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NTIS 바로가기KJWHN : Korean journal of women health nursing, v.21 no.2, 2015년, pp.106 - 114
김윤미 (가천대학교 간호대학) , 안숙희 (충남대학교 간호대학)
Purpose: The purpose of this review was to describe a psychoneuroimmunology (PNI) framework for postpartum depression (PPD) and discuss its implications for nursing research and practice for postpartum women. Methods: This study explored the role of hypothalamic-pituitary-adrenal (HPA) axis and infl...
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핵심어 | 질문 | 논문에서 추출한 답변 |
---|---|---|
산후 우울이란 무엇인가요? | 산후 우울은 산욕기 산모에게 가장 흔히 발생하는 정신건강 문제이다. 산후 우울의 발생률은 나라에 따라, 도구에 따라 또는 측정시기에 따라 그 정도가 다르지만 최저 11%에서 최고 42. | |
시상하부-뇌하수체-부신 축(HPA축)은 어디에 광범위한 영향을 미치나요? | 시상하부-뇌하수체-부신 축(HPA축)은 면역, 대사 및 생식 과정에 광범위한 영향을 미친다. 신체에 급성 스트레스가 발생하면 HPA축은 생체리듬에 따라 분비하는 코티졸 양보다 훨씬 많은 양을 분비하여 혈중 글루코코르티코이드를 증가시키고, 이는 단시일적으로 염증촉진 사이토카인(cytokine)을 억제함으로써 면역력 강화 효과를 나타낸다[12]. | |
연구자들이 산후 HPA 재조직 또는 불응기가 PPD의 병태생리에서 중요한 역할을 한다고 제안한 이유는 무엇인가요? | 이러한 HPA축의 기능 저하는 태반 만출과 함께 임신이 종료되어도 출산 후 HPA축의 조절 장애가 지속되고[8], 임신 전 역동적인 균형상태로 HPA축의 기능이 회복되는데 최소 2~3개월이 소요된다고 예측한다[20]. 따라서 연구자들은 산후 HPA 기능의 재조직 또는 불응기가 바로 PPD의 병태생리에서 중요한 역할을 한다고 제안한다[8,20,21]. |
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