[논문]프로바이오틱스의 구강질병 개선에 관한 연구 고찰

정성균

doi:10.14400/jdc.2019.17.6.315

프로바이오틱스의 구강질병 개선에 관한 연구 고찰
Studies on the Oral Disease Improvement Effects of Probiotics : A Review 원문보기

디지털융복합연구 = Journal of digital convergence, v.17 no.6, 2019년, pp.315 - 326

정성균 (신한대학교 보건과학대학 치위생학과)

초록
AI-Helper

본 연구는 프로바이오틱스의 특성과 관련 연구에 대한 종설이다. 프로바이오틱스는 면역질환 개선 효과, 유당불내증 완화 효과, 변비 및 설사 개선 효과, 항암 및 항종양 효과, 심혈관계 질환 예방 효과, 항당뇨 효과, 항산화 효과, 항균효과, 유용 대사산물의 생산 등의 기능성을 입증하였다. 구강 프로바이오틱스는 젖산을 생성하여 충치의 원인이 되는 뮤탄스균과 잇몸 질환을 일으키는 진지발리스균을 비롯한 유해균이 서식하기 어려운 환경을 만들어 구강 생태계 조성과 구취 제거에 효과적이라는 연구가 입증되었다. 그 결과 질환 완화는 물론 건강한 구강 밸런스를 관리하는 예방법으로 주목받고 있다. 일부 제한점에도 불구하고 현재 유용한 임상연구가 진행되고 있으며, 본 연구는 치아우식증과 치주염, 칸디다의 집락화 등 구강상태를 개선하기 위한 프로바이오틱스의 근거가 될 수 있을 것이다.

Abstract ▼ AI-Helper

This study is a review of research articles on the characteristics of probiotics. Probiotics are effective at ameliorating immune disease, alleviating glucose intolerance, and improving constipation and diarrhea. Furthermore, they have anticancer and antitumor effects, preventive effects against cardiovascular disease, antidiabetic effects, antioxidant effects, antibacterial effects, and they produce useful metabolites. It has been demonstrated that oral probiotics are effective in eliminating halitosis and forming a favorable oral ecosystem, by creating an environment that is not readily inhabited by harmful bacteria, such as Streptococcus mutans, which produces lactic acid and causes tooth decay, or Porphyromonas gingivalis, which causes gum disease.As a result, oral probiotics are being considered not only as therapeutics against diseases, but also as preventive agents for the maintenance of a healthy oral balance. In spite of some limitations, clinical trials are currently underway, and this study can provide evidence to support the use of probiotics to improve oral health conditions, including dental caries, periodontal disease, and Candida colonization.

주제어

표/그림 (2)

그림 Fig. 1. Schematic diagram illustrating potential or known mechanisms of the impact of probiotic bacteriaon the microbiota.
표 Table 1. Different types of probiotic microbial strains, and their usage.

AI 본문요약
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문제 정의

However, probiotics are not being widely used in the improvement of oral health despite many such results. In this study, we aimed to summarize the findings on the functions of probiotics in the improvement of human health, and to explore the potential benefit of probiotics in the prevention of oral disease.
This study is a review of research articles on the characteristics of probiotics. In Stage 1, we designed and planned research content related to the characteristics of probiotics, and in Stage 2 we performed a literature search.
albicans. This study was a double-blind randomized comparative clinical trial to assess the effects of probiotics on the prevalence of candidiasis. Probiotic cheese or placebo cheese was consumed for 16 weeks by 276 elderly individuals.

제안 방법

reuteri twice a day. The study then evaluated the oral Candida count and prevalence. After 12 weeks, it was observed that L.

성능/효과

The study then evaluated the oral Candida count and prevalence. After 12 weeks, it was observed that L. reuteri treatment significantly reduced the salivary Candida count to below 104 CFU/ml in the treated subjects compared to the placebo group.

참고문헌 (67)

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표제어: PCR

동의어: Packet Collision Rate

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용어 설명: PCR은 세균 특이성이 있는 primer를 이용하여 적은 수의 세균이 있을지라도 쉽게 검출할 수 있는 유용한 방법이며, 이를 이용하여 구강 내 치면세균막이나 타액에서 직접 세균을 검출할 수 있게 되었다[8].

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