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NTIS 바로가기韓國藥用作物學會誌 = Korean journal of medicinal crop science, v.25 no.1, 2017년, pp.22 - 28
엄지나 ((주)지에프씨) , 민진우 ((주)지에프씨) , 주광식 ((주)지에프씨) , 강희철 ((주)지에프씨)
Background: To date, the anti-wrinkle efficacy of phellodendri cortex has not been defined. In this study, we investigated the nitric oxide (NO) production and elastase inhibitory activities of 80% methanol extract of Phellodendri cortex and its ethyl acetate fraction. Methods and Results: We prepar...
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핵심어 | 질문 | 논문에서 추출한 답변 |
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황백은 무엇인가? | 황백 (Phellodendron amurense Ruprecht)은 운향과 (Rutaceae)에 속하는 낙엽활엽교목인 황백나무 껍질을 벗긴 수피를 말려 약용으로 사용하는 것으로서, 우리나라 전 지역을 비롯한 중국, 일본에 분포하여 자생되고 있다 (Lee, 1993). 황백은 신라 시대에 처음으로 사용된 것으로 보고되어 있으며 한국의 전통 한약재로서 해독, 해열, 황달, 설사, 요도관 및 피부 감염증, 무릎과 발의 통증에 폭넓게 사용되어 왔다. | |
한약재로 황백의 효능은? | 황백 (Phellodendron amurense Ruprecht)은 운향과 (Rutaceae)에 속하는 낙엽활엽교목인 황백나무 껍질을 벗긴 수피를 말려 약용으로 사용하는 것으로서, 우리나라 전 지역을 비롯한 중국, 일본에 분포하여 자생되고 있다 (Lee, 1993). 황백은 신라 시대에 처음으로 사용된 것으로 보고되어 있으며 한국의 전통 한약재로서 해독, 해열, 황달, 설사, 요도관 및 피부 감염증, 무릎과 발의 통증에 폭넓게 사용되어 왔다. 또한 여러 연구에 의해 황백나무의 피부 melanin 생합성 저해 활성 (Lee et al. | |
황백의 약리성분은? | , 2003)이 보고되었으며, 구강균 (Kwak, 2004)에 대한 저해 효과가 확인된 바 있다. 약리 성분으로 berberine, palmatine, jatrorrhizine, phellodendrine, menisperine, candicine, magnoflorine 등 여러 종류의 alkaloid를 함유하고 있으며 대표적인 주성분은 berberine으로 이와 같은 유효성분들의 분리에 대한 연구는 여러 차례 이루어진 바 있다 (Kim et al., 2013a, b). |
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