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NTIS 바로가기Korean journal of clinical laboratory science : KJCLS = 대한임상검사과학회지, v.52 no.3, 2020년, pp.165 - 171
김형락 (성가롤로병원 진단검사의학과)
This study examined the relationship between chronic kidney disease (CKD) and the homeostasis model assessment of insulin resistance (HOMA-IR) and beta-cell function (HOMA-B) in non-diabetic Korean adults. This study included 4,380 adults aged 20 or older (50.32±16.14) using the 2015 Korea Na...
핵심어 | 질문 | 논문에서 추출한 답변 |
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만성신장질환이란 무엇인가? | 만성신장질환(chronic kidney disease, CKD)은 전 세계 인구의 약 10%에게 영향을 미치는 매우 중요한 공중보건 문제이며, CKD 환자의 가장 흔한 사망 원인은 심혈관질환(cardiovascular disease, CVD)에 의한 합병증이다[1, 2]. CKD의 위험인자로 연령의 증가, 고혈압, 비만, 이상지질혈증뿐만 아니라 대사증후군과 당뇨병과 같은 인슐린저항성질환이 있다[3]. | |
인슐린저항성의 증가는 무엇에 영향을 미치는가? | 인슐린 저항성은 지방과 근육조직들이 인슐린에 대해 효과적으로 반응하지 못하여 포도당 이용 능력이 저하되어 있는 상태로 인슐린저항성의 증가는 당뇨뿐만 아니라 비만, 고혈압, 이상지질혈증, CKD 및 CVD 등의 대사질환에 영향을 미치는 것으로 알려져 있다[4, 5]. 인슐린저항성질환에서 췌장의 베타세포기능은 매우 중요하다. | |
만성신장질환의 위험인자는 무엇인가? | 만성신장질환(chronic kidney disease, CKD)은 전 세계 인구의 약 10%에게 영향을 미치는 매우 중요한 공중보건 문제이며, CKD 환자의 가장 흔한 사망 원인은 심혈관질환(cardiovascular disease, CVD)에 의한 합병증이다[1, 2]. CKD의 위험인자로 연령의 증가, 고혈압, 비만, 이상지질혈증뿐만 아니라 대사증후군과 당뇨병과 같은 인슐린저항성질환이 있다[3]. |
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