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NTIS 바로가기생약학회지, v.49 no.3, 2018년, pp.189 - 202
김현정 (목포대학교 약학대학) , 윤구 (목포대학교 약학대학) , 조영창 (전남대학교 약학대학) , 이익수 (전남대학교 약학대학) , 강복윤 (전남대학교 약학대학)
Hop cones (Humuli Strobili) are the female inflorescences of hop plants (Humulus lupulus L.) belonging to the family Cannabaceae. They have been used as herbal remedies to treat mood and sleep disturbances, and mainly to add as a bittering ingredient in brewing process. Considerable interests on pha...
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핵심어 | 질문 | 논문에서 추출한 답변 |
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홉 추출물은 어디에 사용되는가? | 1,2) 이 생약은 특유의 향취와 함께 거의 둥글거나 달걀형의 약간 찌그러진 솔방울 모양의 구과(毬果)의 형태를 지녔으며, 세부적으로는 얇은 막질의 여러 포엽(苞葉)이 겹쳐져 있는 형태로서 포엽의 아랫부분 에는 등색~등황색의 분비물을 가진 특유한 홉 선체(腺體)가관찰된다. 3) 현재 홉 추출물이 건위소화 또는 수면유도 및 수면유지를 목적으로 의약품에 배합되고 있으며, 대부분의 홉은 맥주 제조 시 특유의 풍미와 쓴맛을 위해 주원료로 배합되고 있다. 2,4) | |
홉은 무엇인가? | 홉(hop, Humulus lupulus L.)은 삼과(Cannabaceae)에 속하는 유럽 원산의 여러해살이 암수딴그루의 덩굴성식물로, 그 성숙한 암꽃이 주로 의약적, 산업적 용도로 이용되고 있으며, 생약명은 기원식물과 같은 이름의 홉(Humuli Strobilus) 또는 홀포(忽布)라 이른다. 1,2) 이 생약은 특유의 향취와 함께 거의 둥글거나 달걀형의 약간 찌그러진 솔방울 모양의 구과(毬果)의 형태를 지녔으며, 세부적으로는 얇은 막질의 여러 포엽(苞葉)이 겹쳐져 있는 형태로서 포엽의 아랫부분 에는 등색~등황색의 분비물을 가진 특유한 홉 선체(腺體)가관찰된다. | |
홉의 효능은 무엇인가? | 5,6) 마지막으로 비교적 최근에 이르러서 다양한 생물활성으로 연구자들의 이목을 끌고 있는prenylated flavonoid 및 그 유도체 성분이 있다. 특히, xanthohumol과 그 flavanone 이성질체인 isoxanthohumol 그리고 xanthohumol의 탈메틸화 flavanone 유도체인 6-prenylnaringenin 및 8-prenylnaringenin이 항암, 항산화, 항염증 및 식물성 에스트로겐(phytoestrogen) 활성을 나타냄이 보고되면서 큰 주목을 받고 있다(Fig. 1). |
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