$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

[해외논문] Gut Microbiota Modulation and Its Relationship with Obesity Using Prebiotic Fibers and Probiotics: A Review 원문보기

Frontiers in microbiology, v.8, 2017년, pp.563 -   

Dahiya, Dinesh K. (Advanced Milk Testing Research Laboratory, Post Graduate Institute of Veterinary Education and Research –) ,  Renuka (Rajasthan University of Veterinary and Animal Sciences at Bikaner Jaipur, India) ,  Puniya, Monica (Department of Biochemistry, Basic Medical Science, South Campus, Panjab University Chandigarh, India) ,  Shandilya, Umesh K. (Food Safety Management System Division, Food Safety and Standards Authority of India New Delhi, India) ,  Dhewa, Tejpal (Animal Biotechnology Division, National Bureau of Animal Genetic Resources Karnal, India) ,  Kumar, Nikhil (Department of Nutrition Biology, Central University of Haryana Mahendergarh, India) ,  Kumar, Sanjeev (Department of Life Sciences, Shri Venkateshwara University JP Nagar, India) ,  Puniya, Anil K. (Department of Life Science, Central Assam University Silchar, India) ,  Shukla, Pratyoosh (College of Dairy Scie)

Abstract AI-Helper 아이콘AI-Helper

In the present world scenario, obesity has almost attained the level of a pandemic and is progressing at a rapid rate. This disease is the mother of all other metabolic disorders, which apart from placing an added financial burden on the concerned patient also has a negative impact on his/her well-b...

Keyword

참고문헌 (140)

  1. Aagaard K. Ma J. Antony K. M. Ganu R. Petrosino J. Versalovic J. ( 2014 ). The placenta harbors a unique microbiome. Sci. Trans. Med. 6 237 ra265. 10.1126/scitranslmed.3008599 

  2. Alard J. Lehrter V. Rhimi M. Mangin I. Peucelle V. Abraham A. L. ( 2016 ). Beneficial metabolic effects of selected probiotics on diet-induced obesity and insulin resistance in mice are associated with improvement of dysbiotic gut microbiota. Environ. Microbiol. 18 1484 – 1497 . 10.1111/1462-2920.13181 26689997 

  3. An H. M. Park S. Y. Lee D. K. Kim J. R. Cha M. K. Lee S. W. ( 2011 ). Antiobesity and lipid-lowering effects of Bifidobacterium spp. in high fat diet-induced obese rats. Lipids Health Dis. 10 : 116 10.1186/1476-511X-10-116 

  4. Angin Y. Beauloye C. Horman S. Bertrand L. ( 2016 ). “Regulation of carbohydrate metabolism, lipid metabolism, and protein metabolism by AMPK,” in AMP-Activated Protein Kinase , ( Berlin : Springer ), 23 – 43 . 10.1007/978-3-319-43589-3_2 

  5. Armougom F. Henry M. Vialettes B. Raccah D. Raoult D. ( 2009 ). Monitoring bacterial community of human gut microbiota reveals an increase in Lactobacillus in obese patients and Methanogens in anorexic patients. PLoS ONE 4 : e7125 10.1371/journal.pone.0007125 

  6. Aron-Wisnewsky J. Gaborit B. Dutour A. Clement K. ( 2013 ). Gut microbiota and non-alcoholic fatty liver disease: new insights. Clin. Microbiol. Infect 19 338 – 348 . 10.1111/1469-0691.12140 23452163 

  7. Arora T. Singh S. Sharma R. K. ( 2013 ). Probiotics: interaction with gut microbiome and antiobesity potential. Nutrition 29 591 – 596 . 10.1016/j.nut.2012.07.017 23287068 

  8. Arumugam M. Raes J. Pelletier E. Le Paslier D. Yamada T. Mende D. R. ( 2011 ). Enterotypes of the human gut microbiome. Nature 473 174 – 180 . 10.1038/nature09944 21508958 

  9. Bäckhed F. Ding H. Wang T. Hooper L. V. Koh G. Y. Nagy A. ( 2004 ). The gut microbiota as an environmental factor that regulates fat storage. Proc. Natl. Acad. Sci. U.S.A. 101 15718 – 15723 . 10.1073/pnas.0407076101 15505215 

  10. Bäckhed F. Manchester J. K. Semenkovich C. F. Gordon J. I. ( 2007 ). Mechanisms underlying the resistance to diet-induced obesity in germ-free mice. Proc. Natl. Acad. Sci. U.S.A. 104 979 – 984 . 10.1073/pnas.0605374104 17210919 

  11. Balamurugan R. George G. Kabeerdoss J. Hepsiba J. Chandragunasekaran A. M. Ramakrishna B. S. ( 2010 ). Quantitative differences in intestinal Faecalibacterium prausnitzii in obese Indian children. Br. J. Nutr. 103 335 – 338 . 10.1017/S0007114509992182 19849869 

  12. Boulangé C. L. Neves A. L. Chilloux J. Nicholson J. K. Dumas M.-E. ( 2016 ). Impact of the gut microbiota on inflammation, obesity, and metabolic disease. Genome Med. 8 : 42 10.1186/s13073-016-0303-2 

  13. Brown A. J. Goldsworthy S. M. Barnes A. A. Eilert M. M. Tcheang L. Daniels D. ( 2003 ). The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. J. Biol. Chem. 278 11312 – 11319 . 10.1074/jbc.M211609200 12496283 

  14. Cani P. D. Amar J. Iglesias M. A. Poggi M. Knauf C. Bastelica D. ( 2007a ). Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes Metab. Res. Rev. 56 1761 – 1772 . 10.2337/db06-1491 

  15. Cani P. D. Bibiloni R. Knauf C. Waget A. Neyrinck A. M. Delzenne N. M. ( 2008 ). Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet–induced obesity and diabetes in mice. Diabetes Metab. Res. Rev. 57 1470 – 1481 . 10.2337/db07-1403 

  16. Cani P. D. Dewever C. Delzenne N. M. ( 2004 ). Inulin-type fructans modulate gastrointestinal peptides involved in appetite regulation (glucagon-like peptide-1 and ghrelin) in rats. Br. J. Nutr. 92 521 – 526 . 10.1079/BJN20041225 15469657 

  17. Cani P. D. Everard A. Duparc T. ( 2013 ). Gut microbiota, enteroendocrine functions and metabolism. Curr. Opin. Pharmacol. 13 935 – 940 . 10.1016/j.coph.2013.09.008 24075718 

  18. Cani P. D. Hoste S. Guiot Y. Delzenne N. M. ( 2007b ). Dietary non-digestible carbohydrates promote L-cell differentiation in the proximal colon of rats. Br. J. Nutr. 98 32 – 37 . 17367575 

  19. Cani P. D. Joly E. Horsmans Y. Delzenne N. ( 2006a ). Oligofructose promotes satiety in healthy human: a pilot study. Eur. J. Clin. Nutr. 60 567 – 572 . 16340949 

  20. Cani P. D. Knauf C. Iglesias M. A. Drucker D. J. Delzenne N. M. Burcelin R. ( 2006b ). Improvement of glucose tolerance and hepatic insulin sensitivity by oligofructose requires a functional glucagon-like peptide 1 receptor. Diabetes Metab. Res. Rev. 55 1484 – 1490 . 

  21. Cani P. D. Lecourt E. Dewulf E. M. Sohet F. M. Pachikian B. D. Naslain D. ( 2009a ). Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal. Am. J. Clin. Nutr. 90 1236 – 1243 . 10.3945/ajcn.2009.28095 19776140 

  22. Cani P. D. Neyrinck A. Fava F. Knauf C. Burcelin R. Tuohy K. ( 2007c ). Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia. Diabetologia 50 2374 – 2383 . 17823788 

  23. Cani P. D. Possemiers S. Van de Wiele T. Guiot Y. Everard A. Rottier O. ( 2009b ). Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability. Gut 58 1091 – 1103 . 10.1136/gut.2008.165886 19240062 

  24. Chiang J. Y. ( 2009 ). Bile acids: regulation of synthesis. J. Lipid Res. 50 1955 – 1966 . 10.1194/jlr.R900010-JLR200 19346330 

  25. Cho I. Yamanishi S. Cox L. Methé B. A. Zavadil J. Li K. ( 2012 ). Antibiotics in early life alter the murine colonic microbiome and adiposity. Nature 488 621 – 626 . 10.1038/nature11400 22914093 

  26. Clarke S. F. Murphy E. F. O’Sullivan O. Ross R. P. O’Toole P. W. Shanahan F. ( 2013 ). Targeting the microbiota to address diet-induced obesity: a time dependent challenge. PLoS ONE 8 : e65790 10.1371/journal.pone.0065790 

  27. Cotillard A. Kennedy S. P. Kong L. C. Prifti E. Pons N. Le Chatelier E. ( 2013 ). Dietary intervention impact on gut microbial gene richness. Nature 500 585 – 588 . 10.1038/nature12480 23985875 

  28. Cox L. M. Yamanishi S. Sohn J. Alekseyenko A. V. Leung J. M. Cho I. ( 2014 ). Altering the intestinal microbiota during a critical developmental window has lasting metabolic consequences. Cell 158 705 – 721 . 10.1016/j.cell.2014.05.052 25126780 

  29. da Silva S. T. dos Santos C. A. Bressan J. ( 2013 ). Intestinal microbiota; relevance to obesity and modulation by prebiotics and probiotics. Nutr. Hosp. 28 1039 – 1048 . 10.3305/nh.2013.28.4.6525 23889619 

  30. Dahiya D. K. Puniya A. K. ( 2015 ). Evaluation of survival, free radical scavenging and human enterocyte adherence potential of Lactobacilli with anti-obesity and anti-inflammatory CLA isomer-producing attributes. J. Food Process. Preserv. 36 2866 – 2877 . 10.1111/jfpp.12538 

  31. Dahiya D. K. Puniya A. K. ( 2017 ). Isolation, molecular characterization and screening of indigenous lactobacilli for their abilities to produce bioactive conjugated linoleic acid (CLA). J. Food Sci. Technol. 54 792 – 801 . 10.1007/s13197-017-2523-x 28298694 

  32. Dao M. C. Everard A. Aron-Wisnewsky J. Sokolovska N. Prifti E. Verger E. O. ( 2016 ). Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology. Gut 65 426 – 436 . 10.1136/gutjnl-2014-308778 26100928 

  33. Davis J. E. Gabler N. K. Walker-Daniels J. Spurlock M. E. ( 2008 ). Tlr-4 deficiency selectively protects against obesity induced by diets high in saturated fat. Obesity 16 1248 – 1255 . 10.1038/oby.2008.210 18421279 

  34. De Silva A. Bloom S. R. ( 2012 ). Gut hormones and appetite control: a focus on PYY and GLP-1 as therapeutic targets in obesity. Gut Liver 6 10 – 20 . 10.5009/gnl.2012.6.1.10 22375166 

  35. Dewulf E. M. Cani P. D. Claus S. P. Fuentes S. Puylaert P. G. Neyrinck A. M. ( 2012 ). Insight into the prebiotic concept: lessons from an exploratory, double blind intervention study with inulin-type fructans in obese women. Gut 62 1112 – 1121 . 10.1136/gutjnl-2012-303304 23135760 

  36. Dray C. Knauf C. Daviaud D. Waget A. Boucher J. Buléon M. ( 2008 ). Apelin stimulates glucose utilization in normal and obese insulin-resistant mice. Cell Metab. 8 437 – 445 . 10.1016/j.cmet.2008.10.003 19046574 

  37. Druart C. Neyrinck A. M. Dewulf E. M. De Backer F. C. Possemiers S. Van de Wiele T. ( 2013 ). Implication of fermentable carbohydrates targeting the gut microbiota on conjugated linoleic acid production in high-fat-fed mice. Br. J. Nutr. 110 998 – 1011 . 10.1017/S0007114513000123 23507010 

  38. Duncan S. H. Belenguer A. Holtrop G. Johnstone A. M. Flint H. J. Lobley G. E. ( 2007 ). Reduced dietary intake of carbohydrates by obese subjects results in decreased concentrations of butyrate and butyrate-producing bacteria in feces. Appl. Environ. Microbiol. 73 1073 – 1078 . 10.1128/AEM.02340-06 17189447 

  39. Duncan S. H. Louis P. Thomson J. M. Flint H. J. ( 2009 ). The role of pH in determining the species composition of the human colonic microbiota. Environ. Microbiol. 11 2112 – 2222 . 10.1111/j.1462-2920.2009.01931.x 19397676 

  40. Dutton S. Trayhurn P. ( 2008 ). Regulation of angiopoietin-like protein 4/fasting-induced adipose factor (Angptl4/FIAF) expression in mouse white adipose tissue and 3T3-L1 adipocytes. Br. J. Nutr. 100 18 – 26 . 10.1017/S0007114507882961 18081944 

  41. Eckburg P. B. Bik E. M. Bernstein C. N. Purdom E. Dethlefsen L. Sargent M. ( 2005 ). Diversity of the human intestinal microbial flora. Science 308 1635 – 1638 . 10.1126/science.1110591 15831718 

  42. Everard A. Belzer C. Geurts L. Ouwerkerk J. P. Druart C. Bindels L. B. ( 2013 ). Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity. Proc. Natl. Acad. Sci. U.S.A. 110 9066 – 9071 . 10.1073/pnas.1219451110 23671105 

  43. Everard A. Lazarevic V. Derrien M. Girard M. Muccioli G. G. Neyrinck A. M. ( 2011 ). Responses of gut microbiota and glucose and lipid metabolism to prebiotics in genetic obese and diet-induced leptin-resistant mice. Diabetes Metab. Res. Rev. 60 2775 – 2786 . 10.2337/db11-0227 

  44. Everard A. Lazarevic V. Gaïa N. Johansson M. Ståhlman M. Backhed F. ( 2014 ). Microbiome of prebiotic-treated mice reveals novel targets involved in host response during obesity. ISME J. 8 2116 – 2130 . 10.1038/ismej.2014.45 24694712 

  45. Feng J. Tang H. Li M. Pang X. Wang L. Zhang M. ( 2014 ). The abundance of fecal Faecalibacterium prausnitzii in relation to obesity and gender in Chinese adults. Arch. Microbiol. 196 73 – 77 . 10.1007/s00203-013-0942-2 24292154 

  46. Fleissner C. K. Huebel N. El-Bary M. M. A. Loh G. Klaus S. Blaut M. ( 2010 ). Absence of intestinal microbiota does not protect mice from diet-induced obesity. Br. J. Nutr. 104 919 – 929 . 10.1017/S0007114510001303 20441670 

  47. Franzosa E. A. Huang K. Meadow J. F. Gevers D. Lemon K. P. Bohannan B. J. ( 2015 ). Identifying personal microbiomes using metagenomic codes. Proc. Natl. Acad. Sci. U.S.A. 112 E2930 – E2938 . 10.1073/pnas.1423854112 25964341 

  48. Gad G. F. M. Abdel-Hamid A. M. Farag Z. S. H. ( 2014 ). Antibiotic resistance in lactic acid bacteria isolated from some pharmaceutical and dairy products. Braz. J. Microbiol. 45 25 – 33 . 10.1590/S1517-83822014000100005 24948910 

  49. Gérard P. ( 2016 ). Gut microbiota and obesity. Cell. Mol. Life Sci. 73 147 – 162 . 10.1007/s00018-015-2061-5 26459447 

  50. Geurts L. Lazarevic V. Derrien M. Everard A. Van Roye M. Knauf C. ( 2011 ). Altered gut microbiota and endocannabinoid system tone in obese and diabetic leptin-resistant mice: impact on apelin regulation in adipose tissue. Front. Microbiol. 2 : 149 10.3389/fmicb.2011.00149 

  51. Gibson G. R. Probert H. M. Van Loo J. Rastall R. A. Roberfroid M. B. ( 2004 ). Dietary modulation of the human colonic microbiota: updating the concept of prebiotics. Nutr. Res. Rev. 17 259 – 275 . 10.1079/NRR200479 19079930 

  52. Go G.-W. Oh S. Park M. Gang G. McLean D. Yang H.-S. ( 2013 ). t10, c12 conjugated linoleic acid upregulates hepatic de novo lipogenesis and triglyceride synthesis via mTOR pathway activation. J. Microbiol. Biotechnol. 23 1569 – 1576 . 10.4014/jmb.1308.08008 24018969 

  53. Hotamisligil G. S. ( 2006 ). Inflammation and metabolic disorders. Nature 444 860 – 867 . 10.1038/nature05485 17167474 

  54. Joossens M. Huys G. Van Steen K. Cnockaert M. Vermeire S. Rutgeerts P. ( 2011 ). High-throughput method for comparative analysis of denaturing gradient gel electrophoresis profiles from human fecal samples reveals significant increases in two bifidobacterial species after inulin-type prebiotic intake. FEMS Microbiol. Ecol. 75 343 – 349 . 10.1111/j.1574-6941.2010.01008.x 21133959 

  55. Karra E. Chandarana K. Batterham R. L. ( 2009 ). The role of peptide YY in appetite regulation and obesity. J. Physiol. 587 19 – 25 . 10.1113/jphysiol.2008.164269 19064614 

  56. Kasubuchi M. Hasegawa S. Hiramatsu T. Ichimura A. Kimura I. ( 2015 ). Dietary gut microbial metabolites, short-chain fatty acids, and host metabolic regulation. Nutrients 7 2839 – 2849 . 10.3390/nu7042839 25875123 

  57. Kim J. Yang G. Ha J. ( 2017 ). Targeting of AMP-activated protein kinase: prospects for computer-aided drug design. Expert Opin. Drug Dis. 12 47 – 59 . 10.1080/17460441.2017.1255194 

  58. Kim K.-A. Jeong J.-J. Kim D.-H. ( 2015 ). Lactobacillus brevis OK56 ameliorates high-fat diet-induced obesity in mice by inhibiting NF-κB activation and gut microbial LPS production. J. Funct. Foods 13 183 – 191 . 10.1016/j.jff.2014.12.045 

  59. Kimura I. Ozawa K. Inoue D. Imamura T. Kimura K. Maeda T. ( 2013 ). The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43. Nat. Commun. 4 1829 10.1038/ncomms2852 

  60. Knights D. Ward T. L. McKinlay C. E. Miller H. Gonzalez A. McDonald D. ( 2014 ). Rethinking “enterotypes”. Cell Host Microbe 16 433 – 437 . 10.1016/j.chom.2014.09.013 25299329 

  61. Koenig J. E. Spor A. Scalfone N. Fricker A. D. Stombaugh J. Knight R. ( 2011 ). Succession of microbial consortia in the developing infant gut microbiome. Proc. Natl. Acad. Sci. U.S.A. 108(Suppl. 1) , 4578 – 4585 . 10.1073/pnas.1000081107 20668239 

  62. Koh A. De Vadder F. Kovatcheva-Datchary P. Bäckhed F. ( 2016 ). From dietary fiber to host physiology: short-chain fatty acids as key bacterial metabolites. Cell 165 1332 – 1345 . 10.1016/j.cell.2016.05.041 27259147 

  63. Kopelman P. ( 2007 ). Health risks associated with overweight and obesity. Obes. Rev. 8 13 – 17 . 10.1111/j.1467-789X.2007.00311.x 17316295 

  64. Koren O. Knights D. Gonzalez A. Waldron L. Segata N. Knight R. ( 2013 ). A guide to enterotypes across the human body: meta-analysis of microbial community structures in human microbiome datasets. PLoS Comput. Biol. 9 : e1002863 10.1371/journal.pcbi.1002863 

  65. Larsen N. Vogensen F. K. Gøbel R. J. Michaelsen K. F. Forssten S. D. Lahtinen S. J. ( 2013 ). Effect of Lactobacillus salivarius Ls-33 on fecal microbiota in obese adolescents. Clin. Nutr. 32 935 – 940 . 10.1016/j.clnu.2013.02.007 23510724 

  66. Le Chatelier E. Nielsen T. Qin J. Prifti E. Hildebrand F. Falony G. ( 2013 ). Richness of human gut microbiome correlates with metabolic markers. Nature 500 541 – 546 . 10.1038/nature12506 23985870 

  67. Le Poul E. Loison C. Struyf S. Springael J.-Y. Lannoy V. Decobecq M.-E. ( 2003 ). Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation. J. Biol. Chem. 278 25481 – 25489 . 10.1074/jbc.M301403200 12711604 

  68. Lee S. J. Bose S. Seo J.-G. Chung W.-S. Lim C.-Y. Kim H. ( 2014 ). The effects of co-administration of probiotics with herbal medicine on obesity, metabolic endotoxemia and dysbiosis: a randomized double-blind controlled clinical trial. Clin. Nutr. 33 973 – 981 . 10.1016/j.clnu.2013.12.006 24411490 

  69. Letran S. E. Lee S.-J. Atif S. M. Flores-Langarica A. Uematsu S. Akira S. ( 2011 ). TLR5-deficient mice lack basal inflammatory and metabolic defects but exhibit impaired CD4 T cell responses to a flagellated pathogen. J. Immunol. 186 5406 – 5412 . 10.4049/jimmunol.1003576 21451112 

  70. Leung C. Rivera L. Furness J. B. Angus P. W. ( 2016 ). The role of the gut microbiota in NAFLD. Nat. Rev. Gastroenterol. Hepatol. 13 412 – 425 . 10.1038/nrgastro.2016.85 27273168 

  71. Ley R. E. Bäckhed F. Turnbaugh P. Lozupone C. A. Knight R. D. Gordon J. I. ( 2005 ). Obesity alters gut microbial ecology. Proc. Natl. Acad. Sci. U.S.A. 102 11070 – 11075 . 10.1073/pnas.0504978102 16033867 

  72. Ley R. E. Turnbaugh P. J. Klein S. Gordon J. I. ( 2006 ). Microbial ecology: human gut microbes associated with obesity. Nature 444 1022 – 1023 . 10.1038/4441022a 17183309 

  73. Lim S.-M. Jeong J.-J. Woo K. H. Han M. J. Kim D.-H. ( 2016 ). Lactobacillus sakei OK67 ameliorates high-fat diet–induced blood glucose intolerance and obesity in mice by inhibiting gut microbiota lipopolysaccharide production and inducing colon tight junction protein expression. Nutr. Res. 36 337 – 348 . 10.1016/j.nutres.2015.12.001 27001279 

  74. Louis P. Flint H. J. ( 2009 ). Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine. FEMS Microbiol. Lett. 294 1 – 8 . 10.1111/j.1574-6968.2009.01514.x 19222573 

  75. Luna R. A. Foster J. A. ( 2015 ). Gut brain axis: diet microbiota interactions and implications for modulation of anxiety and depression. Curr. Opin. Biotechnol. 32 35 – 41 . 10.1016/j.copbio.2014.10.007 25448230 

  76. Luoto R. Kalliomäki M. Laitinen K. Isolauri E. ( 2010 ). The impact of perinatal probiotic intervention on the development of overweight and obesity: follow-up study from birth to 10 years. Int. J. Obes. 34 1531 – 1537 . 10.1038/ijo.2010.50 

  77. Mackie K. ( 2008 ). Cannabinoid receptors: where they are and what they do. J. Neuroendocrinol. 20 10 – 14 . 10.1111/j.1365-2826.2008.01671.x 18426493 

  78. Maenhaut N. Van de Voorde J. ( 2011 ). Regulation of vascular tone by adipocytes. BMC Med. 9 : 25 10.1186/1741-7015-9-25 

  79. Marteau P. Seksik P. ( 2004 ). Tolerance of probiotics and prebiotics. J. Clin. Gastroenterol. 38 S67 – S69 . 10.1097/01.mcg.0000128929.37156.a7 15220662 

  80. Medzhitov R. ( 2001 ). Toll-like receptors and innate immunity. Nat. Rev. Immunol. 1 135 – 145 . 10.1038/35100529 11905821 

  81. Million M. Angelakis E. Paul M. Armougom F. Leibovici L. Raoult D. ( 2012a ). Comparative meta-analysis of the effect of Lactobacillus species on weight gain in humans and animals. Microb. Pathog. 53 100 – 108 . 10.1016/j.micpath.2012.05.007 22634320 

  82. Million M. Maraninchi M. Henry M. Armougom F. Richet H. Carrieri P. ( 2012b ). Obesity-associated gut microbiota is enriched in Lactobacillus reuteri and depleted in Bifidobacterium animalis and Methanobrevibacter smithii . Int. J. Obes. 36 817 – 825 . 10.1038/ijo.2011.153 

  83. Miquel S. Martín R. Rossi O. Bermúdez-Humarán L. G. Chatel J. M. Sokol H. ( 2013 ). Faecalibacterium prausnitzii and human intestinal health. Curr. Opin. Microbiol. 16 255 – 261 . 10.1016/j.mib.2013.06.003 23831042 

  84. Muccioli G. G. Naslain D. Bäckhed F. Reigstad C. S. Lambert D. M. Delzenne N. M. ( 2010 ). The endocannabinoid system links gut microbiota to adipogenesis. Mol. Syst. Biol. 6 392 10.1038/msb.2010.46 

  85. Mueller N. T. Whyatt R. Hoepner L. Oberfield S. Dominguez-Bello M. G. Widen E. ( 2014 ). Prenatal exposure to antibiotics, cesarean section and risk of childhood obesity. Int. J. Obes. 39 665 – 670 . 10.1038/ijo.2014.180 

  86. Murphy E. F. Cotter P. D. Hogan A. O’sullivan O. Joyce A. Fouhy F. ( 2013 ). Divergent metabolic outcomes arising from targeted manipulation of the gut microbiota in diet-induced obesity. Gut 62 220 – 226 . 10.1136/gutjnl-2011-300705 22345653 

  87. Neyrinck A. M. Possemiers S. Druart C. Van de Wiele T. De Backer F. Cani P. D. ( 2011 ). Prebiotic effects of wheat arabinoxylan related to the increase in bifidobacteria, Roseburia and Bacteroides / Prevotella in diet-induced obese mice. PLoS ONE 6 : e20944 10.1371/journal.pone.0020944 

  88. Nikolopoulou A. Kadoglou N. P. ( 2012 ). Obesity and metabolic syndrome as related to cardiovascular disease. Expert Rev. Cardiovasc. Ther. 10 933 – 939 . 10.1586/erc.12.74 22908926 

  89. Nøhr M. K. Pedersen M. H. Gille A. Egerod K. L. Engelstoft M. S. Husted A. S. ( 2013 ). GPR41/FFAR3 and GPR43/FFAR2 as cosensors for short-chain fatty acids in enteroendocrine cells vs FFAR3 in enteric neurons and FFAR2 in enteric leukocytes. Endocrinology 154 3552 – 3564 . 10.1210/en.2013-1142 23885020 

  90. Ouchi N. Parker J. L. Lugus J. J. Walsh K. ( 2011 ). Adipokines in inflammation and metabolic disease. Nat. Rev. Immunol. 11 85 – 97 . 10.1038/nri2921 21252989 

  91. Park D. Y. Ahn Y. T. Park S. H. Huh C. S. Yoo S. R. Yu R. ( 2013 ). Supplementation of Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032 in diet-induced obese mice is associated with gut microbial changes and reduction in obesity. PLoS ONE 8 : e59470 10.1371/journal.pone.0059470 

  92. Park S. Ji Y. Jung H.-Y. Park H. Kang J. Choi S.-H. ( 2017 ). Lactobacillus plantarum HAC01 regulates gut microbiota and adipose tissue accumulation in a diet-induced obesity murine model. Appl. Microbiol. Biotechnol. 101 1605 – 1614 . 10.1007/s00253-016-7953-2 27858139 

  93. Parnell J. A. Reimer R. A. ( 2009 ). Weight loss during oligofructose supplementation is associated with decreased ghrelin and increased peptide YY in overweight and obese adults. Am. J. Clin. Nutr. 89 1751 – 1759 . 10.3945/ajcn.2009.27465 19386741 

  94. Perez-Chanona E. Trinchieri G. ( 2016 ). The role of microbiota in cancer therapy. Curr. Opin. Immunol. 39 75 – 81 . 10.1016/j.coi.2016.01.003 26820225 

  95. Peterson C. Sharma V. Elmén L. Peterson S. ( 2015 ). Immune homeostasis, dysbiosis and therapeutic modulation of the gut microbiota. Clin. Exp. Immunol. 179 363 – 377 . 10.1111/cei.12474 25345825 

  96. Podolsky S. H. ( 2017 ). Historical perspective on the rise and fall and rise of antibiotics and human weight gainhistorical perspective on antibiotics and human weight gain. Ann. Intern. Med. 166 133 – 138 . 10.7326/M16-1855 28114473 

  97. Qin J. Li R. Raes J. Arumugam M. Burgdorf K. S. Manichanh C. ( 2010 ). A human gut microbial gene catalogue established by metagenomic sequencing. Nature 464 59 – 65 . 10.1038/nature08821 20203603 

  98. Quigley E. M. ( 2011 ). Gut microbiota and the role of probiotics in therapy. Curr. Opin. Pharmacol. 11 593 – 603 . 10.1016/j.coph.2011.09.010 21996283 

  99. Rajkumar H. Kumar M. Das N. Kumar S. N. Challa H. R. Nagpal R. ( 2015 ). Effect of probiotic Lactobacillus salivarius UBL S22 and prebiotic fructo-oligosaccharide on serum lipids, inflammatory markers, insulin sensitivity, and gut bacteria in healthy young volunteers: a randomized controlled single-blind pilot study. J. Cardiovasc. Pharmacol. Ther. 20 289 – 298 . 10.1177/1074248414555004 25331262 

  100. Ramirez-Farias C. Slezak K. Fuller Z. Duncan A. Holtrop G. Louis P. ( 2009 ). Effect of inulin on the human gut microbiota: stimulation of Bifidobacterium adolescentis and Faecalibacterium prausnitzii . Br. J. Nutr. 101 541 – 550 . 10.1017/S0007114508019880 18590586 

  101. Rather S. A. Pothuraju R. Sharma R. K. De S. Mir N. A. Jangra S. ( 2014 ). Anti-obesity effect of feeding probiotic dahi containing Lactobacillus casei NCDC 19 in high fat diet-induced obese mice. Int. J. Dairy Technol. 67 504 – 509 . 10.1111/1471-0307.12154 

  102. Regard J. B. Sato I. T. Coughlin S. R. ( 2008 ). Anatomical profiling of G protein-coupled receptor expression. Cell 135 561 – 571 . 10.1016/j.cell.2008.08.040 18984166 

  103. Remely M. Hippe B. Zanner J. Aumueller E. Brath H. Haslberger A. G. ( 2016 ). Gut microbiota of obese, type 2 diabetic individuals is enriched in Faecalibacterium prausnitzii , Akkermansia muciniphila and Peptostreptococcus anaerobius after weight loss. Endocr. Metab. Immune Disord. Drug Targets 16 99 – 106 . 10.2174/1871530316666160831093813 

  104. Respondek F. Gerard P. Bossis M. Boschat L. Bruneau A. Rabot S. ( 2013 ). Short-chain fructo-oligosaccharides modulate intestinal microbiota and metabolic parameters of humanized gnotobiotic diet induced obesity mice. PLoS ONE 8 : e71026 10.1371/journal.pone.0071026 

  105. Ridlon J. M. Kang D. J. Hylemon P. B. Bajaj J. S. ( 2014 ). Bile acids and the gut microbiome. Curr. Opin. Gastroenterol. 30 332 – 338 . 10.1097/MOG.0000000000000057 24625896 

  106. Riva A. Borgo F. Lassandro C. Verduci E. Morace G. Borghi E. ( 2017 ). Pediatric obesity is associated with an altered gut microbiota and discordant shifts in Firmicutes populations. Environ. Microbiol. 19 95 – 105 . 10.1111/1462-2920.13463 27450202 

  107. Rosenbaum M. Knight R. Leibel R. L. ( 2015 ). The gut microbiota in human energy homeostasis and obesity. Trends Endocrinol. Metab. 26 493 – 501 . 10.1016/j.tem.2015.07.002 26257300 

  108. Salazar N. Dewulf E. M. Neyrinck A. M. Bindels L. B. Cani P. D. Mahillon J. ( 2015 ). Inulin-type fructans modulate intestinal Bifidobacterium species populations and decrease fecal short-chain fatty acids in obese women. Clin. Nutr. 34 501 – 507 . 10.1016/j.clnu.2014.06.001 24969566 

  109. Sanders M. E. ( 2008 ). Probiotics: definition, sources, selection, and uses. Clin. Infect. Dis. 46(Suppl. 2) , S58 – S61 . 10.1086/523341 18181724 

  110. Sanz Y. Rastmanesh R. Agostonic C. ( 2013 ). Understanding the role of gut microbes and probiotics in obesity: how far are we? Pharmacol. Res. 69 144 – 155 . 10.1016/j.phrs.2012.10.021 23147032 

  111. Sayin S. I. Wahlström A. Felin J. Jäntti S. Marschall H.-U. Bamberg K. ( 2013 ). Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist. Cell Metab. 17 225 – 235 . 10.1016/j.cmet.2013.01.003 23395169 

  112. Schneeberger M. Everard A. Gómez-Valadés A. G. Matamoros S. Ramírez S. Delzenne N. M. ( 2015 ). Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice. Sci. Rep. 5 : 16643 10.1038/srep16643 

  113. Singh S. Sharma R. Malhotra S. Pothuraju R. Shandilya U. ( 2016 ). Lactobacillus rhamnosus NCDC17 ameliorates type-2 diabetes by improving gut function, oxidative stress and inflammation in high-fat-diet fed and streptozotocintreated rats. Benef. Microbes 10.3920/BM2016.0090 [Epub ahead of print] . 

  114. Sommer F. Bäckhed F. ( 2013 ). The gut microbiota—masters of host development and physiology. Nat. Rev. Microbiol. 11 227 – 238 . 10.1038/nrmicro2974 23435359 

  115. Stanton C. Ross R. P. Fitzgerald G. F. Van Sinderen D. ( 2005 ). Fermented functional foods based on probiotics and their biogenic metabolites. Curr. Opin. Biotechnol. 16 198 – 203 . 10.1038/nrmicro2974 15831387 

  116. Steinert R. Beglinger C. Langhans W. ( 2016 ). Intestinal GLP-1 and satiation: from man to rodents and back. Int. J. Obes. 40 198 – 205 . 10.1038/ijo.2015.172 

  117. Swann J. R. Want E. J. Geier F. M. Spagou K. Wilson I. D. Sidaway J. E. ( 2011 ). Systemic gut microbial modulation of bile acid metabolism in host tissue compartments. Proc. Natl. Acad. Sci. U.S.A. 108(Suppl. 1) , 4523 – 4530 . 10.1073/pnas.1006734107 20837534 

  118. Swinburn B. A. Sacks G. Hall K. D. McPherson K. Finegood D. T. Moodie M. L. ( 2011 ). The global obesity pandemic: shaped by global drivers and local environments. Lancet 378 804 – 814 . 10.1016/S0140-6736(11)60813-1 21872749 

  119. Tarini J. Wolever T. M. ( 2010 ). The fermentable fibre inulin increases postprandial serum short-chain fatty acids and reduces free-fatty acids and ghrelin in healthy subjects. Appl. Physiol. Nutr. Metab. 35 9 – 16 . 10.1139/H09-119 20130660 

  120. Tolhurst G. Heffron H. Lam Y. S. Parker H. E. Habib A. M. Diakogiannaki E. ( 2012 ). Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein–coupled receptor FFAR2. Diabetes Metab. Res. Rev. 61 364 – 371 . 10.2337/db11-1019 

  121. Toral M. Gómez-Guzmán M. Jiménez R. Romero M. Sánchez M. Utrilla M. P. ( 2014 ). The probiotic Lactobacillus coryniformis CECT5711 reduces the vascular pro-oxidant and pro-inflammatory status in obese mice. Clin. Sci. 127 33 – 45 . 10.1042/CS20130339 24410749 

  122. Tsai Y.-T. Cheng P.-C. Pan T.-M. ( 2014 ). Anti-obesity effects of gut microbiota are associated with lactic acid bacteria. Appl. Microbiol. Biotechnol. 98 1 – 10 . 10.1042/CS20130339 24232731 

  123. Turnbaugh P. J. Ley R. E. Mahowald M. A. Magrini V. Mardis E. R. Gordon J. I. ( 2006 ). An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 444 1027 – 1131 . 10.1007/s00253-013-5346-3 17183312 

  124. Turta O. Rautava S. ( 2016 ). Antibiotics, obesity and the link to microbes-what are we doing to our children? BMC Med. 14 : 57 10.1186/s12916-016-0605-7 

  125. Velagapudi V. R. Hezaveh R. Reigstad C. S. Gopalacharyulu P. Yetukuri L. Islam S. ( 2010 ). The gut microbiota modulates host energy and lipid metabolism in mice. J. Lipid Res. 51 1101 – 1112 . 10.1194/jlr.M002774 20040631 

  126. Vijay-Kumar M. Aitken J. D. Carvalho F. A. Cullender T. C. Mwangi S. Srinivasan S. ( 2010 ). Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science 328 228 – 231 . 10.1126/science.1179721 20203013 

  127. Villena J. Kitazawa H. ( 2014 ). Modulation of intestinal TLR4-inflammatory signaling pathways by probiotic microorganisms: lessons learned from Lactobacillus jensenii TL2937. Front. Immunol. 4 : 512 10.3389/fimmu.2013.00512 

  128. Vucenik I. Stains J. P. ( 2012 ). Obesity and cancer risk: evidence, mechanisms, and recommendations. Ann. N. Y. Acad. Sci. 1271 37 – 43 . 10.1111/j.1749-6632.2012.06750.x 23050962 

  129. Wang H. Eckel R. H. ( 2009 ). Lipoprotein lipase: from gene to obesity. Am. J. Physiol. Endocrinol. Metab. 297 E271 – E288 . 10.1152/ajpendo.90920.2008 19318514 

  130. Wang Y. C. McPherson K. Marsh T. Gortmaker S. L. Brown M. ( 2011 ). Health and economic burden of the projected obesity trends in the USA and the UK. Lancet 378 815 – 825 . 10.1016/S0140-6736(11)60814-3 21872750 

  131. Wang Z. Xiao G. Yao Y. Guo S. Lu K. Sheng Z. ( 2006 ). The role of bifidobacteria in gut barrier function after thermal injury in rats. J. Trauma Acute Care Surg. 61 650 – 657 . 10.1016/S0140-6736(11)60814-3 

  132. Withrow D. Alter D. ( 2011 ). The economic burden of obesity worldwide: a systematic review of the direct costs of obesity. Obes. Rev. 12 131 – 141 . 10.1111/j.1467-789X.2009.00712.x 20122135 

  133. Xiong Y. Miyamoto N. Shibata K. Valasek M. A. Motoike T. Kedzierski R. M. ( 2004 ). Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41. Proc. Natl. Acad. Sci. U.S.A. 101 1045 – 1050 . 10.1111/j.1467-789X.2009.00712.x 14722361 

  134. Yadav H. Lee J. H. Lloyd J. Walter P. Rane S. G. ( 2013 ). Beneficial metabolic effects of a probiotic via butyrate-induced GLP-1 hormone secretion. J. Biol. Chem. 288 25088 – 25097 . 10.1074/jbc.M113.452516 23836895 

  135. Yadav R. Singh P. K. Puniya A. K. Shukla P. ( 2016a ). Catalytic interactions andmolecular docking of bile salt hydrolase (BSH) from L. plantarum RYPR1 and itsprebiotic utilization. Front. Microbiol. 7 : 2116 10.3389/fmicb.2016.02116 

  136. Yadav R. Singh P. K. Shukla P. ( 2016b ). Metabolic engineering for probiotics and their genome-wide expression profiling. Curr. Protein Pept. Sci. 10.2174/1389203718666161111130157 [Epub ahead of print] . 

  137. Yin Y.-N. Yu Q.-F. Fu N. Liu X.-W. Lu F.-G. ( 2010 ). Effects of four Bifidobacteria on obesity in high-fat diet induced rats. World J. Gastroenterol. 16 3394 – 3401 . 10.3748/wjg.v16.i27.3394 20632441 

  138. Zaibi M. S. Stocker C. J. O’Dowd J. Davies A. Bellahcene M. Cawthorne M. A. ( 2010 ). Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids. FEBS Lett. 584 2381 – 2386 . 10.1016/j.febslet.2010.04.027 20399779 

  139. Zhou J. Martin R. J. Tulley R. T. Raggio A. M. McCutcheon K. L. Shen L. ( 2008 ). Dietary resistant starch upregulates total GLP-1 and PYY in a sustained day-long manner through fermentation in rodents. Am. J. Physiol. Endocrinol. Metab. 295 E1160 – E1166 . 10.1152/ajpendo.90637.2008 18796545 

  140. Zimmer J. Lange B. Frick J.-S. Sauer H. Zimmermann K. Schwiertz A. ( 2012 ). A vegan or vegetarian diet substantially alters the human colonic faecal microbiota. Eur. J. Clin. Nutr. 66 53 – 60 . 10.1038/ejcn.2011.141 21811294 

활용도 분석정보

상세보기
다운로드
내보내기

활용도 Top5 논문

해당 논문의 주제분야에서 활용도가 높은 상위 5개 콘텐츠를 보여줍니다.
더보기 버튼을 클릭하시면 더 많은 관련자료를 살펴볼 수 있습니다.

관련 콘텐츠

오픈액세스(OA) 유형

GOLD

오픈액세스 학술지에 출판된 논문

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로