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Streptozotocin으로 유도된 당뇨 랫드에서 황칠나무 잎 열수추출물의 항당뇨 효과
Anti-diabetic effects of aqueous extract of Dendropanax morbifera Lev. leaves in streptozotocin-induced diabetic Sprague-Dawley rats 원문보기

Korean journal of veterinary research = 대한수의학회지, v.61 no.4, 2021년, pp.38.1 - 38.8  

김민재 (경상국립대학교 보건대학원) ,  강예진 (경상국립대학교 보건대학원) ,  이동언 (인제대학교 부산백병원 마취통증의학교실) ,  김석 (경상국립대학교 수의과대학 및 동물의학연구소) ,  임세훈 (인제대학교 부산백병원 마취통증의학교실) ,  이후장 (경상국립대학교 보건대학원)

Abstract AI-Helper 아이콘AI-Helper

This study examined the anti-diabetic effects of aqueous extracts of Dendropanax morbifera leaves (DMWEs) in streptozotocin-induced diabetic Sprague-Dawley (SD) rats. Thirty male SD rats (body weight [BW], 250.4 ± 19.7 g) were divided into the following six groups: normal control rats (NC), d...

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참고문헌 (39)

  1. Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Unwin N, Colagiuri S, Guariguata L, Motala AA, Ogurtsova K, Shaw JE, Bright D, Williams R; IDF Diabetes Atlas Committee. Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9th edition. Diabetes Res Clin Pract 2019;157:107843. 

  2. Cho KS. Current status of non-communicable diseases in the Republic Korea. Public Health Wkly Rep 2021;14:166-177. 

  3. Kim BY, Won JC, Lee JH, Kim HS, Park JH, Ha KH, Won KC, Kim DJ, Park KS. Diabetes fact sheets in Korea, 2018: an appraisal of current status. Diabetes Metab J 2019;43:487-494. 

  4. Kang AN, Kang SY, Song MY, Park YK. Effects of Spagranii Rhizoma extract on high fat.high sucrose diet and streptozotocin administration-induced diabetic rats. J Korean Med Obes Res 2016;16:92-100. 

  5. Kerner W, Bruckel J; German Diabetes Association. Definition, classification and diagnosis of diabetes mellitus. Exp Clin Endocrinol Diabetes 2014;122:384-386. 

  6. Choi CS. Pathogenesis of insulin resistance. Korean J Med 2009;77:171-177. 

  7. Taylor R. Type 2 diabetes: etiology and reversibility. Diabetes Care 2013;36:1047-1055. 

  8. Ra JC, Bae JH, Park HG, Kang KS. Studies on a new alimentoherapy for diabetic patients. J Korean Soc Food Sci Nutr 2003;32:614-620. 

  9. Rhee SY. Monotherapy in type 2 diabetes mellitus patients 2017: a position statement of the Korean Diabetes Association. J Korean Diabetes 2018;19:15-22. 

  10. Grover JK, Vats V, Rathi SS. Anti-hyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. J Ethnopharmacol 2000;73:461-470. 

  11. Heo MG, Byun JH, Kim J, Choung SY. Treatment of Dendropanax morbifera leaves extract improves diabetic phenotype and inhibits diabetes induced retinal degeneration in db/db mice. J Funct Foods 2018;46:136-146. 

  12. Kotb El-Sayed MI, Al-Massarani S, El Gamal A, El-Shaibany A, Al-Mahbashi HM. Mechanism of antidiabetic effects of Plicosepalus Acaciae flower in streptozotocin-induced type 2 diabetic rats, as complementary and alternative therapy. BMC Complement Med Ther 2020;20:290. 

  13. Mahmood R, Kayani WK, Ahmed T, Malik F, Hussain S, Ashfaq M, Ali H, Rubnawaz S, Green BD, Calderwood D, Kenny O, Rivera GA, Mirza B, Rasheed F. Assessment of antidiabetic potential and phytochemical profiling of Rhazya stricta root extracts. BMC Complement Med Ther 2020;20:293. 

  14. Lee JY, Park TH, Park SH, Yang SA, Jhee KH. The antimicrobial activity of fermented extracts from Korean Dendropanax morbifera. J Life Sci 2019;29:29-36. 

  15. Bae KH, Kim JA, Choi YE. Induction and in vitro proliferation of adventitious roots in Dendropanax morbifera. J Plant Biotechnol 2009;36:163-169. 

  16. Kim HS, Kim TW, Kim DJ, Lee JS, Choe M. Effects of medicinal herb water extracts on expression of hepatic glucokinase, pyruvate dehydrogenase and acetyl-CoA carboxylase mRNA. Korean J Nutr 2013;46:119-125. 

  17. Ahn JC, Kim MY, Kim OT, Kim KS, Kim SH, Kim SH, Hwang B. Selection of the high yield capacity of Hwangchil lacquer and identification of aromatic components in essential oil of Dendropanax morbifera Lev. Korean J Medicinal Crop Sci 2002;10:126-131. 

  18. Mali KK, Dias RJ, Havaldar VD, Yadav SJ. Antidiabetic effect of garcinol on streptozotocin-induced diabetic rats. Indian J Pharm Sci 2017;79:463-468. 

  19. Kwon TO, Choi JW, Lee HS, Cho BO, Yin HH, Jang SI. Anti-diabetic effects of Mori folium extract on high-fat diet and streptozotocin-induced type II diabetes mellitus in mice. Korean J Herbol 2015;30:1-9. 

  20. Algandaby MM, Alghamdi HA, Ashour OM, Abdel-Naim AB, Ghareib SA, Abdel-Sattar EA, Hajar AS. Mechanisms of the antihyperglycemic activity of Retama raetam in streptozotocin-induced diabetic rats. Food Chem Toxicol 2010;48: 2448-2453. 

  21. Oh IH, Yoon SJ, Kim EJ. The burden of disease in Korea. J Korean Med Assoc 2011;54:646-652. 

  22. Jeong IK, Chung JH, Min YK, Lee MS, Lee MK, Kim KW, Chung YE, Park JY, Hong SK, Lee KU. Comparative study about the effects of acarbose and voglibose in type 2 diabetic patients. J Korean Diabetes Assoc 2002;26:134-145. 

  23. Chien SC, Tseng YH, Hsu WN, Chu FH, Chang ST, Kuo YH, Wang SY. Anti-inflammatory and anti-oxidative activities of polyacetylene from Dendropanax dentiger. Nat Prod Commun 2014;9:1589-1590. 

  24. Choi JH, Kim S. Antioxidant and antithrombotic properties of Dendropanax morbifera Leveille (Araliaceae) and its ferments produced by fermentation processing. J Food Biochem 2019;43:e13056. 

  25. Choo GS, Lim DP, Kim SM, Yoo ES, Kim SH, Kim CH, Woo JS, Kim HJ, Jung JY. Anti-inflammatory effects of Dendropanax morbifera in lipopolysaccharide-stimulated RAW264.7 macrophages and in an animal model of atopic dermatitis. Mol Med Rep 2019;19:2087-2096. 

  26. Hyun TK, Kim MO, Lee H, Kim Y, Kim E, Kim JS. Evaluation of anti-oxidant and anti-cancer properties of Dendropanax morbifera Leveille. Food Chem 2013;141:1947-1955. 

  27. Kim ES, Lee JS, Akram M, Kim KA, Shin YJ, Yu JH, Bae ON. Protective activity of Dendropanax morbifera against cisplatin-induced acute kidney injury. Kidney Blood Press Res 2015;40:1-12. 

  28. Moon HI. Antidiabetic effects of dendropanoxide from leaves of Dendropanax morbifera Leveille in normal and streptozotocin-induced diabetic rats. Hum Exp Toxicol 2011;30:870-875. 

  29. Yoon JS, Kim KS, Kim JS. The effect of the Dendropanax morbifera media on the STZ-induced diabetic mice. J Korean Health Fundam Med Sci 2010;3:34-39. 

  30. Park SY, Karthivashan G, Ko HM, Cho DY, Kim J, Cho DJ, Ganesan P, Su-Kim I, Choi DK. Aqueous extract of Dendropanax morbiferus leaves effectively alleviated neuroinflammation and behavioral impediments in MPTP-induced Parkinson's mouse model. Oxid Med Cell Longev 2018;2018:3175214. 

  31. An NY, Kim JE, Hwang D, Ryu HK. Anti-diabetic effects of aqueous and ethanol extract of Dendropanax morbifera Leveille in streptozotocin-induced diabetes model. J Nutr Health 2014;47:394-402. 

  32. Singh LS, Singh NS, Devi MA. Hypoglycaemic effect of Lagerstroemia speciosa in type 2 diabetic rats. J Med Plant Res 2014;8:899-902. 

  33. Kim JH, Bae D, Lee U, Heo HJ. Ameliorating effect of water extract from Dendropanax morbifera Lev. on memory dysfunction in streptozotocin-induced diabetic rats. Korean J Food Sci Technol 2016;48:275-283. 

  34. Sachan R, Kundu A, Dey P, Son JY, Kim KS, Lee DE, Kim HR, Park JH, Lee SH, Kim JH, Cao S, Lee BM, Kwak JH, Kim HS. Dendropanax morbifera protects against renal fibrosis in streptozotocin-induced diabetic rats. Antioxidants (Basel) 2020;9:84. 

  35. Kim HR, Chung HJ. Seasonal changes in chemical components of the leaves of Dendropanax morbifera Lev. J Korean Soc For Sci 1999;88:562-567. 

  36. Kim YJ, Hwang BD. Factors affecting glycated hemoglobin (HbA1c) checkup of diabetic patients by gender: Using the community health survey. Korean J Health Educ Promot 2019;36:63-74. 

  37. Shin KH. Effects of Araliaceae water extracts on blood glucose level and biochemical parameters in diabetic rats. Korean J Nutr 2006;39:721-727. 

  38. Garcia-Compean D, Jaquez-Quintana JO, Gonzalez-Gonzalez JA, Maldonado-Garza H. Liver cirrhosis and diabetes: risk factors, pathophysiology, clinical implications and management. World J Gastroenterol 2009;15:280-288. 

  39. Kim HW, Ha TH, Cho MR, Cho SI. Effects of herbal remedy for diabetes mellitus-01 (HRDM-01) on liver and serum lipid level in diabetic rats. Korea J Herbol 2010;25:117-121. 

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