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[미국특허] Hyaluronidase 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-037/54
출원번호 US-0829785 (1986-02-14)
우선권정보 GB-0004025 (1985-02-16)
발명자 / 주소
  • Sawyer Roy T. (Swansea GBX) Edwards Jeffrey (Swansea GBX)
출원인 / 주소
  • Biopharm (UK) Limited (Swansea GBX 03)
인용정보 피인용 횟수 : 38  인용 특허 : 1

초록

The hyaluronidase, which is a hyaluronic acid-specific endo-bHirudinaria manillensis or Poecilobdella granulosa). The hyaluronidase, which cleaves hyaluronic acid, but not chondroitin, chondroitin -4- sulphate, chondroitin -6- sulphate or heparin, is considerably more stable at high temperatures and

대표청구항

A hyaluronic acid-specific endo-b

이 특허에 인용된 특허 (1)

  1. Jacobson Bernard (Lexington MA) Raymond Laurie (Cambridge MA), Cell proliferation inhibitor and method of preparation.

이 특허를 인용한 특허 (38)

  1. Stern Robert ; Frost Gregory I. ; Hall Jackson ; Shuster Svetlana ; Formby Bent ; Colbern Gail T., BH55 hyaluronidase.
  2. Yatsuka, Nobuaki; Sato, Nobuyuki; Moriyama, Shigeru; Tamai, Tadakazu; Nishikawa, Masazumi, Compounds having glucuronic acid derivatives and glucosamine derivative in the structure, process for producing the same and utilization thereof.
  3. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Hyaluronidase and factor VIII compositions.
  4. Karageozian, Hampar L.; Karageozian, Vicken H.; Kenney, Maria Cristina; Gutierrez Flores, Jose Luis; Carpio Aragon, Gabriel Arturo; Nesburn, Anthony B., Hyaluronidase preparation for ophthalmic administration and enzymatic methods for accelerating clearance of hemorrhagic blood from the vireous body of the eye.
  5. Karageozian, Hampar L.; Karageozian, Vicken H.; Kenney, Maria Cristina; Gutierrez Flores, Jose Luis; Carpio Aragon, Gabriel Arturo; Nesburn, Anthony B., Hyaluronidase preparation for ophthalmic administration and enzymatic methods for accelerating clearance of hemorrhagic blood from the vitreous body of the eye.
  6. Karageozian Hampar L. ; Karageozian Vicken H. ; Kenney Maria Cristina ; Gutierrez Flores Jose Luis,MXX ; Carpio Aragon Gabriel Arturo,MXX ; Nesburn Anthony B., Method for accelerating clearance of hemorrhagic blood from the vitreous body with hyaluronidase.
  7. Karageozian Hampar L. ; Karageozian Vicken H. ; Kenney Maria Christina ; Gutierrez Flores Jose Luis,MXX ; Carpio Aragon Gabriel Arturo,MXX ; Nesburn Anthony B., Method for accelerating clearance of hemorrhagic blood from the vitreous humor with hyaluronidase.
  8. Soll, David B., Method for treating elevated intraocular pressure, including glaucoma.
  9. Matalon, Reuben, Methods and compositions for delivering enzymes and nucleic acid molecules to brain, bone and other tissues.
  10. Bookbinder, Louis; Kundu, Anirban; Frost, Gregory I., Methods for reducing intraocular pressure by administering a soluble hyaluronidase glycoprotein (sHASEGP).
  11. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Methods for treating a disease characterized by an excess of hyaluronan by administering a soluble hyaluronidase glycoprotein (sHASEGP).
  12. Bookbinder, Louis; Kundu, Anirban; Frost, Gregory I., Methods for treating edema by administering a Soluble Hyaluronidase Glycoprotein (sHASEGP).
  13. Pakola, Steve; De Smet, Marc, Pharmacological vitreolysis.
  14. Pakola, Steve; De Smet, Marc, Pharmacological vitreolysis.
  15. Pakola, Steve; De Smet, Marc, Pharmacological vitreolysis.
  16. Pakola, Steve; De Smet, Marc, Pharmacological vitreolysis.
  17. Pakola, Steve; De Smet, Marc, Pharmacological vitreolysis.
  18. Pakola, Steve; De Smet, Marc, Pharmacological vitreolysis.
  19. Pakola, Steve; De Smet, Marc, Pharmacological vitreolysis.
  20. Pakola, Steve; De Smet, Marc, Pharmacological vitreolysis.
  21. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
  22. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
  23. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
  24. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
  25. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
  26. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
  27. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
  28. Bookbinder, Louis; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
  29. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof.
  30. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof.
  31. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof.
  32. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof.
  33. Bookbinder, Louis H.; Kundu, Anirbau; Frost, Gregory I., Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof.
  34. Bookbinder, Louis; Kundu, Anirban; Frost, Gregory I., Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof.
  35. Karageozian, Vicken H.; Castillejos, David; Park, John, Treatment of ophthalmic disorders using urea.
  36. Schuler, Ed; Schuler, Christopher, Use of Streptomyces hyalurolyticus enzyme in ophthalmic treatments.
  37. Karageozian, Hampar; Karageozian, Vicken; Kenney, Maria C.; Flores, Jose L. G.; Aragon, Gabriel Arturo Carpio; Nesburn, Anthony B., Use of hyaluronidase in the manufacture of an ophthalmic preparation for liquefying vitreous humor in the treatment of eye disorders.
  38. Karageozian, Hampar; Karageozian, Vicken; Kenney, Maria C.; Flores, Jose L. G.; Aragon, Gabriel Arturo Carpio; Nesburn, Anthony B., Use of hyaluronidase in the manufacture of an ophthalmic preparation for liquefying vitreous humor in the treatment of eye disorders.
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