참고문헌 (55)

1. Blood Park 127 3312 2016 10.1182/blood-2016-02-629063 CD19-targeted CAR T-cell therapeutics for hematologic malignancies: interpreting clinical outcomes to date 

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2. Blood Louis 118 6050 2011 10.1182/blood-2011-05-354449 Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma 

   상세보기

3. Cancer Res Slaney 74 7168 2014 10.1158/0008-5472.CAN-14-2458 Trafficking of T cells into tumors 

   상세보기

4. Nat Commun Koyama 7 10501 2016 10.1038/ncomms10501 Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints 

   상세보기

5. Immunity Schietinger 45 389 2016 10.1016/j.immuni.2016.07.011 Tumor-specific T cell dysfunction is a dynamic antigen-driven differentiation program initiated early during tumorigenesis 

   상세보기

6. Nat Med Chen 21 327 2015 10.1038/nm.3831 Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection 

   상세보기

7. Nat Med Fry 24 20 2018 10.1038/nm.4441 CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy 

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8. Cancer Discov Sotillo 5 1282 2015 10.1158/2159-8290.CD-15-1020 Convergence of acquired mutations and alternative splicing of CD19 enables resistance to CART-19 immunotherapy 

   상세보기

9. Sci Rep Rupp 7 737 2017 10.1038/s41598-017-00462-8 CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells 

   상세보기

10. Science Hui 355 1428 2017 10.1126/science.aaf1292 T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition 

    상세보기

11. Cancer Res Menger 76 2087 2016 10.1158/0008-5472.CAN-15-3352 TALEN-mediated inactivation of PD-1 in tumor-reactive lymphocytes promotes intratumoral T-cell persistence and rejection of established tumors 

    상세보기

12. Clin Cancer Res Taube 20 5064 2014 10.1158/1078-0432.CCR-13-3271 Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy 

    상세보기

13. J Leukoc Biol Arumugam 98 703 2015 10.1189/jlb.2HIMA1214-578R TCR signaling intensity controls CD8+ T cell responsiveness to TGF-beta 

    상세보기

14. Front Immunol Wehbi 7 222 2016 10.3389/fimmu.2016.00222 Molecular mechanisms for cAMP-mediated immunoregulation in T cells - Role of anchored protein kinase a signaling units 

    상세보기

15. Cancer Chemother Biol Response Modif Ma 20 315 2002 Genetically engineered T cells as adoptive immunotherapy of cancer 

16. Front Cell Dev Biol Riese 4 108 2016 10.3389/fcell.2016.00108 Diacylglycerol kinases (DGKs): novel targets for improving T cell activity in cancer 

    상세보기

17. Int J Cancer Prinz 135 1832 2014 10.1002/ijc.28837 NK-cell dysfunction in human renal carcinoma reveals diacylglycerol kinase as key regulator and target for therapeutic intervention 

    상세보기

18. J Immunol Prinz 188 5990 2012 10.4049/jimmunol.1103028 High DGK-alpha and disabled MAPK pathways cause dysfunction of human tumor-infiltrating CD8+ T cells that is reversible by pharmacologic intervention 

    상세보기

19. Clin Cancer Res Moon 20 4262 2014 10.1158/1078-0432.CCR-13-2627 Multifactorial T-cell hypofunction that is reversible can limit the efficacy of chimeric antigen receptor-transduced human T cells in solid tumors 

    상세보기

20. Nat Immunol Zhong 4 882 2003 10.1038/ni958 Enhanced T cell responses due to diacylglycerol kinase ζ deficiency 

    상세보기

21. EBioMedicine Andrada 19 39 2017 10.1016/j.ebiom.2017.04.024 Diacylglycerol kinase zeta limits cytokine-dependent expansion of CD8+ T cells with broad antitumor capacity 

    상세보기

22. Sci Signal Joshi 6 ra102 2013 10.1126/scisignal.2004373 The zeta isoform of diacylglycerol kinase plays a predominant role in regulatory T cell development and TCR-mediated ras signaling 

    상세보기

23. Cancer Res Riese 73 3566 2013 10.1158/0008-5472.CAN-12-3874 Enhanced effector responses in activated CD8+ T cells deficient in diacylglycerol kinases 

    상세보기

24. Oncotarget Yang 7 33744 2016 10.18632/oncotarget.8164 Unexpected positive control of NFkappaB and miR-155 by DGKalpha and zeta ensures effector and memory CD8+ T cell differentiation 

    상세보기

25. Front Cell Dev Biol Singh 4 96 2016 10.3389/fcell.2016.00096 The immunomodulatory functions of diacylglycerol kinase zeta 

    상세보기

26. J Exp Med Liu 204 781 2007 10.1084/jem.20061856 Diacylglycerol kinase ζ regulates microbial recognition and host resistance to Toxoplasma gondii 

    상세보기

27. Front Cell Dev Biol Noessner 5 16 2017 10.3389/fcell.2017.00016 DGK-alpha: a checkpoint in cancer-mediated immuno-inhibition and target for immunotherapy 

    상세보기

28. Pharmacology Sato 92 99 2013 10.1159/000351849 Evaluations of the selectivities of the diacylglycerol kinase inhibitors R59022 and R59949 among diacylglycerol kinase isozymes using a new non-radioactive assay method 

    상세보기

29. Sci Transl Med O'Rourke 9 2017 A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma 

    상세보기

30. Nat Med Rapoport 21 914 2015 10.1038/nm.3910 NY-ESO-1-specific TCR-engineered T cells mediate sustained antigen-specific antitumor effects in myeloma 

    상세보기

31. Clin Cancer Res Sampson 20 972 2014 10.1158/1078-0432.CCR-13-0709 EGFRvIII mCAR-modified T-cell therapy cures mice with established intracerebral glioma and generates host immunity against tumor-antigen loss 

    상세보기

32. Nat Methods Kim 12 237 2015 10.1038/nmeth.3284 Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells 

    상세보기

33. J Immunol Shin 188 2111 2012 10.4049/jimmunol.1102265 Differential regulation of primary and memory CD8 T cell immune responses by diacylglycerol kinases 

    상세보기

34. Front Oncol Perng 5 153 2015 10.3389/fonc.2015.00153 Immunosuppressive mechanisms of malignant gliomas: parallels at non-CNS sites 

    상세보기

35. Nat Immunol Zha 7 1166 2006 10.1038/ni1394 T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-alpha 

    상세보기

36. Nat Immunol Olenchock 7 1174 2006 10.1038/ni1400 Disruption of diacylglycerol metabolism impairs the induction of T cell anergy 

    상세보기

37. J Biol Chem Alonso 280 28439 2005 10.1074/jbc.M501112200 Diacylglycerol kinase alpha regulates the secretion of lethal exosomes bearing Fas ligand during activation-induced cell death of T lymphocytes 

    상세보기

38. Mol Ther Walker 25 2189 2017 10.1016/j.ymthe.2017.06.008 Tumor antigen and receptor densities regulate efficacy of a chimeric antigen receptor targeting anaplastic lymphoma kinase 

    상세보기

39. Nat Med Gattinoni 17 1290 2011 10.1038/nm.2446 A human memory T cell subset with stem cell-like properties 

    상세보기

40. J Immunother Cancer Ohno 1 21 2013 10.1186/2051-1426-1-21 Expression of miR-17-92 enhances anti-tumor activity of T-cells transduced with the anti-EGFRvIII chimeric antigen receptor in mice bearing human GBM xenografts 

    상세보기

41. Sci Transl Med Johnson 7 275ra22 2015 10.1126/scitranslmed.aaa4963 Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastoma 

    상세보기

42. Sci Rep Su 6 20070 2016 10.1038/srep20070 CRISPR-Cas9 mediated efficient PD-1 disruption on human primary T cells from cancer patients 

    상세보기

43. J Immunol Baldanzi 187 5941 2011 10.4049/jimmunol.1002476 SAP-mediated inhibition of diacylglycerol kinase alpha regulates TCR-induced diacylglycerol signaling 

    상세보기

44. J Cell Physiol Tu-Sekine 220 548 2009 10.1002/jcp.21813 Regulation of DGK-theta 

    상세보기

45. Am J Hum Genet Leach 80 792 2007 10.1086/513019 Disruption of diacylglycerol kinase delta (DGKD) associated with seizures in humans and mice 

    상세보기

46. Proc Natl Acad Sci U S A Guo 105 11909 2008 10.1073/pnas.0711856105 Synergistic control of T cell development and tumor suppression by diacylglycerol kinase alpha and zeta 

    상세보기

47. Neurosci Lett Ali 372 190 2004 10.1016/j.neulet.2004.09.052 Selective translocation of diacylglycerol kinase zeta in hippocampal neurons under transient forebrain ischemia 

    상세보기

48. Genome Res Kim 28 367 2018 10.1101/gr.231936.117 CRISPR RNAs trigger innate immune responses in human cells 

    상세보기

49. Nat Biotechnol Hendel 33 985 2015 10.1038/nbt.3290 Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells 

    상세보기

50. Genome Res Kim 24 1012 2014 10.1101/gr.171322.113 Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins 

    상세보기

51. Front Med Zhang 11 554 2017 10.1007/s11684-017-0543-6 CRISPR-Cas9 mediated LAG-3 disruption in CAR-T cells 

    상세보기

52. Sci Signal Merida 8 re6 2015 10.1126/scisignal.aaa0974 Redundant and specialized roles for diacylglycerol kinases alpha and zeta in the control of T cell functions 

    상세보기

53. Science Sen 354 1165 2016 10.1126/science.aae0491 The epigenetic landscape of T cell exhaustion 

    상세보기

54. Cancer Discov Shum 7 1238 2017 10.1158/2159-8290.CD-17-0538 Constitutive signaling from an engineered IL7 receptor promotes durable tumor elimination by tumor-redirected T cells 

    상세보기

55. Oncotarget Filley 8 91779 2017 10.18632/oncotarget.21586 Recurrent glioma clinical trial, CheckMate-143: the game is not over yet 

    상세보기

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