[논문]The Drug Adherence and Treatment Effect of the Paliperidone Long Acting Injection

Kim, Harin; Lee, Jungsun; Kim, Changyoon; Joo, Yeonho

doi:10.4306/jknpa.2015.54.1.69

[국내논문] The Drug Adherence and Treatment Effect of the Paliperidone Long Acting Injection
팔리페리돈 장기지속형주사제의 약물 순응도와 치료 효과 원문보기

神經精神醫學 = Journal of the Korean neuropsychiatric association, v.54 no.1, 2015년, pp.69 - 75

Kim, Harin (Department of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine) , Lee, Jungsun (Department of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine) , Kim, Changyoon (Department of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine) , Joo, Yeonho (Department of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine)

Abstract ▼ AI-Helper

ObjectivesThe aim of this study was to examine the drug adherence and treatment effect of the paliperidone long acting injection (LAI) in patients with schizophrenia or other psychotic disorders.MethodsWe reviewed the medical charts of patients who were prescribed paliperidone LAI from January 2010 to April 2014. Date of each injection, last observation, and first admission after use of the drug were obtained. Kaplan-Meier survival analysis was used for calculation of drug adherence. The dose of paliperidone LAI, concurrent oral antipsychotics, and anticholinergic agent was also obtained. Antipsychotics dose was calculated as olanzapine equivalent dose.ResultsThe drug adherence of the paliperidone LAI on day 365 was 65%. The reasons for all cause discontinuation were follow-up loss, no effect, poor insight, rejection, extrapyramidal symptom, pain, etc. A total dose of 9.1 mg of oral antipsychotics was decreased, while the dose of anticholinergic agent was increased.ConclusionThe drug adherence of the paliperidone LAI was 65%, which was concordant with previous studies. The dose of concurrent oral antipsychotics was increased, while the dose of anticholinergic agent was decreased.

Keyword

참고문헌 (26)

Schizophr Bull Fatemi 35 528 2009 10.1093/schbul/sbn187

상세보기
CNS Spectr Lieberman 12 3 Suppl 4 1 2007 10.1017/S1092852900026328

상세보기
J Psychiatr Pract Velligan 16 306 2010 10.1097/01.pra.0000388626.98662.a0

상세보기
J Clin Psychopharmacol Lambert 30 565 2010 10.1097/JCP.0b013e3181f058a0

상세보기
J Clin Psychiatry Velligan 70 Suppl 4 1 2009
Eur Neuropsychopharmacol Bhanji 14 87 2004 10.1016/S0924-977X(03)00109-3

상세보기
J Clin Psychiatry Kishimoto 74 957 2013 10.4088/JCP.13r08440

상세보기
Br J Psychiatry Suppl Fleischhacker 52 S29 2009 10.1192/bjp.195.52.s29

상세보기
Four-week iloperidone depot injectable: safety and pharmacokinetic profile in patients with schizophrenia and schizoaffective disorder Hill 2008
Int J Clin Pract Citrome 63 140 2009 10.1111/j.1742-1241.2008.01900.x

상세보기
J Clin Psychopharmacol Pandina 30 235 2010 10.1097/JCP.0b013e3181dd3103

상세보기
Int Clin Psychopharmacol Gopal 25 247 2010 10.1097/YIC.0b013e32833948fa

상세보기
Int J Neuropsychopharmacol Kramer 13 635 2010 10.1017/S1461145709990988

상세보기
Schizophr Res Hough 116 107 2010 10.1016/j.schres.2009.10.026

상세보기
Ann Gen Psychiatry Alphs 10 12 2011 10.1186/1744-859X-10-12

상세보기
Korean J Psychopharmacol Lee 22 Suppl 2 S49 2011
Korean J Psychopharmacol Kim 23 17 2012
Am J Psychiatry Gardner 167 686 2010 10.1176/appi.ajp.2009.09060802

상세보기
Acta Psychiatr Scand Attard 130 46 2014 10.1111/acps.12201

상세보기
Int J Neuropsychopharmacol Taylor 9 685 2006 10.1017/S1461145705006309

상세보기
N Engl J Med Lieberman 353 1209 2005 10.1056/NEJMoa051688

상세보기
Eur Neuropsychopharmacol Moritz 24 1745 2014 10.1016/j.euroneuro.2014.09.008

상세보기
Neuropsychiatr Dis Treat Gopal 9 1381 2013 10.2147/NDT.S49944

상세보기
Prim Care Companion J Clin Psychiatry Leo 2 194 2000 10.4088/PCC.v02n0601

상세보기
Principle and practice of long-acting injectable antipsychotics Kim 256 2012
Pharmacotherapy Gentile 33 1087 2013 10.1002/phar.1313

상세보기

활용도 분석정보

상세보기

다운로드

내보내기

활용도 Top5 논문

해당 논문의 주제분야에서 활용도가 높은 상위 5개 콘텐츠를 보여줍니다.
더보기 버튼을 클릭하시면 더 많은 관련자료를 살펴볼 수 있습니다.

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관 관리번호, 논문명, 대등논문명, 저자 , 저널/프로시딩명, 발행기관, 발행년, 발행언어, 권, 호, 시작페이지, 끝페이지, ISBN, ISSN, 주제분야, 키워드, 초록(한글), 초록(영문), 저자(소속기관)
저장형식	Text(ASCII format) Excel format RefWorks Direct Export RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증