The purpose of this study is to determine the effect of Fructus Rubi to the phenylehrine (PE) induced contraction of isolated rat aorta. Contractile force was measured with force displacement transducer under 1.5g loading tension. Contractions evoked by PE 0.1 μM and KCl 65.4 mM were decreased signi...
The purpose of this study is to determine the effect of Fructus Rubi to the phenylehrine (PE) induced contraction of isolated rat aorta. Contractile force was measured with force displacement transducer under 1.5g loading tension. Contractions evoked by PE 0.1 μM and KCl 65.4 mM were decreased significantly by Fructus Rubi. L-NNA, ODQ, indomethacin and atropine significantly altered the effect of Fructus Rubi, but propranolol did not change the relaxation of Fructus Rubi. These results indicate that Fructus Rubi can relax EP and KCl induced contraction of isolated rat aorta and that this decreasing contraction related to epithelium, nitric oxide, and parasympathetics.
The purpose of this study is to determine the effect of Fructus Rubi to the phenylehrine (PE) induced contraction of isolated rat aorta. Contractile force was measured with force displacement transducer under 1.5g loading tension. Contractions evoked by PE 0.1 μM and KCl 65.4 mM were decreased significantly by Fructus Rubi. L-NNA, ODQ, indomethacin and atropine significantly altered the effect of Fructus Rubi, but propranolol did not change the relaxation of Fructus Rubi. These results indicate that Fructus Rubi can relax EP and KCl induced contraction of isolated rat aorta and that this decreasing contraction related to epithelium, nitric oxide, and parasympathetics.
Keyword
#복분자[覆盆子] 한약재[韓藥材] 복분자 물추출물 적출동맥 FRUCTUS RUBI WATER EXTRACT AORTA
학위논문 정보
저자
선성규
학위수여기관
圓光大學校
학위구분
국내박사
학과
한의학과
발행연도
2002
총페이지
22장
키워드
복분자[覆盆子] 한약재[韓藥材] 복분자 물추출물 적출동맥 FRUCTUS RUBI WATER EXTRACT AORTA
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