[논문]함초의 비만 및 혈중 지질에 미치는 영향에 대한 메타분석

이형선

doi:10.12925/jkocs.2023.40.1.123

함초의 비만 및 혈중 지질에 미치는 영향에 대한 메타분석
Meta-analysis on the Effect of obesity and blood lipid levels in Salicornia herbacea 원문보기

Journal of the Korean Applied Science and Technology = 한국응용과학기술학회지, v.40 no.1, 2023년, pp.123 - 134

이형선 (중원대학교 임상병리학과)

초록
AI-Helper

본 연구는 함초를 섭취한 동물쥐에서 비만과 혈중 지질의 개선 효과에 대한 실험을 체계적 문헌고찰을 통해 통계적으로 분석하였다. 각각의 개별 연구는 PubMed, Embase, RISS, DBpia, NDSL과 같은 데이터베이스로부터 수집되었다. 통계분석을 통해 효과크기를 측정하기 위해 Review Manager 5.3 프로그램이 이용되었고 총 9개의 연구가 최종적으로 포함되었다. 비만유발 흰쥐에서 함초의 섭취는 몸무게를 유의적으로 감소시켰다. 그러나, 식이효율, 간지수와 총콜레스테롤에서 통계적 유의성이 없었다. 또한, 효과크기가 중성지방은 감소하고, 고밀도 콜레스테롤은 증가하였다. 이러한 통계적 분석은 함초가 강력한 항비만과 혈중 지질 개선 효과를 가진다는 결과는 보여준다.

Abstract ▼ AI-Helper

This study presents a meta-analysis research to test the improve effects of obesity and blood lipids on Salicronia herbacea L. (S. herbacea) intake in rats. Individual research materials were selected from database such as PubMed, Embase, RISS, DBpia, and NDSL. The Review Manager 5.3 version was used to estimate effect size through meta-analysis. A total of 9 studies were finally included. Body weight gains were decreased in S. herbacea-treated groups as compared to the high fat diet groups. But, no significant effect was observed on FER, liver index, and total cholesterol. In addition, the effect size of triglyceride was reduced, whereas high density lipoprotein (HDL)-cholesterol was increased in S. herbacea-treated group. In this meta-analysis, the results indicated that S. herbacea have a strong effect on anti-obesity through the blood lipids improvement.

주제어

표/그림 (7)

그림 Fig. 1. PRISMA flow diagram.
그림 Fig. 2. Risk of bias for each included study. (A) Risk of bias summary and (B) graph.
표 Table 1. Characteristics and variable of study
그림 Fig. 3. Forest plots of the effects of S. herbacea effects on (A) body weight gain, (B) FER, and (C) liver index.
그림 Fig. 4. Forest plots of the effect of S. herbacea on (A) total cholesterol, (B) triglyceride, and (C) HDL-cholesterol levels.
그림 Fig. 5. Funnel plots of the effects of S. herbacea on (A) body weight gain, (B) FER, and (C) liver index.
그림 Fig. 6. Funnel plots effect of S. herbacea on (A) total cholesterol, (B) triglyceride, and (C) HDL-cholesterol levels

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표제어: PCR

동의어: Packet Collision Rate

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용어 설명: PCR은 세균 특이성이 있는 primer를 이용하여 적은 수의 세균이 있을지라도 쉽게 검출할 수 있는 유용한 방법이며, 이를 이용하여 구강 내 치면세균막이나 타액에서 직접 세균을 검출할 수 있게 되었다[8].

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