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논문 상세정보

소목(Caesalpinia sappan L.) 추출물의 피부 상재균에 대한 항균 활성

Antimicrobial activity of Caesalpinia sappan L. extract against skin flora

초록

소목(Caesalpinia sappan L.) 열수추출물의 피부상재균(Escherichia coli, Staphylococcus aureus, Cutibacterium acnes, Malassezia furfur)에 대한 항균 활성을 확인하였다. 소목 열수추출물의 수율과 폴리페놀 함량은 각각 14.01±0.81%과 487.5±19.69 ㎍/mg-추출물로 나타났다. 소목 열수추출물의 E. coli, S. aureus, C. acnes 및 M. furfur의 증식에 대한 최소저해농도는 각각 0.875, 1.750, 1.750 및 1.750 mg/mL이었다. 디스크 확산법에서 소목 열수추출물의 처리량에 비례하여 생육저해환이 증가하였다. 소목 열수추출물은 농도에 비례하여 피부상재균의 생육을 억제하였다.

Abstract

Antimicrobial activity of an aqueous extract from Caesalpinia sappan L. was investigated against skin flora such as Escherichia coli, Staphylococcus aureus, Cutibacterium acnes, and Malassezia furfur. The yield and polyphenol content of the aqueous extract were 14.01±0.81% and 487.5±19.69 ㎍/mg-extract, respectively. The minimum inhibitory concentration of the aqueous extract against E. coli, S. aureus, C. acnes, and M. furfur was 0.875, 1.750, 1.750, and 1.750 mg/mL, respectively. In disc diffusion test, the aqueous extract of C. sappan L. increased the clear zone in a dose-dependent manner. The aqueous extract inhibited the microbial growth in a concentration-dependent manner.

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