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NTIS 바로가기Journal of Korean biological nursing science, v.18 no.3, 2016년, pp.135 - 143
김재희 (연세대학교 대학원 간호학과.세브란스 심장혈관병원) , 추상희 (연세대학교 임상간호과학과.김모임 간호학연구소)
Purpose: This study was conducted to identify the factors associated with obstructive sleep apnea (OSA) risk in patients with metabolic syndrome (MS). Methods: Patients with MS between 30 and 74 years of age were recruited in an outpatient clinic of a cardiovascular center in Seoul, South Korea. MS ...
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핵심어 | 질문 | 논문에서 추출한 답변 |
---|---|---|
OSA가 대사증후군에서 흔히 관찰되는 이유는 무엇인가? | 대사증후군은 고혈압, 이상지혈증, 공복혈당 장애, 복부비만이 한 사람에게 복합적으로 나타나는 현상으로 심혈관질환의 대표적인 위험인자로 알려져 있다. 대사증후군에서 OSA가 흔히 관찰되는 이유는 반복적인 무호흡과 각성이 혈압, 인슐린 저항성, 콜레스테롤을 높이고, 비만을 촉진시키기 때문이다. 수면 중 기도가 막히게 되면 대사활동을 보존하기 위해 심박동수는 느려지고 혈관은 수축하게 된다. | |
OSA의 국내 유병률은 어떠한가? | OSA의 국내 유병률은 남성 4.5%, 여성 3.2%로 보고되었으나, 본인이 지각하지 못하는 경우를 감안하면 실제로는 중년 인구의 20.0-30.0%가 될 것으로 추정되고 있으며[4], 대사증후군환자의 경우 OSA의 유병률은 50.0-60.0%로 높아지는 것으로 알려져 있다[5]. 대사증후군은 고혈압, 이상지혈증, 공복혈당 장애, 복부비만이 한 사람에게 복합적으로 나타나는 현상으로 심혈관질환의 대표적인 위험인자로 알려져 있다. | |
폐쇄성수면무호흡증은 어떤 증상을 유발하는가? | 폐쇄성수면무호흡증(obstructive sleep apnea, OSA)은 수면 중 반복적으로 상기도를 폐쇄시켜 일시적인 무호흡 및 저호흡을 일으키고 이로 인해 혈중 산소농도가 낮아지게 된다. 무호흡이 나타날 때마다 뇌에서는 호흡을 회복하기 위해 각성이 일어나게 되며 밤 동안의 잦은 각성은 수면분열을 초래하여 낮에 졸림증, 피로, 집중력 저하, 두통, 인지기능저하 등 다양한 문제를 일으킨다. 또한 반복적인 ‘수면-각성 주기’는 3, 4단계의 깊은 수면과 렘수면으로의 이행을 방해하여 수면의 질을 떨어뜨리고 이는 낮 시간 동안 운전이나 작업 중 사고 위험성을 증가시킨다[1,2]. 그러나 OSA의 가장 큰 문제는 고혈압, 심근경색증, 부정맥, 심부전, 뇌졸중 등 심혈관질환의 위험을 높여 사망률까지 영향을 미칠 수 있다는 것이다. OSA와 심혈관질환의 관계를 체계적 문헌고찰 한 최근 연구에서는 OSA환자에서 고혈압이 발생할 위험성이 2. |
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