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고지방식을 섭취한 흰쥐의 체내 지질 함량에 대한 대두 단백질과 칼슘의 섭취 효과

Effects of Dietary Soy Protein and Calcium on Blood and Tissue Lipids in Rats Fed Fat-Enriched Diet


This study was carried out to examine how dietary protein and calcium levels in rats fed fat-enriched diet affect the total lipid and cholesterol contents of blood and tissues. Male Sprauge-Dawley rats weighing approximately 200g were fed six purified diets which contained 18%(w/w) beef tallow, 1% (w/w) cholesterol, two source of protein, casein or isolated soy protein (ISP) and three levels of dietary calcium, 0.1%, 0.4% and 1.0%, first, for four weeks, and second, for eight weeks. The contents of the total lipid, cholesterol and triglyceride in blood, liver, heart and feces were determined. After four weeks feeding serum lipid and cholesterol concentrations significantly decreased in rats fed 1.0% (w/w) level calcium, regardless of dietrary protein sources. After eight weeks, these concentrations were significantly lower in the rats fed soy protein than in casein-fed rats. As dietary calcium level increased serum and tissue lipid and cholesterol contents were decreased and fecal lipid excretion increased. It is concluded that hypolipidemic and/or hypocholesterolemic effects of soy protein and calcium were partly due to decrease in lipid absorption.

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이 논문을 인용한 문헌 (9)

  1. 1996. "Effect of the mixture of grain components on the Hematology and growth of Rat" 韓國資源植物學會誌 = Korean journal of plant resources, 9(1): 77~87 
  2. 1997. "A Study on the Bioavailability of Dietary Calcium Sources" 韓國營養學會誌 = The Korean journal of nutrition., 30(5): 499~505 
  3. 1997. "Effects of Protein Hydrolysates on Blood and Liver Lipids in Rats fed Fat-enriched Diet" 韓國營養學會誌 = The Korean journal of nutrition., 30(6): 614~621 
  4. 1998. "Effects of Yellow and Black Soybeans on Plasma and Hepatic Lipid Composition and Fecal Lipid Excretion in Rats" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 27(1): 126~131 
  5. 1998. "Effectso f Dehulled Defatted Soy Flour on Postprandial Lipid Profile and Enzyme and Hormone Levels in Rats" 韓國營養學會誌 = The Korean journal of nutrition., 31(2): 135~142 
  6. 2000. "Effects of Dehulled Defatted Soy Flour on Cholesterol Metabolism and Gastronitestinal Physiology in Rats" 韓國營養學會誌 = The Korean journal of nutrition., 33(4): 395~402 
  7. 2000. "Effects of Dietary Calcium and Sodium Levels on Lipid Metabolism in Hyperlipidemic/Hypercholesterolemic Rats" 韓國營養學會誌 = The Korean journal of nutrition., 33(4): 403~410 
  8. 2001. "Effects of Exercise and Calcium intake on Blood Pressure and Blood Lipids in Premenopausal Women" 韓國營養學會誌 = The Korean journal of nutrition., 34(1): 62~68 
  9. 2002. "Effect of Dietary Ca and Na Levels on Blood Pressure and Mineral Metabolism in Spontaneously Hypertensive Rats Fed High Fat Diet" 韓國營養學會誌 = The Korean journal of nutrition., 35(8): 840~847 


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