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大韓化粧品學會誌 = Journal of the society of cosmetic scientists of Korea, v.37 no.1, 2011년, pp.1 - 21
조완구 (전주대학교 대체의학대학 기초의과학과)
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This review describes several kinds of emulsification methods for nanoemulsions and the application of nanoemulsions. Nanoemulsion droplet sizes fall typically in the range of 20 ~200 nm and show narrow size distributions. Although most of the publications on either oil-in-water (O/W) or water-in-oi...
| 핵심어 | 질문 | 논문에서 추출한 답변 |
|---|---|---|
| 나노에멀젼은 마이크로에멀젼과 달리 어떤 특징을 가지는가? | 나노에멀젼은 입자가 50 ∼ 200 nm의 크기를 가지며 열역학적으로 안정한 마이크로에멀젼과는 달리 운동학적으로만 안정하다[1,2]. 그러나 나노에멀젼은 마크로에멀젼과는 달리 입자들 사이의 응집 현상이나 합일현상이 없기 때문에 낮은 점도 조건에서도 장기간 안정하다[3.4]. | |
| 생활용품이나 화장품 분야에서 나노에멀젼이 유용한 제형으로 사용되는 것에 대한 이유는 무엇이 있는가? | 생활용품이나 화장품 분야에서 나노에멀젼이 유용한 제형으로 사용되는 것은 이유는 다음과 같다. 첫째, 나노에멀젼은 입자가 매우 작아, 입자의 브라운 운동으로 중력의 영향을 받지 않아 침전 또는 크리밍 현상에 자유롭다. 둘째, 작은 입자로 응집 현상이 없어 에멀젼이 분리될 가능성이 낮다. 셋째, 작은 입자는 입자의 변형이 적어 합일을 방지할 수 있다. 더욱이 입자의 반경에 비해 두꺼운 계면 막은 입체적 안정화에 기여한다. 넷째, 작은 입자로 넓은 계면 막을 보유하여 유효성분의 피부 침투를 개선할 수 있다. 다섯째, 투명하고 낮은 점도로 피부에 청량감을 줄 수 있으며 여섯째, 마이크로에멀젼에 비해 현격하게 적은 계면활성제로 제조가 가능하며, 피부 표면에 균일한 도포가 가능하다. 이상과 같은 다양한 장점에도 불구하고 나노에멀젼은 고압 유화기와 같은 특별한 제조기기가 필요하고 안정성 기작에 대한 이해도가 떨어지는 등 단점을 가지고 있다. | |
| 나노에멀젼은 실용적인 측면에서 어느 분야에서 연구되고 있는가? | 4]. 나노에멀젼은 입자 크기의 특성 때문에 육안으로 Figure 1과 같이 투명 또는 반투명으로 보이며 따라서 나노에멀젼은 기본적으로 과학적인 흥미를 유발할 뿐만 아니라 실용적인 측면에서도 화장품, 의약품, 화학분야에서 다양하게 연구되고 있다[5-14]. O/W 타입 나노에멀젼은 오래전부터 연구되어 왔으며 많은 연구자들이 검토하였다[6-12]. |
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