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Slas technology, v.22 no.2, 2017년, pp.153 - 162
Worzella, Tracy (Promega Corporation, R&D Department, Madison, WI, USA) , Butzler, Matt (Promega Corporation, R&D Department, Madison, WI, USA) , Hennek, Jacquelyn (Promega Corporation, R&D Department, Madison, WI, USA) , Hanson, Seth (Gilson, Inc., Middleton, WI, USA) , Simdon, Laura (Gilson, Inc., Middleton, WI, USA) , Goueli, Said (Promega Corporation, R&D Department, Madison, WI, USA) , Cowan, Cris (Promega Corporation, R&D Department, Madison, WI, USA) , Zegzouti, Hicham (Promega Corporation, R&D Department, Madison, WI, USA)
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Kinase profiling during drug discovery is a necessary process to confirm inhibitor selectivity and assess off-target activities. However, cost and logistical limitations prevent profiling activities from being performed in-house. We describe the development of an automated and flexible kinase profil...
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