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[국내논문] Schisandra Chinensis Inhibits Oxidative DNA Damage and Lipid Peroxidation Via Antioxidant Activity 원문보기

韓國資源植物學會誌 = Korean journal of plant resources, v.22 no.3, 2009년, pp.195 - 202  

Jeong, Jin-Boo (School of Bioresources, Andong National University) ,  Jeong, Hyung-Jin (School of Bioresources, Andong National University)

Abstract ▼ AI-Helper 아이콘AI-Helper

Schisandra chinensis have been traditionally used in Asia for the treatment of dyspnea, cough, mouth dryness, spontaneous diaphoresis, nocturnal diaphoresis, nocturnal emission, dysentery, insomnia and amnesia. The purpose of this study is to evaluate the protective effects of Schisandra chinensis o...

Keyword

#Lipid peroxidation   #Oxidative DNA damage   #Oxidative cell death   #Reactive oxygen species (ROS)   #Schisandra chinensis  

AI 본문요약
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제안 방법

  • Also, the evaluation of its inhibitory effects on oxidative DNA and cell damages is necessary for the medicinal use of it as the cancer chemopreventive agent. In this study, we evaluated antioxidant and inhibitory effect of oxidative DNA damage and lipid peroxidation. Major questions we wish to address in our study are: (1) What is the effect of Schisandra Chinensis on DPPH radical, hydroxyl radical and hydrogen peroxide?, (2) Can Schisandra Chinensis affect lipid peroxidation in a cellular system?, and (3) What is the effect of Schisandra Chinensis on oxidative DNA damage induced by hydroxyl radical?
  • The series of experiments were performed as three or more independent examination with at least three replicates for each sample. Data were expressed as means ±S.

데이터처리

  • Data were expressed as means ±S.D. Statistical comparison was performed using Student’s t-test.

이론/모형

  • Hydrogen peroxide scavenging ability was measured according to a literature procedure (Pick and Keisari, 1989). One hundred micro liter of 0.
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