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NTIS 바로가기International journal of molecular sciences, v.18 no.12, 2017년, pp.2635 -
Ihn, Hye Jung (Department of Oral Pathology and Regenerative Medicine, School of Dentistry, Institute for Hard Tissue and Biotooth Regeneration, Kyungpook National University, Daegu 41940, Korea) , Kim, Ju Ang (hjpihn@hanmail.net (H.J.I.)) , Cho, Hye Sung (kkangjin5@hanmail.net (J.A.K.)) , Shin, Hong-In (uricomet@knu.ac.kr (H.S.C.)) , Kim, Gi-Young (hishin@knu.ac.kr (H.-I.S.)) , Choi, Yung Hyun (Department of Oral Pathology and Regenerative Medicine, School of Dentistry, Institute for Hard Tissue and Biotooth Regeneration, Kyungpook National University, Daegu 41940, Korea) , Jeon, You-Jin (hjpihn@hanmail.net (H.J.I.)) , Park, Eui Kyun (kkangjin5@hanmail.net (J.A.K.))
Marine algae possess a variety of beneficial effects on human health. In this study, we investigated whether diphlorethohydroxycarmalol (DPHC), isolated from Ishige okamurae, a brown alga, suppresses receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclast differentiation. DPH...
1. Manolagas S.C. Jilka R.L. Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis N. Engl. J. Med. 1995 332 305 311 10.1056/NEJM199502023320506 7816067
2. Ralston S.H. Layfield R. Pathogenesis of paget disease of bone Calcif. Tissue Int. 2012 91 97 113 10.1007/s00223-012-9599-0 22543925
3. Mundy G.R. Osteoporosis and inflammation Nutr. Rev. 2007 65 S147 S151 10.1301/nr.2007.dec.S147-S151 18240539
4. Roodman G.D. Biology of osteoclast activation in cancer J. Clin. Oncol. 2001 19 3562 3571 10.1200/JCO.2001.19.15.3562 11481364
5. Lacey D.L. Timms E. Tan H.L. Kelley M.J. Dunstan C.R. Burgess T. Elliott R. Colombero A. Elliott G. Scully S. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation Cell 1998 93 165 176 10.1016/S0092-8674(00)81569-X 9568710
6. Tanaka S. Takahashi N. Udagawa N. Tamura T. Akatsu T. Stanley E.R. Kurokawa T. Suda T. Macrophage colony-stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors J. Clin. Investig. 1993 91 257 263 10.1172/JCI116179 8423223
7. Asagiri M. Takayanagi H. The molecular understanding of osteoclast differentiation Bone 2007 40 251 264 10.1016/j.bone.2006.09.023 17098490
8. Teitelbaum S.L. Ross F.P. Genetic regulation of osteoclast development and function Nat. Rev. Genet. 2003 4 638 649 10.1038/nrg1122 12897775
9. Heo S.J. Kim J.P. Jung W.K. Lee N.H. Kang H.S. Jun E.M. Park S.H. Kang S.M. Lee Y.J. Park P.J. Identification of chemical structure and free radical scavenging activity of diphlorethohydroxycarmalol isolated from a brown alga, ishige okamurae J. Microbiol. Biotechnol. 2008 18 676 681 18467860
10. Heo S.J. Hwang J.Y. Choi J.I. Han J.S. Kim H.J. Jeon Y.J. Diphlorethohydroxycarmalol isolated from ishige okamurae, a brown algae, a potent alpha-glucosidase and alpha-amylase inhibitor, alleviates postprandial hyperglycemia in diabetic mice Eur. J. Pharmacol. 2009 615 252 256 10.1016/j.ejphar.2009.05.017 19482018
11. Kang N.J. Han S.C. Kang G.J. Koo D.H. Koh Y.S. Hyun J.W. Lee N.H. Ko M.H. Kang H.K. Yoo E.S. Diphlorethohydroxycarmalol inhibits interleukin-6 production by regulating nf-kappab, stat5 and socs1 in lipopolysaccharide-stimulated raw264.7 cells Mar. Drugs 2015 13 2141 2157 10.3390/md13042141 25871292
12. Kotake-Nara E. Asai A. Nagao A. Neoxanthin and fucoxanthin induce apoptosis in pc-3 human prostate cancer cells Cancer Lett. 2005 220 75 84 10.1016/j.canlet.2004.07.048 15737690
13. Mayer A.M. Hamann M.T. Marine pharmacology in 2001–2002: Marine compounds with anthelmintic, antibacterial, anticoagulant, antidiabetic, antifungal, anti-inflammatory, antimalarial, antiplatelet, antiprotozoal, antituberculosis, and antiviral activities; affecting the cardiovascular, immune and nervous systems and other miscellaneous mechanisms of action Comp. Biochem. Physiol. C Toxicol. Pharmacol. 2005 140 265 286 15919242
14. Heo S.J. Hwang J.Y. Choi J.I. Lee S.H. Park P.J. Kang D.H. Oh C. Kim D.W. Han J.S. Jeon Y.J. Protective effect of diphlorethohydroxycarmalol isolated from ishige okamurae against high glucose-induced-oxidative stress in human umbilical vein endothelial cells Food Chem. Toxicol. 2010 48 1448 1454 10.1016/j.fct.2010.02.025 20176069
15. Feng S. Deng L. Chen W. Shao J. Xu G. Li Y.P. Atp6v1c1 is an essential component of the osteoclast proton pump and in f-actin ring formation in osteoclasts Biochem. J. 2009 417 195 203 10.1042/BJ20081073 18657050
16. Kwak H.B. Kim J.Y. Kim K.J. Choi M.K. Kim J.J. Kim K.M. Shin Y.I. Lee M.S. Kim H.S. Kim J.W. Risedronate directly inhibits osteoclast differentiation and inflammatory bone loss Biol. Pharm. Bull. 2009 32 1193 1198 10.1248/bpb.32.1193 19571384
17. Nishikawa M. Akatsu T. Katayama Y. Yasutomo Y. Kado S. Kugal N. Yamamoto M. Nagata N. Bisphosphonates act on osteoblastic cells and inhibit osteoclast formation in mouse marrow cultures Bone 1996 18 9 14 10.1016/8756-3282(95)00426-2 8717530
18. Florencio-Silva R. Sasso G.R. Sasso-Cerri E. Simoes M.J. Cerri P.S. Biology of bone tissue: Structure, function, and factors that influence bone cells BioMed Res. Int. 2015 2015 421746 10.1155/2015/421746 26247020
19. Sims N.A. Martin T.J. Coupling signals between the osteoclast and osteoblast how are messages transmitted between these temporary visitors to the bone surface? Front. Endocrinol. 2015 6 10.3389/fendo.2015.00041 25852649
20. Sivolella S. Lumachi F. Stellini E. Favero L. Denosumab and anti-angiogenetic drug-related osteonecrosis of the jaw: An uncommon but potentially severe disease Anticancer Res. 2013 33 1793 1797 23645723
21. Che C.T. Wong M.S. Lam C.W. Natural products from Chinese medicines with potential benefits to bone health Molecules 2016 21 239 10.3390/molecules21030239 26927052
22. Kim K. Kim J.H. Lee J. Jin H.M. Lee S.H. Fisher D.E. Kook H. Kim K.K. Choi Y. Kim N. Nuclear factor of activated t cells c1 induces osteoclast-associated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-mediated osteoclastogenesis J. Biol. Chem. 2005 280 35209 35216 10.1074/jbc.M505815200 16109714
23. Kim Y. Sato K. Asagiri M. Morita I. Soma K. Takayanagi H. Contribution of nuclear factor of activated t cells c1 to the transcriptional control of immunoreceptor osteoclast-associated receptor but not triggering receptor expressed by myeloid cells-2 during osteoclastogenesis J. Biol. Chem. 2005 280 32905 32913 10.1074/jbc.M505820200 16046394
24. Matsumoto M. Kogawa M. Wada S. Takayanagi H. Tsujimoto M. Katayama S. Hisatake K. Nogi Y. Essential role of p38 mitogen-activated protein kinase in cathepsin k gene expression during osteoclastogenesis through association of nfatc1 and pu.1 J. Biol. Chem. 2004 279 45969 45979 10.1074/jbc.M408795200 15304486
25. Takayanagi H. Kim S. Koga T. Nishina H. Isshiki M. Yoshida H. Saiura A. Isobe M. Yokochi T. Inoue J. Induction and activation of the transcription factor nfatc1 (nfat2) integrate rankl signaling in terminal differentiation of osteoclasts Dev. Cell 2002 3 889 901 10.1016/S1534-5807(02)00369-6 12479813
26. Johnson R.S. Spiegelman B.M. Papaioannou V. Pleiotropic effects of a null mutation in the c-fos proto-oncogene Cell 1992 71 577 586 10.1016/0092-8674(92)90592-Z 1423615
27. Takatsuna H. Asagiri M. Kubota T. Oka K. Osada T. Sugiyama C. Saito H. Aoki K. Ohya K. Takayanagi H. Inhibition of rankl-induced osteoclastogenesis by (−)-dhmeq, a novel nf-kappab inhibitor, through downregulation of nfatc1 J. Bone Miner. Res. 2005 20 653 662 10.1359/JBMR.041213 15765185
28. Wang Z.Q. Ovitt C. Grigoriadis A.E. Mohle-Steinlein U. Ruther U. Wagner E.F. Bone and haematopoietic defects in mice lacking c-fos Nature 1992 360 741 745 10.1038/360741a0 1465144
29. Ihn H.J. Lee D. Lee T. Kim S.H. Shin H.I. Bae Y.C. Hong J.M. Park E.K. Inhibitory effects of kp-a159, a thiazolopyridine derivative, on osteoclast differentiation, function, and inflammatory bone loss via suppression of rankl-induced map kinase signaling pathway PLoS ONE 2015 10 e0142201 10.1371/journal.pone.0142201 26536233
30. Ihn H.J. Lee T. Kim J.A. Lee D. Kim N.D. Shin H.I. Bae Y.C. Park E.K. Ocli-023, a novel pyrimidine compound, suppresses osteoclastogenesis in vitro and alveolar bone resorption in vivo PLoS ONE 2017 12 e0170159 10.1371/journal.pone.0170159 28085946
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