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NTIS 바로가기대한지역사회영양학회지 = Korean journal of community nutrition, v.15 no.6, 2010년, pp.796 - 805
This study investigated the correlations and risk distribution differences between high sensitivity C-reactive protein (hs-CRP) and the diagnosis factors of metabolic syndrome among the residents of a rural community. Two thousand adults aged from 40 to 70 were recruited and 1,968 subjects were incl...
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핵심어 | 질문 | 논문에서 추출한 답변 |
---|---|---|
대사증후군의 중요 병인은? | 이러한 군집현상을 ‘X 증후군’ 또는 ‘인슐린 저항성 증후군’이라(Reaven 1998) 하였고, 1998년 세계보건기구는 대사 증후군으로 명명하였다. 또한, 대사증후군은 대사증후군의 인자들인 고혈압, 당 대사이상들이 군집현상으로 복합적인 작용(Grundy 등 2005)이 중요 병인으로, 심혈관질환과 제2형 당뇨병의 발생을 증가시키는 것으로(McNeill 등 2005) 알려져 있다. 대사증후군 유병률은 미국에서는 34. | |
C-반응성 단백질은 어떤 상태에서 현저히 증가하는가? | C-반응성 단백질(C-reactive protein; CRP)은 간에서 생성되는 급성기 반응물질로 interlukin-6의 자극에 의해서 형성되며, 염증상태를 평가하는데 이용되고 있 다(Ridker 등 2001). 또한 염증성 질환, 체내 조직의 괴사와 같은 질환에서 현저하게 증가하며, 각종 염증 반응 및 질병의 활성도를 측정하는 지표로 이용되어 왔다. 심혈관 질환이나 비만, 인슐린저항성과 연관 되어있고(Albert 2000), 고감도 C-반응성 단백질(high sensitivity Creactive protein; hs-CRP)은 높은 정밀도로 낮은 범위의 CRP도 측정할 수 있게 되어 미약한 염증 발생도 알 수 있으며, 심혈관질환, 당뇨병 발생의 예측인자로(Roberts 2004) 활용할 수 있다. | |
대사증후군은 어떻게 나타나는가? | 대사증후군(metabolic syndrome)은 인슐린 저항성과 고 인슐린혈증으로 인한 당대사 이상, 고혈압, 복부비만 등과 같은 대사 이상들이 군집적으로 나타나 한 개인에게 흔 하게 나타난다는 사실이 수 십년 전부터 인지 되어 왔다. 이러한 군집현상을 ‘X 증후군’ 또는 ‘인슐린 저항성 증후군’이라(Reaven 1998) 하였고, 1998년 세계보건기구는 대사 증후군으로 명명하였다. |
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