초록

소아 희귀 난치성 질환 관련 임상 및 중개 기반 연구 수행가능한 전문 인력을 양성을 기반으로 고급 인프라를 구성하고,다학제간 협력을 통한 우수한 연구 수행이 가능하도록 체계적으로 관리하는 연세 소아 희귀난치성질화 연구회를 조직하여 운영하며, 소아 희귀 난치성 전문 연구자 양성 프로그램을 개발 및 진행함.

(출처 : 요약서 3p)

Abstract ▼

□ Purpose& Contents
Development a program for cultivate pediatric experts who are able to conduct clinical and translational research on pediatric rare refractory disease based on training, and systematical management to perform research through multidisciplinary collaboration.
(1) Development

□ Purpose& Contents
Development a program for cultivate pediatric experts who are able to conduct clinical and translational research on pediatric rare refractory disease based on training, and systematical management to perform research through multidisciplinary collaboration.
(1) Development integrated diagnosis and treatment systems for children with rare refractory disease based on multi-disciplinary approach.
(2) Development a protocol and its clinical application to treat characteristics of pediatric patients and care givers' emotion, animal models that identify their potential as a treatment.

□ Results
1) It is possible to perform clinical research among multidisciplinary researchers by cultivating high-quality experts about pediatric rare disease.
2) It is possible to present a new theoretical background for disease treatments through enhanced understanding about mechanism of pediatricrare disease.
3) It is possible to find out the factors related to the development of disease in one’s infancy.

□ Expected Contribution
○ Construct multidisciplinary research model of clinical and basic medicine.
- The multidisciplinary research model contributes to the development of collaborative research in the field of clinicians and basic medicine.
○ Organization of the research system through systematic multidisciplinary research networking
- Multidisciplinary networking of researchers in each field that share common research goals will contribute to the promotion of prolonged multidisciplinary collaboration research
○ Sharing scientific and clinical knowledge
- Promoting research cooperation model by sharing the latest knowledge and clinical experiences of pediatric rare disease research

(출처 : SUMMARY 5p)

목차 Contents

• 표지 ... 1
• 제 출 문 ... 2
• 보고서 요약서 ... 3
• 국문 요약문 ... 4
• SUMMARY ... 5
• 목차 ... 6
• 1. 연구개발과제의 개요 ... 7
• 1-1. 연구개발 목적 ... 7
• 1-2. 연구개발의 필요성 ... 7
• 1-3. 연구개발 범위 ... 8
• 2. 국내외 기술개발 현황 ... 10
• 3. 연구수행 내용 및 결과 ... 11
• 1. 1차년도 ... 11
• 2. 2차년도 ... 31
• 3. 3차년도 ... 47
• 4. 목표달성도 및 관련분야 기여도 ... 63
• 4-1. 목표달성도 ... 63
• 4-2. 관련분야 기여도 ... 63
• 5. 연구결과의 활용계획 ... 64
• 6. 연구과정에서 수집한 해외과학기술정보 ... 65
• 7. 연구개발성과의 보안등급 ... 65
• 8. 국가과학기술종합정보시스템에 등록한 연구시설·장비 현황 ... 65
• 9. 연구개발과제 수행에 따른 연구실 등의 안전조치 이행실적 ... 65
• 10. 연구개발과제의 대표적 연구실적 ... 66
• 11. 기타사항 ... 66
• 12. 참고문헌 ... 66
• [별첨4] 실적 증빙자료 ... 67
• [별첨5] 기타 첨부서류 ... 81
• 끝페이지 ... 86