overexpression and resistance to radiotherapy in head and neck squamous cell carcinoma
Magn. Reson. Chem. Hayashi 14 86 1980 Carbon13 NMR studies of the biologically active norditerpenoid dilactones from Podocarpus plants
Chem. Lett. Hayashi 1 759 1972 10.1246/cl.1972.759 Structures of nagilactone E and F, and biological activity of nagilactones as plant growth regulator
N. Engl. J. Med. Herbst 359 1367 2008 10.1056/NEJMra0802714 Lung cancer
Cell Hunter 80 225 1995 10.1016/0092-8674(95)90405-0 Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling
N. Engl. J. Med. Janne 372 1689 2015 10.1056/NEJMoa1411817 AZD9291 in EGFR inhibitor-resistant non-small-cell lung cancer
BMC Cancer Kedinger 13 338 2013 10.1186/1471-2407-13-338 Sticky siRNAs targeting survivin and cyclin B1 exert an antitumoral effect on melanoma subcutaneous xenografts and lung metastases
Nat. Cell Biol. Kirkpatrick 8 700 2006 10.1038/ncb1436 Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology
Front. Oncol. Korpanty 4 204 2014 10.3389/fonc.2014.00204 Biomarkers that currently affect clinical practice in lung cancer: EGFR, ALK, MET, ROS-1, and KRAS
J. Nat. Prod. Kubo 55 1436 1992 10.1021/np50088a008 Antibacterial activity of totarol and its potentiation
Mol. Cell. Biol. Matthess 30 5726 2010 10.1128/MCB.00731-10 Cdk1/cyclin B1 controls Fas-mediated apoptosis by regulating caspase-8 activity
EMBO J. Mcgowan 12 75 1993 10.1002/j.1460-2075.1993.tb05633.x Human Wee1 kinase inhibits cell division by phosphorylating p34cdc2 exclusively on Tyr15
Thorax Pilkington 2015 10.1136/thoraxjnl-2014-205914 A systematic review of the clinical effectiveness of first-line chemotherapy for adult patients with locally advanced or metastatic non-small cell lung cancer
Lung Cancer Rajeswaran 59 1 2008 10.1016/j.lungcan.2007.07.012
Nat. Prod. Res. Reynolds 20 606 2006 10.1080/14786410500249315 Cytotoxic diterpenoids from Podocarpus madagascariensis from the Madagascar rainforest
Annu. Rev. Biochem. Sancar 73 39 2004 10.1146/annurev.biochem.73.011303.073723 Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints
Phytomedicine Shrestha 8 489 2001 10.1078/S0944-7113(04)70071-9 An antiproliferative norditerpene dilactone, Nagilactone C, from Podocarpus neriifolius
CA Cancer J. Clin. S. Siegel 66 7 2016 10.3322/caac.21332 Cancer statistics, 2016
Biochim. Biophys. Acta Smits 1519 1 2001 10.1016/S0167-4781(01)00204-4 Checking out the G2/M transition
Cancer Res. Soria 60 4000 2000 Overexpression of cyclin B1 in early-stage non-small cell lung cancer and its clinical implication
Cancer Sci. Suzuki 98 644 2007 10.1111/j.1349-7006.2007.00444.x Nuclear cyclin B1 in human breast carcinoma as a potent prognostic factor
Nat. Med. Thress 21 560 2015 10.1038/nm.3854 Acquired EGFR C797S mutation mediates resistance to AZD9291 in non-small cell lung cancer harboring EGFR T790M
Cancer Epidemiol. Biomark. Prev. Torre 25 16 2016 10.1158/1055-9965.EPI-15-0578 Global cancer incidence and mortality rates and trends-an update
Cancer Discov. Trusolino 6 1306 2016 10.1158/2159-8290.CD-16-1181 Oncogenic MET as an effective therapeutic target in non-small cell lung cancer resistant to EGFR inhibitors: the rise of the phoenix
Nat. Prod. Lett. Wang 10 59 1997 10.1080/10575639708043697 Three new cytotoxic norditerpenoid dilactones from Podocarpus purdieanus Hook
Dev. Cell Wang 29 217 2014 10.1016/j.devcel.2014.03.012 Cyclin B1/Cdk1 coordinates mitochondrial respiration for cell-cycle G2/M progression
Proc. Natl. Acad. Sci. USA Yao 107 15535 2010 10.1073/pnas.1009472107 TGF-β IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer
Oncogene Yuan 23 5843 2004 10.1038/sj.onc.1207757 Cyclin B1 depletion inhibits proliferation and induces apoptosis in human tumor cells
Nat. Chem. Biol. Zeng 8 383 2012 10.1038/nchembio.801 An APC/C inhibitor stabilizes cyclin B1 by prematurely terminating ubiquitination
Molecules Zheng 21 1282 2016 10.3390/molecules21101282 Novel diterpenoids from the twigs of Podocarpus nagi
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