$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Abstract AI-Helper 아이콘AI-Helper

The intestinal microbiota has increasingly been shown to have a vital role in various aspects of human health. Among the vast gut bacterial community, Bifidobacterium is a genus which dominates the intestine of healthy breast-fed infants whereas in adulthood the levels are lower but relatively stabl...

주제어

AI 본문요약
AI-Helper 아이콘 AI-Helper

* AI 자동 식별 결과로 적합하지 않은 문장이 있을 수 있으니, 이용에 유의하시기 바랍니다.

문제 정의

  • 게다가, 비피도박테리아는 단쇄지방산, CLA(conjugated linoleic acid), 그리고 박테리오신을 포함하는 다양한 건강증진 대사물질 생산과 관련되어 있다. 본 고에서는 비피도박테리아와 연령 및 질병과 관련한 다양한 연구를 소개하고자 한다.
본문요약 정보가 도움이 되었나요?

질의응답

핵심어 질문 논문에서 추출한 답변
비피도박테리아란 무엇인가? 비피도박테리아는 Actinobacteria 문에 속하는 장관계의 정상적 미생물이다. 통성 혐기성 미생물에 의해 산소가 소진된 후에 비피도박테리아는 건강한 유아 장내에서 가장 풍부한 균종이다(Favier et al.
장내 미생물 다양성은 연령에 따라서 어떻게 변화하는가? , 2012). 미생물 다양성은연령에 따라 감소되나, Bacteroidetes와 Firmicutes는 우세함을 유지하고 몇몇 다른 종류가 상대적으로 풍부해지는데, 대부분 Proteobacteria(Biagi et al., 2012; Odamaki et al., 2016)이다.
성년기 및 노년기의 비피도박테리아 증감은? , 2002). 성년기 동안 상당히 감소되나, 상대적으로 안정적으로 유지되었다가 노년기에 다시 감소(Odamaki et al., 2016; Fig.
질의응답 정보가 도움이 되었나요?

참고문헌 (93)

  1. Akay, H. K., Bahar Tokman, H., Hatipoglu, N., Hatipoglu, H., Siraneci, R., Demirci, M., Borsa, B. A., Yuksel, P., Karakullukcu, A., Kangaba, A. A., Sirekbasan, S., Aka, S., Mamal Torun, M. and Kocazeybek, B. S. 2014. The relationship between bifidobacteria and allergic asthma and/or allergic dermatitis: a prospective study of 0-3 years-old children in Turkey. Anaerobe 28:98-103. 

  2. Arboleya, S., Binetti, A., Salazar, N., Fernandez, N., Solis, G., Hernandez- Barranco, A., Margolles, A., de Los Reyes-Gavilan, C. G. and Gueimonde, M. 2012. Establishment and development of intestinal microbiota in preterm neonates. FEMS Microbiol. Ecol. 79: 763-772. 

  3. Arboleya, S., Sanchez, B., Milani, C., Duranti, S., Solis, G., Fernandez, N., de los Reyes-Gavilan, C. G., Ventura, M., Margolles, A. and Gueimonde, M. 2015. Intestinal microbiota development in preterm neonates and effect of perinatal antibiotics. J. Pediatr. 166:538-544. 

  4. Arboleya, S., Watkins, C., Stanton, C. and Ross, R. P. 2016. Gut bifidobacteria populations in human health and aging. Frontiers in Microbiology 7:1-9. 

  5. Barrett, E., Kerr, C., Murphy, K., O'Sullivan, O., Ryan, C. A., Dempsey, E. M., Murphy, B. P., O'Toole P. W., Cotter, P. D., Fitzgerald, G. F., Ross, R. P. and Stanton, C. 2013. The individual-specific and diverse nature of the preterm infant microbiota. Arch. Dis. Child. Fetal Neonatal Ed. 98:F334-F340. 

  6. Bartosch, S., Fite, A., Macfarlane, G. T. and McMurdo, M. E. T. 2004. Characterization of bacterial communities in feces from healthy elderly volunteers and hospitalized elderly patients by using real-time PCR and effects of antibiotic treatment on the fecal microbiota. Appl. Environ. Microbiol. 70:3575-3581. 

  7. Bercik, P., Park, A. J., Sinclair, D., Khoshdel, A., Lu, J., Huang, X., Deng, Y., Blennerhassett, P. A., Fahnestock, M., Moine, D., Berger, B., Huizinga, J. D. Kunze, W., McLean, P. G., Begonzelli, G. E., Collins, S. M. and Verdu, E. F. 2011. The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication. Neurogastroenterol. Motil. 23:1132-1139. 

  8. Biagi, E., Candela, M., Fairweather-Tait, S., Franceschi, C. and Brigidi, P. 2012. Ageing of the human metaorganism: the microbial counterpart. Age. 34:247-267. 

  9. Biagi, E., Nylund, L., Candela, M., Ostan, R., Bucci, L., Pini, E., Nikkila, J., Monti, D., Satokari, R., Franceschi, C., Brigidi, P. and De Vos, W. 2010. Through ageing and beyond: Gut microbiota and inflammatory status in seniors and centenarians. PLoS ONE 5:e10667. 

  10. Biavatti, B. and Mattarelli, P. 2006. "The family Bifidobacteriaceae", in The Prokaryotes, 3rd Edn, Vol. 3, eds S. Falkow, E. Rosenberg, K. H. Schleifir, E. Stackebrandt and M. Dworkin (NewYork, NY: Springer- VerlagGmbH), pp. 322-382. 

  11. Chaplin, A. V., Brzhozovskii, A. G., Parfenova, T. V., Kafarskaia, L. I., Volodin, N. N., Shkoporov, A. N., Ilina, E. N. and Efimov, B. A. 2015. Species diversity of bifidobacteria in the intestinal microbiota studied using MALDI-TOF mass-spectrometry. Vestn. Ross. Akad. Med. Nauk 4:435-440. 

  12. Claesson, M. J., Jeffery, I. B., Conde, S., Power, S. E., O'Connor, E. M., Cusack, S., Harris, H. M., Coakley, M., Lakshminarayanan, B., O'Sullivan, O., Fitzgerald, G. F., Deane, J., O'Connor, M., Harnedy, N., O'Connor, K., O'Mahony, D., van Sinderen, D., Wallace, M., Brennan L., Stanton, C., Marchesi, J. R., Fitzgerald, A. P., Shanahan, F., Hill, C., Ross, R. P. and O'Toole, P. W. 2012. Gut microbiota composition correlates with diet and health in the elderly. Nature 488:178-184. 

  13. Clarke, G., Stilling, R. M., Kennedy, P. J., Stanton, C., Cryan, J. F. and Dinan, T. G. 2014. Minireview: gutmicrobiota: the neglected endocrineorgan. Mol. Endocrinol. 28:221-1238. 

  14. Collado, M. C., Donat, E., Ribes-Koninckx, C., Calabuig, M. and Sanz, Y. 2008a. Imbalances in faecal and duodenal Bifidobacterium species composition in active and non-active coeliac disease. BMC Microbiol. 8:232. 

  15. Collado, M. C., Isolauri, E., Laitinen, K. and Salminen, S. 2008b. Distinct composition of gut microbiota during pregnancy in overweight and normal-weight women. Am. J. Clin. Nutr. 88:894-899. 

  16. Collado, M. C., Rautava, S., Aakko, J., Isolauri, E. and Salminen, S. 2016. Human gut colonisation may be initiated in utero by distinct microbial communities in the placenta and amniotic fluid. Sci. Rep. 6:23129. 

  17. Cronin, M., Morrissey, D., Rajendran, S., ElMashad, S. M., van Sinderen, D., O'Sullivan, G. C. and Tangney, M. 2010. Orally administered bifidobacteria as vehicles for delivery of agents to systemic tumors. Mol. Ther. 18:1397-1407. 

  18. Di Gioia, D., Aloisio, I., Mazzola, G. and Biavati, B. 2014. Bifidobacteria: their impact on gut microbiota composition and their applications as probiotics in infants. Appl. Microbiol. Biotechnol. 98:563-577. 

  19. Dominguez-Bello, M. G., Costello, E. K., Contreras, M., Magris, M., Hidalgo, G., Fierer, N. and Knight, R. 2010. Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns. Proc. Natl. Acad. Sci. U.S.A. 107:11971-11975. 

  20. Drago, L., Toscano, M., Rodighiero, V., De Vecchi, E. and Mogna, G. 2012. Cultivable and pyrosequenced fecal microflora in centenarians and young subjects. J. Clin. Gastroenterol. 46(Suppl.):S81-S84. 

  21. Duytschaever, G., Huys, G., Bekaert, M., Boulanger, L., De Boeck, K. and Vandamme, P. 2013. Dysbiosis of Bifidobacteria and Clostridium cluster XIVa in the cystic fibrosis fecal microbiota. J. Cyst. Fibros. 12:206-215. 

  22. Faa, G., Gerosa, C., Fanni, D., Nemolato, S., van Eyken, P. and Fanos, V. 2013. Factors influencing the development of a personal tailored microbiota in the neonate, with particular emphasis on antibiotic therapy. J. Matern. Fetal Neonatal Med. 26(Suppl. 2):35-43. 

  23. Favier, C. F., Vaughan, E. E., De Vos, W. M. and Akkermans, A. D. 2002. Molecular monitoring of succession of bacterial communities in human neonates. Appl. Environ. Microbiol. 68:219-226. 

  24. Gao, X., Jia, R., Xie, L., Kuang, L., Feng, L. and Wan, C. 2015. Obesity in school-aged children and its correlation with gut E. coli and Bifidobacteria: A casecontrol study. BMC Pediatr. 15:64. 

  25. Garrido, D., Dallas, D. C. and Mills, D. A. 2013. Consumption of human milk glycoconjugates by infantassociated bifidobacteria: Mechanisms and implications. Microbiology 159(Pt 4):649-664. 

  26. Gavini, F., Cayuela, C., Antoine, J. -M., Lecoq, C., Lefebvre, B., Membre, J. - M., et al. 2001. Differences in the distribution of bifidobacterial and enterobacterial species in human faecal microflora of three different(children, adults, elderly) age groups. Microb. Ecol. Health Dis. 13:40-45. 

  27. Gronlund, M. M., Gueimonde, M., Laitinen, K., Kociubinski, G., Gronroos, T., Salminen, S. and Isolauri, E. 2007. Maternal breast-milk and intestinal bifidobacteria guide the compositional development of the Bifidobacterium microbiota in infants at risk of allergic disease. Clin. Exp. Allergy 37:1764-1772. 

  28. Grzeskowiak, L., Sales Teixeira, T. F., Bigonha, S. M., Lobo, G., Salminen, S. and Ferreira, C. L. 2015. Gut Bifidobacterium microbiota in one-month-old Brazilian newborns. Anaerobe. 35(Pt B):54-58. 

  29. Guaraldi, F. and Salvatori, G. 2012. Effect of breast and formula feeding on gut microbiota shaping in newborns. Front. Cell. Infect. Microbiol. 2:94. 

  30. Guardamagna, O., Amaretti, A., Puddu, P. E., Raimondi, S., Abello, F., Cagliero, P. and Rossi, M. 2014. Bifidobacteria supplementation: effects on plasma lipid profiles in dyslipidemic children. Nutrition. 30, 831-836. 

  31. Guarner, F. and Malagelada, J. R. 2003. Gut flora in health and disease. Lancet. 361:512-519. 

  32. Gueimonde, M., Debor, L., Tolkko, S., Jokisalo, E. and Salminen, S. 2007. Quantitative assessment of faecal bifidobacterial populations by real-time PCR using lanthanide probes. J. Appl. Microbiol. 102:1116-1122. 

  33. Gueimonde, M., Ouwehand, A., Pitkala, K., Strandberg, T., Finne-Soveri, H. and Salminen, S. 2010. Fecal Bifidobacterium levels in elderly nursing home patients- Are levels as expected? Biosci. Microflora. 29:111-113. 

  34. Haarman, M. and Knol, J. 2005. Quantitative real-time PCR assays to identify and quantify fecal Bifidobacterium species in infants receiving a prebiotic infant formula. Appl. Environ. Microbiol. 71:2318-2324. 

  35. He, F., Ouwehand, A. C., Isolauri, E., Hosoda, M., Benno, Y. and Salminen, S. 2001. Differences in composition and mucosal adhesion of bifidobacteria isolated from healthy adults and healthy seniors. Curr. Microbiol. 43:351-354. 

  36. Hevia, A., Milani, C., Lopez, P., Donado, C. D., Cuervo, A., Gonzalez, S., Suarez, A., Turroni, F., Gueimonde, M., Ventura, M., Sanchez, B. and Margolles, A. 2016. Allergic patients with long-term asthma display low levels of Bifidobacterium adolescentis. PLoS ONE. 11:e0147809. 

  37. HMP. 2012. Structure, function and diversity of the healthy human microbiome. Nature 486:207-214. 

  38. Hopkins, M., Sharp, R. and Macfarlane, G. 2001. Age and disease related changes in intestinal bacterial populations assessed by cell culture, 16S rRNA abundance and community cellular fatty acid profiles. Gut. 48:198-205. 

  39. Hopkins, M. J. and Macfarlane, G. T. 2002. Changes in predominant bacterial populations in human faeces with age and with Clostridium difficile infection. J. Med. Microbiol. 51:448-454. 

  40. Jeffery, I. B., O'Toole, P. W., Ohman, L., Claesson, M. J., Deane, J., Quigley, E. M. and Simren, M. 2012. An irritable bowel syndrome subtype defined by speciesspecific alterations in faecal microbiota. Gut. 61:997-1006. 

  41. Kalliomaki, M., Collado, M. C., Salminen, S. and Isolauri, E. 2008. Early differences in fecal microbiota composition in children may predict overweight. Am. J. Clin. Nutr. 87:534-538. 

  42. Karlsson, F. H., Tremaroli, V., Nookaew, I., Bergstrom, G., Behre, C. J., Fagerberg, B., Nielsen, J. and Backhed, F. 2013. Gut metagenome in European women with normal, impaired and diabetic glucose control. Nature. 498:99-103. 

  43. Kerckhoffs, A. P., Samsom, M., vander Rest, M. E., de Vogel, J., Knol, J., Ben-Amor, K. and Akkermans, L. M. A. 2009. Lower Bifidobacteria counts in both duodenal mucosa- associated and fecal microbiota in irritable bowel syndrome patients. World J. Gastroenterol. 15:2887-2892. 

  44. Klaassens, E. S., Boesten, R. J., Haarman, M., Knol, J., Schuren, F. H., Vaughan, E. E. and de Vos, W. M. 2009. Mixed-species genomic microarray analysis of fecal samples reveals differential transcriptional responses of bifidobacteria in breast- and formula-fed infants. Appl. Environ. Microbiol. 7:2668-2676. 

  45. Koenig, J. E., Spor, A., Scalfone, N., Fricker, A. D., Stombaugh, J., Knight, R., Angenent, L. T. and Ley, R. E. 2011. Succession of microbial consortiain the developing infant gut microbiome. Proc. Natl. Acad. Sci. U.S.A. 108(Suppl. 1):4578-4585. 

  46. Lagier, J. C., Hugon, P., Khelaifia, S., Fournier, P. E., LaScola, B. and Raoult, D. 2015. The rebirth of culture in microbiology through the example of culturomics to study human gut microbiota. Clin. Microbiol. Rev. 28:237-264. 

  47. Lewis, Z. T., Totten, S. M., Smilowitz, J. T., Popovic, M., Parker, E., Lemay, D. G., et al. 2015. Maternal fucosyltransferase 2 status affects the gut bifidobacterial communities of breastfed infants. Microbiome 3:13. 

  48. Lyra, A., Rinttila, T., Nikkila, J., Krogius-Kurikka, L., Kajander, K., Malinen, Matto, J., Makela, L. and Palva, A. 2009. Diarrhoea-predominant irritable bowel syndrome distinguishable by 16S rRNA gene phylotype quantification. World J. Gastroenterol. 15:5936-5945. 

  49. Makino, H., Kushiro, A., Ishikawa, E., Kubota, H., Gawad, A., Sakai, T., Oishi, K., Martin, R., Ben-Amor, K., Knol, J. and Tanaks, R. 2013. Mother-to-infant transmission of intestinal bifidobacterial strains has an impact on the early development of vaginally delivered infant's microbiota. PLoS ONE 8:e78331. 

  50. Malaguarnera, G., Leggio, F., Vacante, M., Motta, M., Giordano, M., Bondi, A., Basile, F., Mastrojeni, S., Mistretta, A., Malaguarnera, M., Toscano, M. A. and Salmeri, M. 2012. Probiotics in the gastrointestinal diseases of the elderly. J. Nutr. Health Aging. 16:402-410. 

  51. Matsuki, T., Watanabe, K., Tanaka, R., Fukuda, M. and Oyaizu, H. 1999. Distribution of bifidobacterial species in human intestinal microflora examined with 16S rRNA-gene-targeted species-specific primers. Appl. Environ. Microbiol. 65:4506-4512. 

  52. Mayorga Reyes, L., Gonzalez Vazquez, R., Cruz Arroyo, S. M., Melendez Avalos, A., Reyes Castillo, P. A., Chavaro Perez, D. A., Ramos Terrones, I., Ramos Ibanez, N., Rodriguez Magallanes, M. M., Langella, P., Brmudez Humaran, L. and Azaola Espinosa, A. 2016. Correlation between diet and gut bacteria in a population of young adults. Int. J. Food Sci. Nutr. 67:470-478. 

  53. Mevissen-Verhage, E. A., Marcelis, J. H., de Vos, M. N., Harmsen-van Amerongen, W. C. and Verhoef, J. 1987. Bifidobacterium, Bacteroides and Clostridium spp. in fecal samples from breast-fed and bottle-fed infants with and without iron supplement. J. Clin. Microbiol. 25:285-289. 

  54. Mihajlovski, A., Dore, J., Levenez, F., Alric, M. and Brugere, J. -F. 2010. Molecular evaluation of the human gut methanogenic archaeal microbiota reveals an ageassociated increase of the diversity. Environ. Microbiol. Rep. 2:272-280. 

  55. Mikami, K., Takahashi, H., Kimura, M., Isozaki, M., Izuchi, K., Shibata, R., Sudo, N, Matsumoto H. and Koga, Y. 2009. Influence of maternal bifidobacteria on the establishment of bifidobacteria colonizing the gut in infants. Pediatr. Res. 65:669-674. 

  56. Million, M., Angelakis, E., Maraninchi, M., Henry, M., Giorgi, R., Valero, R., Vialettes, B. and Raoult, D. 2013. Correlation between body mass index and gut concentrations of Lactobacillus reuteri, Bifidobacterium animalis, Methanobrevibacter smithii and Escherichia coli. Int. J. Obes. (Lond.) 37:1460-1466. 

  57. Mitsuoka, T. 1992. Intestinal flora and aging. Nutr. Rev. 50:438-446. 

  58. Mitsuoka, T., Hayakawa, K. and Kimura, N. 1974. [The faecal flora of man. II. The composition of Bifidobacterium flora of different age groups]. Zentralbl. Bakteriol. Orig. A. 226:469-478. 

  59. Murphy, K., O'Shea, C. A., Ryan, C. A., Dempsey, E. M., O'Toole, P. W., Stanton, C. and Ross, R. P. 2015. The gut microbiota composition indichorionic triplet sets suggests a role for host genetic factors. PLoS ONE 10:e0122561. 

  60. Murri, M., Leiva, I., Gomez-Zumaquero, J. M., Tinahones, F. J., Cardona, F., Soriguer, F. and Queipo- Ortuno, M. I. 2013. Gut microbiota in children with type 1 diabetes differs from that in healthy children: a case-control study. BMC Med. 11:46. 

  61. Musilova, S., Rada, V., Vlkova, E. and Bunesova, V. 2014. Beneficial effects of human milk oligosaccharides on gut microbiota. Benef. Microbes 5:273-283. 

  62. Nakamura, T., Sasaki, T., Fujimori, M., Yazawa, K., Kano, Y., Amano, J. and Taniguchi, S. 2002. Cloned cytosine deaminase gene expression of Bifidobacterium longum and application to enzyme/pro-drug therapy of hypoxic solid tumors. Biosci. Biotechnol. Biochem. 66:2362-2366. 

  63. Odamaki, T., Kato, K., Sugahara, H., Hashikura, N., Takahashi, S., Xiao, J. Z. et al. 2016. Age-related changes in gut microbiota composition from newborn to centenarian: across-sectionalstudy. BMC Microbiol. 16:90. doi: 10.1186/s12866-016-0708-5 

  64. O'Sullivan, O., Coakley, M., Lakshminarayanan, B., Conde, S., Claesson, M. J., Cusack, S., Fitzgerald, A. P., O'Toole, P. W., Stanton, C., Ross, R. P. and ELDERMET Consortium. 2013. Alterations in intestinal microbiota of elderly Irish subjects post-antibiotic therapy. J. Antimicrob. Chemother. 68:214-221. 

  65. Palma, G. D., Capilla, A., Nova, E., Castillejo, G., Varea, V., Pozo, T., Garrote, J. A., Polanco, I., Lopez, A., Ribes- Koninckx, C., Marcos, A., Garcia-Novo, M. D., Calvo, C., Ortigosa, L., Pena-Quintana, L., Palau, F. and Sanz, Y. 2012. Influence of milk-feeding type and genetic risk of developing coeliac disease on intestinal microbiota of infants: the PROFICEL study. PLoS ONE 7:e30791. 

  66. Penders, J., Thijs, C., Vink, C., Stelma, F. F., Snijders, B., Kummeling, I., van den Brandt, P. A. and Stobberingh, E. E. 2006. Factors influencing the composition of the intestinal microbiota in early infancy. Pediatrics. 118:511-521. 

  67. Picard, C., Fioramonti, J., Francois, A., Robinson, T., Neant, F. and Matuchansky, C. 2005. Review article: bifidobacteria as probiotic agents-physiological effects and clinical benefits. Aliment. Pharmacol. Ther. 22: 495-512. 

  68. Putignani, L., Del Chierico, F., Petrucca, A., Vernocchi, P. and Dallapiccola, B. 2014. The human gut microbiota: a dynamic interplay with the host from birth to senescence settled during childhood. Pediatr. Res. 76:2-10. 

  69. Qin, J., Li, R., Raes, J., Arumugam, M., Burgdorf, K. S., Manichanh, C., Nielsen, T., Pons, N., Levenez, F., Yamada, T., Mende, D. R., Li, J., Xu, J., Li, S., Li, D., Cao, J., Wang, B., Liang, H., Zheng, H., Xie, Y., Tap, J., Lepage, P., Bertalan, M., Batto, J. M., Hansen, T., Le Paslier, D., Linneberg, A., Nielsen, H. B., Pelletier, E., Renault, P., Sicheritz-Ponten, T., Turner, K., Zhu, H., Yu, C., Li, S., Jian, M., Zhou, Y., Li, Y., Zhang, X., Li, S., Qin, N., Yang, H., Wang, J., Brunak, S., Dore, J., Guarner, F., Kristiansen, K., Pefersen, O., Parkhill, J., Weissenbach, J., MetaHIT Consortium, Bork, P., Ehrlich, S. D. and Wang, J. 2010. A human gut microbial gene catalogue established by metagenomic sequencing. Nature 464:59-65. 

  70. Rajilic-Stojanovic, M., Heilig, H. G., Molenaar, D., Kajander, K., Surakka, A., Smidt, H. and de Vos, W. M. 2009. Development and application of the human intestinal tract chip, a phylogenetic microarray: analysis of universally conserved phylotypes in the abundant microbiota of young and elderly adults. Environ. Microbiol. 11:1736-1751. 

  71. Roger, L. C., Costabile, A., Holland, D. T., Hoyles, L. and McCartney, A. L. 2010. Examination of faecal Bifidobacterium populations in breast-and formulafed infants during the first 18 months of life. Microbiology 156:3329-3341. 

  72. Rondanelli, M., Giacosa, A., Faliva, M. A., Perna, S., Allieri, F. and Castellazzi, A. M. 2015. Review on microbiota and effectiveness of probiotics use in older. World J. Clin. Cases 3:156-162. 

  73. Salazar, N., Lopez, P., Valdes, L., Margolles, A., Suarez, A., Patterson, A. M., Cuervo, A., de los Reyes-Gavilan, C. G., Ruas-Madiedo, P., Gonzalez, S. and Gueimonde, M. 2013. Microbial targets for the development of functional foods accordingly with nutritional and immune parameters altered in the elderly. J. Am. Coll. Nutr. 32:399-406. 

  74. Santacruz, A., Collado, M. C., Garcia-Valdes, L., Segura, M. T., Martin-Lagos, J. A., Anjos, T., Marti-Romero, M., Lopez, R. M., Florido, J., Campoy, C. and Sanz, Y. 2010. Gut microbiota composition is associated with body weight, weightgain and biochemical parameters in pregnant women. Br. J. Nutr. 104:83-92. 

  75. Savignac, H. M., Kiely, B., Dinan, T. G. and Cryan, J. F. 2014. Bifidobacteria exert strain-specific effects on stress-related behavior and physiology in BALB/c mice. Neurogastroenterol. Motil. 26:1615-1627. 

  76. Sela, D. A., Chapman, J., Adeuya, A., Kim, J. H., Chen, F., Whiteheadf, T. R. et al. 2008. The genome sequence of Bifidobacterium longum subsp. infantis reveals adaptations for milk utilization within the infant microbiome. Proc. Natl. Acad. Sci. U.S.A. 105:18964-18969. 

  77. Sivan, A., Corrales, L., Hubert, N., Williams, J. B., Aquino- Michaels, K., Earley, Z. M., Benyamin, F. W., Lei, Y. M., Jabri, B., Alegre, M. L., Chang, E. B. and Gajewski, T. F. 2015. Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy. Science. 350:1084-1089. 

  78. Stsepetova, J., Sepp, E., Julge, K., Vaughan, E., Mikelsaar, M. and deVos, W. M. 2007. Molecularly assessed shifts of Bifidobacterium ssp. and less diverse microbial communities are characteristic of 5-year-old allergic children. FEMS Immunol. Med. Microbiol. 51:260-269. 

  79. Taverniti, V. and Guglielmetti, S. 2014. Methodological issues in the study of intestinal microbiota in irritable bowel syndrome. World J. Gastroenterol. 20:8821-8836. 

  80. Tojo, R., Suarez, A., Clemente, M. G., delos Reyes- Gavilan, C. G., Margolles, A., Gueimonde, M. and Ruas- Madiedo, P. 2014. Intestinal microbiota in health and disease: role of bifidobacteria in gut homeostasis. World J. Gastroenterol. 20:15163-15176. 

  81. Turroni, F., Peano, C., Pass, D. A., Foroni, E., Severgnini, M., Claesson, M. J., Kerr, C., Hourihane, J., Murray, D., Fuligni, F., Gueimonde, M., Margolles, A., De Bellis, G., O'Toole, P. W., van Sinderen, D., Marchesi, J. R. and Ventura, M. 2012. Diversity of bifidobacteria within the infant gut microbiota. PLoS ONE 7:e36957. 

  82. Turnbaugh, P. J., Hamady, M., Yatsunenko, T., Cantarel, B. L., Duncan, A., Ley, R. E., Sogin, M. L., Jones, W. J., Roe, D. A., Affourtit, J. P., Egholm, M., Henrissat, B., Heath, A. C., Knight, R. and Gordon, J. I. 2009. A core gut microbiome in obese and lean twins. Nature 457:480-484. 

  83. Underwood, M. A., German, J. B., Lebrilla, C. B. and Mills, D. A. 2015. Bifidobacterium longum subspecies infantis: champion colonizer of the infant gut. Pediatr. Res. 77:229-235. 

  84. van Tongeren, S. P., Slaets, J. P., Harmsen, H. J. and Welling, G. W. 2005. Fecal microbiota composition and frailty. Appl. Environ. Microbiol. 71:6438-6442. 

  85. Voreades, N., Kozil, A. and Weir, T. 2014. Diet and the development of the human intestinal microbiome. Front. Microbiol. 5:494. 

  86. Wang, F., Huang, G., Cai, D., Li, D., Liang, X., Yu, T. Shen, P., Su, H., Liu, J., Gu, H., Zhao, M. and Li, Q. 2015. Qualitative and semiquantitative analysis of fecal Bifidobacterium species in centenarians living in Bama, Guangxi, China. Curr. Microbiol. 71:143-149. 

  87. Woodmansey, E. J. 2007. Intestinal bacteria and ageing. J. Appl. Microbiol. 102:1178-1186. 

  88. Woodmansey, E. J., McMurdo, M. E., Macfarlane, G. T. and Macfarlane, S. 2004. Comparison of compositions and metabolic activities of fecal microbiotas in young adults and in antibiotic-treated and non-antibiotictreated elderly subjects. Appl. Environ. Microbiol. 70:6113-6122. 

  89. Wu, G. D. and Lewis, J. D. 2013. Analysis of the human gut microbiome and association with disease. Clin. Gastroenterol. Hepatol. 11:774-777. 

  90. Wu, X., Ma, C., Han, L., Nawaz, M., Gao, F., Zhang, X., Yu, P., Zhao, C., Li, L., Zhou, A., Wang, J., Moore, J. E., Millar, B. C. and Xu, J. 2010. Molecular characterisation of the faecal microbiota in patients with type II diabetes. Curr. Microbiol. 61:69-78. 

  91. Xu, M., Wang, B., Fu, Y., Chen, Y., Yang, F., Lu, H., Chen, Y., Xu, J. and Li, L. 2012. Changes of fecal Bifidobacterium species in adult patients with hepatitis B virus-induced chronic liver disease. Microb. Ecol. 63:304-313. 

  92. Yatsunenko, T., Rey, F. E., Manary, M. J., Trehan, I., Dominguez-Bello, M. G., Contreras, M., Magris, M., Hidalgo, G., Baldassano, R. N., Anokhin, A. P., Heath, A. C., Warner, B., Reeder, J., Kuczynski, J., Caporaso, J. G., Lozupone, C. A., Lauber, C., Clemente, J. C., Knights, R. and Gordon, J. I. 2012. Human gut microbiome viewed across age and geography. Nature. 486:222-227. 

  93. Zhao, L., Qiao, X., Zhu, J., Zhang, X., Jiang, J., Hao, Y. and Ren, F. 2011. Correlations of fecal bacterial communities with age and living region for the elderly living in Bama, Guangxi, China. J. Microbiol. 49:186-192. 

저자의 다른 논문 :

LOADING...

관련 콘텐츠

오픈액세스(OA) 유형

GOLD

오픈액세스 학술지에 출판된 논문

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로