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NTIS 바로가기Journal of applied biological chemistry, v.60 no.4, 2017년, pp.321 - 326
김민주 (Department of Food Science and Technology, Seoul National University of Science and Technology) , 김민서 (Department of Food Science and Technology, Seoul National University of Science and Technology) , 강성태 (Department of Food Science and Technology, Seoul National University of Science and Technology) , 김지연 (Department of Food Science and Technology, Seoul National University of Science and Technology)
We aimed to assess the potential growth-promoting effects of ginger and cinnamon mixtures (GCM) on intestinal bacteria and their anti-inflammatory effects in a cellular model of intestinal inflammation. Bifidobacterium longum, Lactobacillus sp., and Lactobacillus acidophilus served as intestinal bac...
핵심어 | 질문 | 논문에서 추출한 답변 |
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생강은 무엇인가? | 생강(Ginger)은 생강과(Zingiber officinale Roscoe)에 속하는 다년생 초본식물로 특유의 매운맛과 방향성 향기를 지니고 있어 전 세계적으로 널리 애용되고 있으며, 우리나라에서도 식품과 음료 등에 많이 사용되고 있는 향신료 중의 하나이다(Kim과 Ahn 1993; Sung 2010). 생강추출물에 관한 연구로 Yang등(1992)이 생강추출물의 항위염·항궤양 작용을 입증하였고,생강의 항균성에 관하여 식중독 세균에 대한 증식저해작용 연구(Kim 등, 2000) 및 천연 생강 추출물의 약리학적 특성 및 분석 연구(Sung 2010) 등이 보고되고 있고, 이들의 약리효과에 대한 성분들이 밝혀지면서 기능성식품으로의 이용도가 높아지고있다(Han 2012). | |
인류가 이용한 가장 오래된 항신료 중의 하나인 계피는 어떤 약리효능을 갖는 가? | 계피(Cinnamomum japonicum SIEB)는 녹나무과(Lauraceae)에 속하고 Cinnamomum속인 열대성 상록수의 외피를 제거하여 건조하거나 껍질을 그대로 건조시킨 것이며, 인류가 이용한 가장 오래된 항신료 중의 하나이다. 계피의 약리효능으로는 항균작용 및 항궤양효과(Jeong 등, 1998), 항산화작용(Park과 Park 2000), 항알레르기 효과(Park 등, 2001), B형간염 바이러스 억제 효과(Kang 등, 1999) 등이 보고된 바 있다. | |
장내 세균총들은 어떤 역할을 하는 가? | 인체의 장내에 존재하는 100조의 세균들은 섭취된 음식물과 소화관으로부터 분리되는 생체성분을 이용하여 증식하고 분변으로 배출된다(Park 등, 2010). 장내 세균총들은 장관 내에 증식함으로서 상호공생관계에 의해 세균총의 균형을 정상적으로 유지하거나 길항 관계에 의하여 유해 미생물의 증식을 억제하고 있다(Fuller 1992). 장내 미생물들 이외에 장세포들 또한 염증과 관련된 유전자의 발현을 조절하는 다양한 세포 내 신호전달경로의 활성화를 통해 여러 염증 신호에 반응한다(Beatrice 등, 2009; Romier-Crouzet 등, 2009; Wullaert 등, 2011; Olejnik등, 2016). |
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