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NTIS 바로가기Medicines : open access journal, v.5 no.4, 2018년, pp.127 -
Tungmunnithum, Duangjai (Department of Pharmaceutical Botany, Faculty of Pharmacy, Mahidol University, Bangkok 10400, Thailand) , Pinthong, Darawan (Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand) , Hano, Christophe (Darawan.pin@mahidol.ac.th)
Nelumbo nucifera Gaertn. has been used as an important ingredient for traditional medicines since ancient times, especially in Asian countries. Nowadays, many new or unknown phytochemical compounds from N. nucifera are still being discovered. Most of the current research about pharmacological activi...
1. Chen S. Zheng Y. Fang J.B. Liu Y.L. Li S.H. Flavonoids in lotus (Nelumbo) leaves evaluated by HPLC-MSnat the germplasm level Food Res. Int. 2013 54 796 803 10.1016/j.foodres.2013.08.031
2. Sheikh S.A. Ethno-medicinal uses and pharmacological activities of lotus ( Nelumbo nucifera ) J. Med. Plants Stud. 2014 2 42 46
3. Deng J. Chen S. Yin X. Wang K. Liu Y. Li S. Yang P. Systematic qualitative and quantitative assessment of anthocyanins, flavones and flavonols in the petals of 108 lotus ( Nelumbo nucifera ) cultivars Food Chem. 2013 139 307 312 10.1016/j.foodchem.2013.02.010 23561110
4. Paudel K.R. Panth N. Phytochemical profile and biological activity of Nelumbo nucifera Evid.-Based Complement. Altern. Med. 2015 2015 10.1155/2015/789124 27057194
5. Lee J.S. Shukla S. Kim J.A. Kim M. Anti-angiogenic effect of nelumbo nucifera leaf extracts in human umbilical vein endothelial cells with antioxidant potential PLoS ONE 2015 10 10.1371/journal.pone.0118552 25714482
6. Zhu M.Z. Wu W. Jiao L.L. Yang P.F. Guo M.Q. Analysis of flavonoids in lotus ( Nelumbo nucifera ) leaves and their antioxidant activity using macroporous resin chromatography coupled with LC-MS/MS and antioxidant biochemical assays Molecules 2015 20 10553 10565 10.3390/molecules200610553 26060918
7. Rai S. Wahile A. Mukherjee K. Saha B.P. Mukherjee P.K. Antioxidant activity of Nelumbo nucifera (sacred lotus) seeds J. Ethnopharmacol. 2006 104 322 327 10.1016/j.jep.2005.09.025 16239089
9. Lin H.Y. Kuo Y.H. Lin Y.L. Chiang W. Antioxidative effect and active components from leaves of lotus ( Nelumbo nucifera ) J. Agric. Food Chem. 2009 57 6623 6629 10.1021/jf900950z 19572539
10. Courts F.L. Williamson G. The occurrence, fate and biological activities of c-glycosyl flavonoids in the human diet Crit. Rev. Food Sci. Nutr. 2015 55 1352 1367 10.1080/10408398.2012.694497 24915338
11. Lee B. Kwon M. Choi J.S. Jeong H.O. Chung H.Y. Kim H.-R. Kaempferol Isolated from Nelumbo nucifera Inhibits Lipid Accumulation and Increases Fatty Acid Oxidation Signaling in Adipocytes J. Med. Food 2015 18 1363 1370 10.1089/jmf.2015.3457 26280739
12. Zhu Y.T. Jia Y.W. Liu Y.M. Liang J. Ding L.S. Liao X. Lipase ligands in nelumbo nucifera leaves and study of their binding mechanism J. Agric. Food Chem. 2014 62 10679 10686 10.1021/jf503687e 25328123
13. Bin X. Jin W. Wenqing W. Chunyang S. Xiaolong H. Jianguo F. Nelumbo nucifera alkaloid inhibits 3T3-L1 preadipocyte differentiation and improves high-fat diet-induced obesity and body fat accumulation in rats J. Med. Plant. Res. 2011 5 2021 2028
14. Chang C.H. Ou T.T. Yang M.Y. Huang C.C. Wang C.J. Nelumbo nucifera Gaertn leaves extract inhibits the angiogenesis and metastasis of breast cancer cells by downregulation connective tissue growth factor (CTGF) mediated PI3K/AKT/ERK signaling J. Ethnopharmacol. 2016 188 111 122 10.1016/j.jep.2016.05.012 27178635
15. Sharma B.R. Kim M.S. Rhyu D.Y. Nelumbo Nucifera leaf extract attenuated pancreatic beta-cells toxicity induced by interleukin-1beta and interferon-gamma, and increased insulin secrection of pancreatic beta-cells in streptozotocin-induced diabetic rats J. Tradit. Chin. Med. 2016 36 71 77 10.1016/S0254-6272(16)30011-5 26946622
16. Wu C.H. Yang M.Y. Lee Y.J. Wang C.J. Nelumbo nucifera leaf polyphenol extract inhibits breast cancer cells metastasis in vitro and in vivo through PKCα targeting J. Funct. Foods 2017 37 480 490 10.1016/j.jff.2017.08.021
17. Sergent T. Vanderstraeten J. Winand J. Beguin P. Schneider Y.J. Phenolic compounds and plant extracts as potential natural anti-obesity substances Food Chem. 2012 135 68 73 10.1016/j.foodchem.2012.04.074
18. Rajput M.A. Khan R.A. Phytochemical screening, acute toxicity, anxiolytic and antidepressant activities of the Nelumbo nucifera fruit Metab. Brain Dis. 2017 32 743 749 10.1007/s11011-017-9963-x 28144887
19. Mongkolrat S. Palanuvej C. Ruangrungsi N. Quality assessment and liriodenine quantification of Nelumbo nucifera dried leaf in Thailand Pharmacogn. J. 2012 4 24 28 10.5530/pj.2012.32.5
20. Feng C.Y. Li S.S. Yin D.D. Zhang H.J. Tian D.K. Wu Q. Wang L.J. Su S. Wang L.S. Rapid determination of flavonoids in plumules of sacred lotus cultivars and assessment of their antioxidant activities Ind. Crops Prod. 2016 87 96 104 10.1016/j.indcrop.2016.04.030
21. Lim S.S. Jung Y.J. Hyun S.K. Lee Y.S. Choi J.S. Rat lens aldose reductase inhibitory constituents of Nelumbo nucifera stamens Phyther. Res. 2006 20 825 830 10.1002/ptr.1847 16881021
22. Hofer B. Recent developments in the enzymatic O-glycosylation of flavonoids Appl. Microbiol. Biotechnol. 2016 100 4269 4281 10.1007/s00253-016-7465-0 27029191
23. Wu H.M. Kao C.L. Huang S.C. Li W.J. Li H.T. Chen C.Y. Secondary Metabolites from the Stems of Nelumbo nucifera cv. Rosa-plena Chem. Nat. Compd. 2017 53 797 798 10.1007/s10600-017-2126-9
24. Chen S. Fang L. Xi H. Guan L. Fang J. Liu Y. Wu B. Li S. Simultaneous qualitative assessment and quantitative analysis of flavonoids in various tissues of lotus ( Nelumbo nucifera ) using high performance liquid chromatography coupled with triple quad mass spectrometry Anal. Chim. Acta 2012 724 127 135 10.1016/j.aca.2012.02.051 22483220
25. Zhu F. Structures, properties, and applications of lotus starches Food Hydrocoll. 2017 63 332 348 10.1016/j.foodhyd.2016.08.034
26. Zhu M. Liu T. Zhang C. Guo M. Flavonoids of Lotus ( Nelumbo nucifera ) Seed Embryos and Their Antioxidant Potential J. Food Sci. 2017 82 1834 1841 10.1111/1750-3841.13784 28631810
27. Huang B. Ban X. He J. Tong J. Tian J. Wang Y. Hepatoprotective and antioxidant activity of ethanolic extracts of edible lotus ( Nelumbo nucifera Gaertn.) leaves Food Chem. 2010 120 873 878 10.1016/j.foodchem.2009.11.020
28. Liu Y. Ma S.S. Ibrahim S.A. Li E.H. Yang H. Huang W. Identification and antioxidant properties of polyphenols in lotus seed epicarp at different ripening stages Food Chem. 2015 185 159 164 10.1016/j.foodchem.2015.03.117 25952854
29. Huang B. Zhu L. Liu S. Li D. Chen Y. Ma B. Wang Y. In vitro and in vivo evaluation of inhibition activity of lotus ( Nelumbo nucifera Gaertn.) leaves against ultraviolet B-induced phototoxicity J. Photochem. Photobiol. B Biol. 2013 121 1 5 10.1016/j.jphotobiol.2013.02.005 23474526
30. Liu S. Li D. Huang B. Chen Y. Lu X. Wang Y. Inhibition of pancreatic lipase, α-glucosidase, α-amylase, and hypolipidemic effects of the total flavonoids from Nelumbo nucifera leaves J. Ethnopharmacol. 2013 149 263 269 10.1016/j.jep.2013.06.034 23811214
31. Xiao J. Capanoglu E. Jassbi A.R. Miron A. Advance on the Flavonoid C-glycosides and Health Benefits Crit. Rev. Food Sci. Nutr. 2016 56 S29 S45 10.1080/10408398.2015.1067595 26462718
32. Chen S. Wu B.H. Fang J.B. Liu Y.L. Zhang H.H. Fang L.C. Guan L. Li S.H. Analysis of flavonoids from lotus ( Nelumbo nucifera ) leaves using high performance liquid chromatography/photodiode array detector tandem electrospray ionization mass spectrometry and an extraction method optimized by orthogonal design J. Chromatogr. A 2012 1227 145 153 10.1016/j.chroma.2011.12.098 22265782
33. Charbe N.B. McCarron P.A. Lane M.E. Tambuwala M.M. Application of three-dimensional printing for colon targeted drug delivery systems Int. J. Pharm. Investig. 2017 7 47 59 10.4103/jphi.JPHI 28929046
34. Li S.S. Wu J. Chen L.G. Du H. Xu Y.J. Wang L.J. Zhang H.J. Zheng X.C. Wang L.S. Biogenesis of C-glycosyl flavones and profiling of flavonoid glycosides in lotus ( Nelumbo nucifera ) PLoS ONE 2014 9 10.1371/journal.pone.0108860 25279809
35. Ahn J.H. Kim E.S. Lee C. Kim S. Cho S.H. Hwang B.Y. Lee M.K. Chemical constituents from Nelumbo nucifera leaves and their anti-obesity effects Bioorganic Med. Chem. Lett. 2013 23 3604 3608 10.1016/j.bmcl.2013.04.013 23642481
36. Wang H.M. Yang W.L. Yang S.C. Chen C.Y. Chemical constituents from the leaves of Nelumbo nucifera gaertn. cv. Rosa-plena Chem. Nat. Compd. 2011 47 316 318 10.1007/s10600-011-9919-z
37. Ohkoshi E. Miyazaki H. Shindo K. Watanabe H. Yoshida A. Yajima H. Constituents from the leaves of Nelumbo nucifera stimulate lipolysis in the white adipose tissue of mice Planta Med. 2007 73 1255 1259 10.1055/s-2007-990223 17893829
38. Kim H.K. Park H.R. Lee J.S. Chung T.S. Chung H.Y. Chung J. Down-regulation of iNOS and TNF-α expression by kaempferol via NF-κB inactivation in aged rat gingival tissues Biogerontology 2007 8 399 408 10.1007/s10522-007-9083-9 17278014
39. Li F. Sun X.Y. Li X.W. Yang T. Qi L.W. Enrichment and separation of quercetin-3-O-β-D-glucuronide from lotus leaves ( nelumbo nucifera gaertn.) and evaluation of its anti-inflammatory effect J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 2017 1040 186 191 10.1016/j.jchromb.2016.12.017 27987489
40. You J.S. Lee Y.J. Kim K.S. Kim S.H. Chang K.J. Ethanol extract of lotus ( Nelumbo nucifera ) root exhibits an anti-adipogenic effect in human pre-adipocytes and anti-obesity and anti-oxidant effects in rats fed a high-fat diet Nutr. Res. 2014 34 258 267 10.1016/j.nutres.2014.01.003 24655493
41. Ho H.H. Hsu L.S. Chan K.C. Chen H.M. Wu C.H. Wang C.J. Extract from the leaf of nucifera reduced the development of atherosclerosis via inhibition of vascular smooth muscle cell proliferation and migration Food Chem. Toxicol. 2010 48 159 168 10.1016/j.fct.2009.09.033 19799955
42. Huang C.F. Chen Y.W. Yang C.Y. Lin H.Y. Way T. Der Chiang W. Liu S.H. Extract of lotus leaf ( Nelumbo nucifera ) and its active constituent catechin with insulin secretagogue activity J. Agric. Food Chem. 2011 59 1087 1094 10.1021/jf103382h 21235242
43. Yang M.Y. Chang Y.C. Chan K.C. Lee Y.J. Wang C.J. Flavonoid-enriched extracts from Nelumbo nucifera leaves inhibits proliferation of breast cancer in vitro and in vivo Eur. J. Integr. Med. 2011 3 10.1016/j.eujim.2011.08.008
45. Le Roy J. Huss B. Creach A. Hawkins S. Neutelings G. Glycosylation Is a Major Regulator of Phenylpropanoid Availability and Biological Activity in Plants Front. Plant Sci. 2016 7 10.3389/fpls.2016.00735 27303427
46. Ferreres F. Gil-Izquierdo A. Andrade P.B. Valentão P. Tomás-Barberán F.A. Characterization of C-glycosyl flavones O-glycosylated by liquid chromatography-tandem mass spectrometry J. Chromatogr. A 2007 1161 214 223 10.1016/j.chroma.2007.05.103 17602695
47. Drouet S. Garros L. Hano C. Tungmunnithum D. Renouard S. Hagège D. Maunit B. Lainé É. A Critical View of Different Botanical, Molecular, and Chemical Techniques Used in Authentication of Plant Materials for Cosmetic Applications Cosmetics 2018 5 30 10.3390/cosmetics5020030
48. Tungmunnithum D. Thongboonyou A. Pholboon A. Yangsabai A. Flavonoids and Other Phenolic Compounds from Medicinal Plants for Pharmaceutical and Medical Aspects: An Overview Medicines 2018 5 93 10.3390/medicines5030093 30149600
49. Chen H. Sun K. Yang Z. Guo X. Wei S. Identification of Antioxidant and Anti- α -amylase Components in Lotus ( Nelumbo nucifera , Gaertn.) Seed Epicarp Appl. Biochem. Biotechnol. 2018 1 14 10.1007/s12010-018-2844-x 30039473
50. Jiang X.L. Wang L. Wang E.J. Zhang G.L. Chen B. Wang M.K. Li F. Flavonoid glycosides and alkaloids from the embryos of Nelumbo nucifera seeds and their antioxidant activity Fitoterapia 2018 125 184 190 10.1016/j.fitote.2018.01.009 29371159
51. Wang M. Shi J. Wang L. Hu Y. Ye X. Liu D. Chen J. Inhibitory kinetics and mechanism of flavonoids from lotus ( Nelumbo nucifera Gaertn.) leaf against pancreatic α-amylase Int. J. Biol. Macromol. 2018 120 2589 2596 10.1016/j.ijbiomac.2018.09.035 30195612
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