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Molecular Signature That Determines the Acute Tolerance of G Protein-Coupled Receptors 원문보기

Biomolecules & therapeutics, v.25 no.3, 2017년, pp.239 - 248  

Min, Chengchun (Pharmacology Laboratory, College of Pharmacy, Chonnam National University) ,  Zhang, Xiaohan (Pharmacology Laboratory, College of Pharmacy, Chonnam National University) ,  Zheng, Mei (Pharmacology Laboratory, College of Pharmacy, Chonnam National University) ,  Sun, Ningning (Pharmacology Laboratory, College of Pharmacy, Chonnam National University) ,  Acharya, Srijan (Pharmacology Laboratory, College of Pharmacy, Chonnam National University) ,  Zhang, Xiaowei (Pharmacology Laboratory, College of Pharmacy, Chonnam National University) ,  Kim, Kyeong-Man (Pharmacology Laboratory, College of Pharmacy, Chonnam National University)

Abstract AI-Helper 아이콘AI-Helper

Desensitization and acute tolerance are terms used to describe the attenuation of receptor responsiveness by prolonged or intermittent exposure to an agonist. Unlike desensitization of G protein-coupled receptors (GPCRs), which is commonly explained by steric hindrance caused by the ${\beta}$

주제어

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