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계지복령환(桂枝茯苓丸)의 배오(配伍)분석과 그 생리활성
Analysis for Compatibility of Gyejibongnyeong-hwan and Its Biological Activities 원문보기

大韓韓醫學方劑學會誌 = Herbal formula science, v.24 no.4, 2016년, pp.353 - 365  

김도회 (동의대학교 한의과대학 방제학교실 및 한방당뇨비만연구소) ,  정양삼 (정양삼한의원) ,  윤미정 (목원대학교 의생명.보건학부) ,  윤유식 (중앙대학교 의과대학 미생물학교실) ,  신순식 (동의대학교 한의과대학 방제학교실 및 한방당뇨비만연구소)

Abstract AI-Helper 아이콘AI-Helper

Objectives : We analysed Gyejibongnyeong-hwan's compatibility principle and investigated biological activities by categorizing with molecular level, cellular level, animal level and human level based on Korean study for this formula. Methods : Gyejibongnyeong-hwan's compatibiltity principle was exam...

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AI-Helper 아이콘 AI-Helper

문제 정의

  • 본 연구에서는 桂枝茯苓丸의 配伍원리를 분석하고, 우리나라에서 발표된 논문을 중심으로 분자수준, 세포 수준, 동물수준 및 인간수준으로 구분하여 桂枝茯苓丸의 생리활성을 살펴보고자 한다.
본문요약 정보가 도움이 되었나요?

질의응답

핵심어 질문 논문에서 추출한 답변
桂枝茯苓丸이란?  桂枝茯苓丸은 活血化瘀와 緩消癥塊의 작용을 가진 方劑이다.『金匱要略』의「婦人妊娠病脈證幷治」에서 처음으로 수재되었고, “婦人宿有癥病, 經斷未及三月, 而得漏下不止, 胎動在臍上者, 爲癥痼害.
桂枝는 어떤 작용이 있나? 李飛는 “桂枝는 性味가 辛甘溫하고 通血脈의 작용 이 있어서 經血을 잘 흐르게하고, 三焦를 引導하고 아 래로는 膀胱을 通하여 소변을 순조롭게 보는 작용이 있다. 본 방제에 사용되어 通血脈하고 消瘀血하며 氣 化작용을 돕고 津液을 行하게 하여 약물 하나로 두 가 지 작용을 하게 한다.
桂枝茯苓丸은 어디에 처음으로 수재되었나?  桂枝茯苓丸은 活血化瘀와 緩消癥塊의 작용을 가진 方劑이다.『金匱要略』의「婦人妊娠病脈證幷治」에서 처음으로 수재되었고, “婦人宿有癥病, 經斷未及三月, 而得漏下不止, 胎動在臍上者, 爲癥痼害.” 1)의 癥塊를 전문적으로 치료하는 方劑이다.
질의응답 정보가 도움이 되었나요?

참고문헌 (43)

  1. Chen Ji Fan. "Synopsis of the Golden Chamber". 1st edition. Beijing: People's Medical Publishing House, 2000: 655-658. 

  2. Gong Ting Xian. "Curative Measures for All Diseases". Li Shi Hua, Wang Yu Xue. "Gong Ting Xian Medical Book". 1st edition. Beijing: China Press of Traditional Chinese Medicine, 1999: 397. 

  3. Chen Zi Ming. "Complete Effective Prescriptions for Women". Sheng Wei Zhong. "Chen Zi Ming Medical Book". 1st edition. Beijing: China Press of Traditional Chinese Medicine, 2005: 137. 

  4. Heo Jun author; the literature research institute of eastern medicine translation; Jin Jupyo notes. "New translation of Treasured Mirror of Eastern Medicine". revised edition. Seoul: BUBIN PUBLISHERS CO., 2009: 1666-1667. 

  5. Kim Do Hoy, Seo Bu-il, Kim Bo Kyung, Kim Gyeong Cheol, Shin Soon Shik. Standard Principles for the Designing of Prescriptions - The Theory for Monarch, Minister, Adjuvant and Dispatcher. The Korean Journal of Oriental Medical Prescription. 2003; 11(2): 1-18. 

  6. https://oasis.kiom.re.kr 

  7. Liu Xue Wen, Tang Qing Xiang. "Formula Solutions and Taste Memory". 1st edition. Shenyang:Liaoning Science and Technology Publishing House, 1999:191. 

  8. Xie Ming. "Formula Science". 1st edition. Beijing:People's Medical Publishing House, 2002:429-430. 

  9. Li Fei. "Formula Science"(Volume 2). 2nd edition. Beijing: People's Medical Publishing House, 2011:1256. 

  10. Ni Cheng. "New Edited Formula Science". 1st edition. Beijing: People's Medical Publishing House, 2006: 558. 

  11. Li Qing Ye, Yang Bin. "Illustrated Formula Science". 1st edition. Beijing: People's Medical Publishing House, 2004: 166. 

  12. Zhang Min Qing. "Modern Clinical Formula Science". 1st edition. Beijing: People's Medical Publishing House, 2004: 542. 

  13. Yi In-Ho, Cho Jung-Hoon, Jang Jun-Bock, Lee Kyung-Sub. A Study on the inhibitory effect of Gaejibokryungwhan on the growth of Human Uterine Myomal Cells. The Journal of Oriental Obstetrics & Gynecology. 2002; 15(2): 12-24. 

  14. Hong Yun-Pyo, Ro Sung-Hyun. Effects of geagibokrounghwan(桂枝茯?丸) on superoxide dismutase gene expression in experimental mouse fed cholesterol. THE KOREAN JOURNAL OF ORIENTAL MEDICAL PRESCRIPTION. 1998;6(1): 215-226. 

  15. Hwang Deok-Sang, Cho Jung-Hoon, Jang Jun-Bock, Lee Kyung-Sub. Inhibitory Effects of Gaejibokryunghwan on Cell Proliferation in HeLa Cells. Journal of Korean Oriental Medicine. 2006; 27(1): 23-35. 

  16. Jung Hoon, Lee Eun-Jung, Oh Min-Seok. The Effects of Gyejibokryeong-hwan for Wound Healing after Skin Suture. Journal of Korean Medicine Rehabilitation. 2016; 26(2): 29-50. 

  17. Kim Jin-hee, Baek Sung-hee. A study on inhibitory effects of Gaejiboknyunghwan on growth of uterine myoma cell and activity of MAP kinase. The Journal of Oriental Obstetrics & Gynecology. 2001; 14(2): 85-101. 

  18. Kim Yun-gun, Park Chang-gun, Kim Dong-chul, Baek Seung-hee. A study on inhibitory effects of Gaejiboknyunghwan on growth of uterine cancer cell and activity of MAP kinase. The Journal of Oriental Obstetrics & Gynecology. 2002; 15(1): 31-43. 

  19. Soo Kyung Lee, Han Geu Kim, Jong Chan Ahn, Tae Wook Chung, Jin Young Moon, Sun Dong Park, June Ki Kim, Dall Yeong Choi, Cherl Ho Kim, Won Hwan Park. Effect of the Geijibokryunghwan on human hepatocarcinoma cells. Korean Journal of Oriental Physiology & Pathology. 2003; 17(2): 568-573. 

  20. Kwon Young-Ku, Ahn Young-Min, Ahn Se-Young, Doo Ho-Kyung. The Experimental Studies Of The Kaejibokryungwhan, Sobokchugeotang, And Dohongsamultang On The Mesangial Cell Proliferation And Fibronectin Synthesis. Korean Journal of Oriental Internal Medicine. 2003;24(1): 94-103. 

  21. Han Geu Kim, Jong Gu Kim, Seog Ha Kim, Eun-Ho Sa, Jae-Woo Kim, Jin Young Moon, Sun Dong Park, Dall Yeong Choi, Cherl Ho Kim, Won Hwan Park. Influence of Geijibokryunghwan on Platelet Aggregation, Cyclic AMP, Cyclic GMP, TXA2, $Ca^{2+}$ Mobilization, Tyrosine Phosphorylation of PLC- ${\gamma}$ 2 and IP3 in Activated Platelets. Korean Journal of Oriental Physiology & Pathology. 2004; 18(6): 1860-1868. 

  22. Shin Jin Sik, Ahn Kyou Suk, Moon Joon Jeon. Studies on the Effect of Kejibockryung-Hwan against Liver Damage in $CCl_4$ induced Albino-Rat. THE KYUNG HEE UNIVERSITY ORIENTAL MEDICAL JOURNAL. 1981; 4: 161-170. 

  23. Lee Pil Rae, Ahn Gyoo Seock, Choi Seung Hoon. Study on the Effects of Guizhifulingwan(桂枝茯?丸) and Its Components on Dextran-Induced Blood Stasis and HA-Induced Elevated Blood Viscosity Models. THE KYUNG HEE UNIVERSITY ORIENTAL MEDICAL JOURNAL. 1996; 19(2): 39-67. 

  24. Moon Jong-mo, Kim Sung Hoon. Effects of Kyejibokryounghwan, Jeodangtang, Kyejibokryounghwan & Jeodangtang on Intravascular Coagulation Induced by Endotoxin in Rats. THESIS COLLECTION RESEARCH INSTITUTE OF KOREAN MEDICINE. 1996; 4(2): 91-103. 

  25. Yi In-Ho, Lee Kyung-Sub, Song Byoung-Key. Effects of Guizibokryungwhan Aqua-acupuncture on the Intravascular Coagulation Induced by Endotoxin in Rats. THE JOURNAL OF ORIENTAL GYNECOLOGY. 2000; 13(1): 1-17. 

  26. Kim Jong-Gu, Kim Chang-Hwan, Park Soo- Young, Kim Jong-Soo, Choi Jae-Yun, Kim Cheul-Ho, Park Won-Hwan. An Experimental Study on the Effect of Geijibokryunghwan, Dangguijakyaksan and Each Constituent Herb on Inhibition of Platelet Aggregation. The Journal Of The Korea Institute Of Oriental Medical Diagnostics. 2000; 4(2): 71-84. 

  27. Kim Jong-Goo, Park Sun-Dong, Park Won- Hwan. Effect of Geijibokryunghwan and each constituent herb on inhibition of platelet aggregation. The Journal of Dong Guk Oriental Medicine. 2000; 8(2): 115-129. 

  28. Ha Dong Ju, Jeong Kyung Jin, Lee Ki Nam. Effect of Kaejibokryungwhan on Analgesic, Anti-Inflammation, Anti-Convulsion, Muscle Relaxation and Changes of Body Temperature through Experimental Animals. THE JOURNAL OF KOREAN ORIENTAL MEDICAL SOCIETY. 1995; 16(1): 339-350. 

  29. Lee Seung-Hun, Park Sun-Dong, Park Won-Hwan. Antioxidant effects of Geagibokrounghwan(桂枝茯?丸) in experimental mouse fed cholesterol. The Journal of Dong Guk Oriental Medicine. 1999; 8(1): 35-49. 

  30. Kang Sol, Nam Seok Won, Jo Han Baek, Kim Jong Hwan, Kim Cheol Won, Yoo Sim Geun. Case Reports of Gyejibongnyeonghwangami for Ovarian cyst. THE JOURNAL OF ORIENTAL GYNECOLOGY. 2000; 13(2): 399-406. 

  31. Paik Jin-Won, Han Sung-Ho, Eum Hyung-Sup, Kim Jae-Woo, Jeong Sung-Hyun, Shin Gil-Cho, Lee Won-Chul. One Case of Menorrhalgia Treated by Oriental Medicine. The Korean Journal of Joongpoong. 2003; 4(1): 93-99. 

  32. Choi Ga-Ya, Cho Jung-Hoon, Jang Jun-Bock, Lee Kyung-Sub. Clinical Study on the Efficacy of Gyejibongnyeong-hwan in the Treatment of Menorrhalgia. The Journal of Oriental Obstetrics & Gynecology. 2004; 17(1): 178-186. 

  33. Nam Eun Jung, Lee Yeon Kyeong, Lee Dong Nyung, Kim Hyung Jun. Clinical Study on the Effect of Gyebongnyeong capsule in the Treatment of Primary Dysmenorrhea. Korean Journal of Oriental Physiology & Pathology. 2006; 20(5): 1364-1368. 

  34. Cho Jung-Hoon. A Pilot Study of the Difference between Gyejibongnyeong-hwan and Gyejibongnyeonghwan combined Acupuncture Therapy on the Primary Dysmenorrhea. The Journal of Oriental Obstetrics & Gynecology. 2007; 20(1): 161-168. 

  35. Jeong-Su Park, Sunju Park, Chun-Hoo Cheon, Ho-Yeon Go, Seung-Ho Sun, Yong-Cheol Shin, Bo-Hyoung Jang and Seong-Gyu Ko. Effects of Gyejibongnyeong-hwan on dysmenorrhea caused by blood stagnation: study protocol for a randomized controlled trial. Trials 2012, 13:3. 

  36. Jeong-Su Park, Sunju Park, Chun-Hoo Cheon, Seong-Cheon Jo, Han Baek Cho, Eun-Mee Lim, Hyung Ho Lim, Bo-Hyoung Jang, Yong-Cheol Shin, and Seong-Gyu Ko. Effects and Safety of Gyejibongnyeong-Hwan on Dysmenorrhea Caused by Blood Stagnation: A Randomized Controlled Trial. Evidence-Based Complementary and Alternative Medicine. 2013;2013:1-6. 

  37. Park Jea-Min, Yang Jeong-Min, Kim Dong-Il. A Clinical Trial to Verity the Quality of Life Improvement Efficacy of Dangguijakyak-san and Gyejibongnyeong-hwan Granulation in Postmenopausal Woman. The Journal of Oriental Obstetrics & Gynecology. 2007; 20(3): 213-228. 

  38. Jo Hee-Guen, Park Ae-RYEON, Kee Young- Bum, Kang Dae-HEE, Choi Jin-Bong, Sul Jae-Uk. A Clinical Trial on the Blood Stasis and Efficacy of Kyejibokryong-whan(Guizhifuling-wan) in the Patients with Motor Vehicle Accident. Journal of Oriental Rehabilitation Medicine. 2011; 21(3): 45-55. 

  39. Gao Xue Min, Zhong Gong Sheng. "Science of Chinese Materia Mmedica "(Volume 1). 2nd edition. Beijing: People's Medical Publishing House, 2015: 182, 408, 729. 

  40. Gao Xue Min, Zhong Gong Sheng. "Science of Chinese Materia Mmedica "(Volume 2). 2nd edition. Beijing: People's Medical Publishing House, 2015: 1108, 1626, 1746. 

  41. "The Korean Pharmacopoeia" Monographs part II. 11th Edition. Cheongju: MINISTRY OF FOOD AND DRUG SAFETY, 2016. 

  42. "The Korean Herbal Pharmacopoeia". Cheongju: MINISTRY OF FOOD AND DRUG SAFETY, 2016. 

  43. National Pharmacopoeia Commission. "Pharmacopoeia of The People's Republic of China"(volume 1). 2015 edition. Beijing: China Medical Science and Technology Publishing House, 2015: 105, 172, 240-241, 276-278. 

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