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복분자 종자 추출물의 항산화 및 항염증 효과
Antioxidant and anti-inflammatory effects of seed ethanol extracts of Rubus coreanus miquel 원문보기

Journal of plant biotechnology = 식물생명공학회지, v.49 no.2, 2022년, pp.155 - 161  

황진우 (단국대학교 보건복지대학 임상병리학과) ,  강현 (단국대학교 보건복지대학 임상병리학과) ,  이성규 (단국대학교 보건복지대학 임상병리학과)

초록
AI-Helper 아이콘AI-Helper

본 연구는 복분자 종자 에탄올 추출물의 항산화 및 항염증 활성 검증하였다. 항산화 활성을 알아보기 위하여 총 폴리페놀 및 플라보노이드 함량, ABTS 및 DPPH 라디칼 소거능과 환원력을 측정하였다. 복분자 종자 에탄올 추출물의 총 폴리페놀 및 플라보노이드 함량은 각각 4.09 ㎍ GAE/mg와 16.25 ㎍ QE/mg이었다. DPPH와 ABTS 라디칼 소거능은 농도 의존적 소거능을 보였고, 복분자 종자 에탄올 추출물의 RC50 값은 각각 26.68, 39.30 ㎍/mL이였다. 게다가 환원력을 평가하기 위해 수행된 FRAP 분석에서 복분자 종자 추출물은 0.61 ± 0.01 mM FeSO4 E/mg의 효능을 보여주었다. 항염증 효과를 측정하기 위해 RAW 264.7 세포에서 세포독성과 산화질소(NO) 생성 억제 효능을 확인하였다. 확인 결과 500 ㎍/mL의 복분자 종자 추출물에서 세포 독성 없이 산화질소 생성 억제 효능을 확인할 수 있었다. 복분자 종자 추출물을 사용한 항산화 및 항염증 활성을 확인한 결과 항산화 및 항염증 물질로서의 가능성을 확인할 수 있었다.

Abstract ▼ AI-Helper 아이콘AI-Helper

This study investigated the antioxidant and anti-inflammatory effects of seed ethanol extracts from Rubus coreanus Miquel (SERC). To investigate the antioxidant activity, total polyphenol and flavonoid content, ABTS and DPPH radical scavenging activity, and reducing power were measured. The total po...

주제어

#Seed of Rubus coreanus Miq   #   #Ethanol extracts   #Antioxidant   #Anti-inflammatory   #Cytotoxicity  

표/그림 (5)

참고문헌 (39)

  1. Awika JM, Rooney LW, Wu X, Prior RL, Cisneros-Zevallos L (2003). Screening methods to measure antioxidant activity of sorghum (Sorghum bicolor) and sorghum products. Journal of Agricultural and Food Chemistry. 51:6657-666 

    상세보기

  2. Benzie IF, Strain JJ (1996). The ferric reducing ability of plasma (FRAP) as a measure of antioxidant power the FRAP assay. Analytical Biochemistry. 239:70-76 

    상세보기

  3. Blois MS (1958). Antioxidant determinations by the use of a stable free radical. Nature. 181:1199-1200 

    상세보기

  4. Bogdan C (2015). Nitric oxide synthase in innate and adaptive immunity: an update. Trends in immunology. 36:161-178 

    상세보기

  5. Cha HS, Youn AR, Park PJ, Choi HR, Kim BS (2007). Comparison of physiological activities of Rubus coreanus Miquel during maturation. Journal of the Korean Society of Food Science and Nutrition. 36:683-688 

  6. Cho YJ, Chun SS, Kwon HJ, Kim JH, Yoon SJ, Lee KH (2005). Comparison of physiological activities between hotwater and ethanol extracts of Bokbunja (Rubus coreanum F.). Journal of the Korean Society of Food Science and Nutrition. 34:790-796 

  7. Choi JH, Ohk SH (2017). Evaluations on Antioxidant Effect of Water Extract from Graviola Leaves. J Korea AcademiaIndustrial cooperation Society. 18(6):129-135 

  8. Choi MR, Lee MY, Kim JE, Hong JE, Jang KH, Lee JY, Chun JW, Kim TH, Shin HK, Ki EJ (2012). Rubus coreanus Miquel Improves on Impairment of Memory in Senescence-Accelerated Mouse (SAM). Journal of the Korean Society of Food Science and Nutrition. 41(9):1253-1258 

  9. Duh PD, Du PC, Yen GC (1999). Action of methanolic extract of mung bean hulls as inhibitors of lipid peroxidation and non-lipid oxidative damage. Food and Chemical Toxicology. 37(11):1055-1061 

    상세보기

  10. Folin O, Denis W (1912). On phosphotungstic-phosphomolybdic compounds as color reagents. Journal of Biological Chemistry. 12(2):239-243 

    상세보기

  11. Hertog MGL, Hollman PCH, Van de Putte B (1993). Content of potentially anticarcinogenic flavonoids of tea infusions, wines and fruit juices. Journal of Agricultural and Food Chemistry. 41:1242-1246 

    상세보기

  12. Hertog MGL, Hollman PCH, Venema DP (1992). Optimization of a quantitative HPLC determination of potentially anticarcinogenic flavonoids in vegetables and fruits. Journal of Agricultural and Food Chemistry. 40:1591-159 

    상세보기

  13. Hwang JW, Choi JH, Kang SM, Lee SG, Kang H (2021). Antioxidant and Anti-inflammatory Effects of Hot Water and Ethanol Extracts from Endemic Plants in Indonesia. Biomedical Science Letters. 27:161-169 

    원문보기 상세보기

  14. Hwangbo H, Jeung JS, Kim MY, Ji SY, Yoon SH, Kim TH, Kim SO, Choi YH (2021). A Study on Antioxidant and Anti-inflammatory Effects Based on Analysis of Functional Components of Cornus officinalis Siebold & Zucc. Journal of Life Science. 31(3):287-297 

  15. Jang MJ, Seo SJ, Lee YS (2021). Antioxidant, Anti-inflammatory and Anti-aging Activities of Elaeagnus multiflora Fruit Extracts as a Cosmetic Material. Journal of Investigative Cosmetology. 17(2):159-167 

  16. Jeon HL, Kwak SM, Oh SJ, Nam HS, Han DW, Song YS, Song JW, Choi KC (2015). Blood Flow Improvement Effect of Bokbunja (Rubus coreanus) Seed Oil in High-Fat Diet-Fed Mouse Model. Journal of the Korean Society of Food Science and Nutrition. 44(8):1105-1113 

  17. Kang H, Lee SG (2021). Antioxidant Capacity of Ethanol Extracts and Fractions from Rubus coreanus Miq.. Journal of Plant Biotechnology. 48:264-270 

  18. Kim DH, Park JH, Kim JH, Kim CH, You JH, Kwon MC, Lee HY (2005). Enhancement of immune activities of Ephedrae Herba and Rubi Fructus at low temperature extraction. Korean Journal of Medicinal Crop Science. 13:81-86 

  19. Kim HM, Kim HJ, Kong CS, Lee BH, Sim HB, Seo YG (2021a). Antioxidant and Anti-inflammatory Activities of the Halophyte Cyrtomium falcatum. Ocean and Polar Research. 43(3):113-126 

  20. Kim ID, Kwon RH, Heo YY, Jung HJ, Kang HY, Ha BJ (2008). Supercritical extraction of Oriental herb: Anti-aging and anti-wrinkle effects. Korean Journal of Biotechnology and Bioengineering. 23:529-534 

  21. Kim JH, Kim CH, Kim HS, Kwon MC, Song YK, Seong NS, Lee SE, Yi JS, Kwon OW, Lee HY (2006). Effect of aqueous extracts from Rubus coreanus Miquel and Angelica gigas Nakai on anti-tumor and anti-stress activities in mice. Korean Journal of Medicinal Crop Science. 14:206-211 

  22. Kim JH, Lee DH, Lee MH, Jung YH, Park CH, Lee HH, Na CS (2021b). Antioxidant Activity of Asteraceae Plant Seed Extracts. Journal of Life Science. 31(6):543-549 

  23. Kim JM, Shin M (2011). Characteristic of Rubus coreanus Miq. fruits at different ripening stages. Korean Journal of Food Science and Technology. 43:341-347 

  24. Kim JY, Cho JY, Moon JK, Choi GC, Lee KD, Ham KS, Kim SJ (2014). Change of phenylpropanoic acid and flavonol contents at different growth stage of glasswort (Salicornia herbacea L.). Food Science and Biotechnology. 23:685-691 

    원문보기 상세보기

  25. Kim SJ, Kim JY, Baek SH (2011). Effect of composts fermented with Korean medicinal herb wastes on physiological activity of Rubus coreanus Miquel (Bokbunja). Korean Journal of Plant Resources. 24:243-252 

  26. Ku KM, Kim SK, Kang YH (2009). Antioxidant Activity and Functional Components of Corn Silk (Zea mays L.). Korean Journal of Plant Resources. 22(4):323-329 

  27. Kwon YR, Youn KS (2014). Antioxidant activity and physiological properties of Moringa (Moringa oleifera Lam.) leaves extracts with different solvents. Korean Journal of Food Preservation. 21(6):831-837 

  28. Lee GW, Cho YH (2016). Antioxidant Activity of Leaf Extract from Annona muricata. Review of Korea Contents Association. 14(3):43-46 

  29. Lee JE, Kim AJ (2020). Antioxidant Activity, Whitening and Anti-wrinkle Effects of Leaf and Seed Extracts of Brassica juncea L. Czern. Asian Journal of Beauty and Cosmetology. 18(3):283-295 

    상세보기

  30. Lee JW, Do JH (2000). Determination of total phenolic compounds from the fruit of Rubus coreanum and antioxidative activity. Journal of the Korean Society of Food Science and Nutrition. 29:943-947 

  31. Lee MJ, Lee SJ, Choi HR, Lee JH, Jeong JT, Choi KM, Cha JD, Hwang SM, Park JH, Lee JH, Lee TB (2014). Cholesterol improvement effects of co-treatment with black raspberry and red ginseng extracts in mice fed a high cholesterol diet. Journal of the Korean Society of Food Science and Nutrition. 43:1491-1499 

  32. Lee SE, Choi J, Lee JH, Noh HJ, Kim GS, Kim J, Chung HY, Kim SY (2013a). Screening of useful plants with anti-inflammatory and antioxidant activity. Korean Journal of Plant Resources. 26:441-449 

  33. Lee SJ, Lee MJ, Ko YJ, Choi HR, Jeong JT, Choi KM, Cha JD, Hwang SM, Jung HK, Park JH, Lee TB (2013b). Effect of extracts of unripe black raspberry and red ginseng on cholesterol synthesis. Korean Journal of Food Science and Technology. 45:628-635 

  34. Moncada, S. and Higgs, A (1993). The L-arginine-nitric oxide pathway. The New England Journal of Medicine. 329: 2002-2012. 

    상세보기

  35. Nieva Moreno MI, Isla MI, Sampietro AR, Vattuone MA (2000). Comparison of the free radical-scavenging activity of propolis from several regions of Argentina. Journal of Ethnopharmacology. 71(1-2):109-114 

  36. Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evansa C (1999). Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Biology & Medicine. 26(9-10):1231-1237 

  37. Yang HM, Lim YS, Lee YS, Shin HK, Oh YS, Kim JK (2007). Comparision of the anti-inflammatory effects of the extracts from Rubus coreanus and Rubus occidentalis. Korean Journal of Food Science and Technology. 39:342-347 

  38. Yoon I, Wee JH, Moon JH, Ahn TH, Park KH (2003). Isolation and identification of quercetin with antioxidative activity from the fruits of Rubus coreanum Miquel. Korean Journal of Food Science and Technology. 35:499-502 

  39. Yu JS, Yu NJ, Gim SW, Lee SJ, Kwon GT, Yuk HG (2019). Antimicrobial effect of black raspberry (Rubus occidentalis, Bokbunja) extract against Escherichia coli and Staphylococcus aureus. Korean Journal of Food Preservation. 26(3):360-364 

    상세보기

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