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[해외논문] Affinity-Driven Design of Cargo-Switching Nanoparticles to Leverage a Cholesterol-Rich Microenvironment for Atherosclerosis Therapy 원문보기

ACS nano, v.14 no.6, 2020년, pp.6519 - 6531  

Kim, Heegon ,  Kumar, Sandeep ,  Kang, Dong-Won ,  Jo, Hanjoong ,  Park, Ji-Ho

Abstract AI-Helper 아이콘AI-Helper

Atherosclerotic plaques exhibit high deposition of cholesterol and macrophages. These are not only the main components of the plaques but also key inflammation-triggering sources. However, no existing therapeutics can achieve effective removal of both components within the plaques. Here, we report c...

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참고문헌 (56)

  1. Libby, Peter, Theroux, Pierre. Pathophysiology of Coronary Artery Disease. Circulation, vol.111, no.25, 3481-3488.

  2. Hansson, G철ran K., Libby, Peter. The immune response in atherosclerosis: a double-edged sword. Nature reviews. Immunology, vol.6, no.7, 508-519.

  3. Duewell, Peter, Kono, Hajime, Rayner, Katey J., Sirois, Cherilyn M., Vladimer, Gregory, Bauernfeind, Franz G., Abela, George S., Franchi, Luigi, Nuñez, Gabriel, Schnurr, Max, Espevik, Terje, Lien, Egil, Fitzgerald, Katherine A, Rock, Kenneth L., Moore, Kathryn J., Wright, Samuel D, Hornung, Veit, Latz, Eicke. NLRP3 inflamasomes are required for atherogenesis and activated by cholesterol crystals that form early in disease. Nature, vol.464, no.7293, 1357-1361.

  4. Moore, Kathryn J., Sheedy, Frederick J., Fisher, Edward A.. Macrophages in atherosclerosis: a dynamic balance. Nature reviews. Immunology, vol.13, no.10, 709-721.

  5. Seimon, Tracie, Tabas, Ira. Mechanisms and consequences of macrophage apoptosis in atherosclerosis. Journal of lipid research, vol.50, no.suppl, S382-S387.

  6. Grebe, Alena, Latz, Eicke. Cholesterol Crystals and Inflammation. Current rheumatology reports, vol.15, no.3, 313-.

  7. Samstad, Eivind O., Niyonzima, Nathalie, Nymo, Stig, Aune, Marie H., Ryan, Liv, Bakke, Siril S., Lappegård, Knut T., Brekke, Ole-Lars, Lambris, John D., Damås, Jan K., Latz, Eicke, Mollnes, Tom E., Espevik, Terje. Cholesterol Crystals Induce Complement-Dependent Inflammasome Activation and Cytokine Release. The journal of immunology : official journal of the American Association of Immunologists, vol.192, no.6, 2837-2845.

  8. Yu, X.H., Fu, Y.C., Zhang, D.W., Yin, K., Tang, C.K.. Foam cells in atherosclerosis. Clinica chimica acta, vol.424, 245-252.

  9. Flores, Alyssa M., Ye, Jianqin, Jarr, Kai-Uwe, Hosseini-Nassab, Niloufar, Smith, Bryan R., Leeper, Nicholas J.. Nanoparticle Therapy for Vascular Diseases. Arteriosclerosis, thrombosis, and vascular biology, vol.39, no.4, 635-646.

  10. Chan, Cecilia Ka Wing, Zhang, Lei, Cheng, Chak Kwong, Yang, Hongrong, Huang, Yu, Tian, Xiao Yu, Choi, Chung Hang Jonathan. Recent Advances in Managing Atherosclerosis via Nanomedicine. Small, vol.14, no.4, 1702793-.

  11. Katsuki, Shunsuke, Matoba, Tetsuya, Koga, Jun-ichiro, Nakano, Kaku, Egashira, Kensuke. Anti-inflammatory Nanomedicine for Cardiovascular Disease. Frontiers in cardiovascular medicine, vol.4, 87-.

  12. Gadde, Suresh, Rayner, Katey J.. Nanomedicine Meets microRNA : Current Advances in RNA-Based Nanotherapies for Atherosclerosis. Arteriosclerosis, thrombosis, and vascular biology, vol.36, no.9, e73-e79.

  13. Levine, Glenn N., Keaney Jr., John F., Vita, Joseph A.. Cholesterol Reduction in Cardiovascular Disease - Clinical Benefits and Possible Mechanisms. The New England journal of medicine, vol.332, no.8, 512-521.

  14. Jain, Mukesh K., Ridker, Paul M.. Anti-Inflammatory Effects of Statins: Clinical Evidence and Basic Mechanisms. Nature reviews. Drug discovery, vol.4, no.12, 977-987.

  15. Liao, James K., Laufs, Ulrich. PLEIOTROPIC EFFECTS OF STATINS. Annual review of pharmacology and toxicology, vol.45, 89-118.

  16. Tang, Jun, Lobatto, Mark E., Hassing, Laurien, van der Staay, Susanne, van Rijs, Sarian M., Calcagno, Claudia, Braza, Mounia S., Baxter, Samantha, Fay, Francois, Sanchez-Gaytan, Brenda L., Duivenvoorden, Raphaël, Sager, Hendrik B., Astudillo, Yaritzy M., Leong, Wei, Ramachandran, Sarayu, Storm, Gert, Pérez-Medina, Carlos, Reiner, Thomas, Cormode, David P., Strijkers, Gustav J., Stroes, Erik S. G., Swirski, Filip K., Nahrendorf, Matthias, Fisher, Edward A., Fayad, Zahi A., Mulder, Willem J. M.. Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation. Science advances, vol.1, no.3, e1400223-.

  17. Duivenvoorden, Raphaël, Tang, Jun, Cormode, David P., Mieszawska, Aneta J., Izquierdo-Garcia, David, Ozcan, Canturk, Otten, Maarten J., Zaidi, Neeha, Lobatto, Mark E., van Rijs, Sarian M., Priem, Bram, Kuan, Emma L., Martel, Catherine, Hewing, Bernd, Sager, Hendrik, Nahrendorf, Matthias, Randolph, Gwendalyn J., Stroes, Erik S. G., Fuster, Valentin, Fisher, Edward A., Fayad, Zahi A., Mulder, Willem J. M.. A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation. Nature communications, vol.5, 3065-.

  18. Davis, Mark E., Brewster, Marcus E.. Cyclodextrin-based pharmaceutics: past, present and future. Nature reviews. Drug discovery, vol.3, no.12, 1023-1035.

  19. Choisnard, L., Geze, A., Putaux, J.-L., Wong, Y.-S., Wouessidjewe, D.. Nanoparticles of &bgr;-Cyclodextrin Esters Obtained by Self-Assembling of Biotransesterified &bgr;-Cyclodextrins. Biomacromolecules, vol.7, no.2, 515-520.

  20. Goubet, I., Dahout, C., Semon, E., Guichard, E., Le Quere, J.-L., Voilley, A.. Competitive Binding of Aroma Compounds by &bgr;-Cyclodextrin. Journal of agricultural and food chemistry, vol.49, no.12, 5916-5922.

  21. Zimmer, Sebastian, Grebe, Alena, Bakke, Siril S., Bode, Niklas, Halvorsen, Bente, Ulas, Thomas, Skjelland, Mona, De Nardo, Dominic, Labzin, Larisa I., Kerksiek, Anja, Hempel, Chris, Heneka, Michael T., Hawxhurst, Victoria, Fitzgerald, Michael L., Trebicka, Jonel, Björkhem, Ingemar, Gustafsson, Jan-Åke, Westerterp, Marit, Tall, Alan R., Wright, Samuel D., Espevik, Terje, Schultze, Joachim L., Nickenig, Georg, Lütjohann, Dieter, Latz, Eicke. Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming. Science translational medicine, vol.8, no.333, 333ra50-333ra50.

  22. Crumling, Mark A., King, Kelly A., Duncan, R. Keith. Cyclodextrins and Iatrogenic Hearing Loss: New Drugs with Significant Risk. Frontiers in cellular neuroscience, vol.11, 355-.

  23. Lobatto, Mark E., Fuster, Valentin, Fayad, Zahi A., Mulder, Willem J. M.. Perspectives and opportunities for nanomedicine in the management of atherosclerosis. Nature reviews. Drug discovery, vol.10, no.11, 835-852.

  24. Mulder, Willem J. M., Jaffer, Farouc A., Fayad, Zahi A., Nahrendorf, Matthias. Imaging and Nanomedicine in Inflammatory Atherosclerosis. Science translational medicine, vol.6, no.239, 239sr1-239sr1.

  25. López, Cesar A., de Vries, Alex H., Marrink, Siewert J.. Molecular Mechanism of Cyclodextrin Mediated Cholesterol Extraction. PLoS computational biology, vol.7, no.3, e1002020-.

  26. Süle, András, Szente, Lajos, Csempesz, Ferenc. Enhancement of drug solubility in supramolecular and colloidal systems. Journal of pharmaceutical sciences : a publication of the American Pharmaceutical Association, vol.98, no.2, 484-494.

  27. Davidson, Cristin D., Fishman, Yonatan I., Puskás, István, Szemán, Julianna, Sohajda, Tamás, McCauliff, Leslie A., Sikora, Jakub, Storch, Judith, Vanier, Marie T., Szente, Lajos, Walkley, Steven U., Dobrenis, Kostantin. Efficacy and ototoxicity of different cyclodextrins in Niemann–Pick C disease. Annals of clinical and translational neurology, vol.3, no.5, 366-380.

  28. Csempesz, F., Sule, A., Puskas, I.. Induced surface activity of supramolecular cyclodextrinstatin complexes: Relevance in drug delivery. Colloids and surfaces. A, Physicochemical and engineering aspects, vol.354, no.1, 308-313.

  29. Akbarzadeh, Abolfazl, Rezaei-Sadabady, Rogaie, Davaran, Soodabeh, Joo, Sang Woo, Zarghami, Nosratollah, Hanifehpour, Younes, Samiei, Mohammad, Kouhi, Mohammad, Nejati-Koshki, Kazem. Liposome: classification, preparation, and applications. Nanoscale research letters, vol.8, no.1, 102-102.

  30. Ulrich, A.S., Sami, M., Watts, A.. Hydration of DOPC bilayers by differential scanning calorimetry. Biochimica et biophysica acta, Biomembranes, vol.1191, no.1, 225-230.

  31. Chen, Jun, Cheng, Dong, Li, Jun, Wang, Yong, Guo, Jian-xin, Chen, Zhi-peng, Cai, Bao-chang, Yang, Tao. Influence of lipid composition on the phase transition temperature of liposomes composed of both DPPC and HSPC. Drug development and industrial pharmacy, vol.39, no.2, 197-204.

  32. Brown, Anna, Patel, Siddharth, Ward, Carl, Lorenz, Anna, Ortiz, Mauren, DuRoss, Allison, Wieghardt, Fabian, Esch, Amanda, Otten, Elsje G., Heiser, Laura M., Korolchuk, Viktor I., Sun, Conroy, Sarkar, Sovan, Sahay, Gaurav. PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder. Scientific reports, vol.6, 31750-.

  33. Atger, V M, de la Llera Moya, M, Stoudt, G W, Rodrigueza, W V, Phillips, M C, Rothblat, G H. Cyclodextrins as catalysts for the removal of cholesterol from macrophage foam cells.. The Journal of clinical investigation, vol.99, no.4, 773-780.

  34. Miller, C. R., Bondurant, B., McLean, S. D., McGovern, K. A., O'Brien, D. F.. Liposome−Cell Interactions in Vitro: Effect of Liposome Surface Charge on the Binding and Endocytosis of Conventional and Sterically Stabilized Liposomes. Biochemistry, vol.37, no.37, 12875-12883.

  35. Moore, Kathryn J., Sheedy, Frederick J., Fisher, Edward A.. Macrophages in atherosclerosis: a dynamic balance. Nature reviews. Immunology, vol.13, no.10, 709-721.

  36. Bagalkot, Vaishali, Badgeley, Marcus A., Kampfrath, Thomas, Deiuliis, Jeffrey A., Rajagopalan, Sanjay, Maiseyeu, Andrei. Hybrid nanoparticles improve targeting to inflammatory macrophages through phagocytic signals. Journal of controlled release : official journal of the Controlled Release Society, vol.217, 243-255.

  37. Rajamäki, Kristiina, Lappalainen, Jani, Öörni, Katariina, Välimäki, Elina, Matikainen, Sampsa, Kovanen, Petri T., Eklund, Kari K.. Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation. PloS one, vol.5, no.7, e11765-.

  38. Zolberg Relevy, Noa, Bechor, Sapir, Harari, Ayelet, Ben-Amotz, Ami, Kamari, Yehuda, Harats, Dror, Shaish, Aviv. The Inhibition of Macrophage Foam Cell Formation by 9-Cis β-Carotene Is Driven by BCMO1 Activity. PloS one, vol.10, no.1, e0115272-.

  39. Grosse, Pierre Yves, Bressolle, Françoise, Rouanet, Philippe, Joulia, Jean Michel, Pinguet, Frédéric. Methyl-β-cyclodextrin and doxorubicin pharmacokinetics and tissue concentrations following bolus injection of these drugs alone or together in the rabbit. International journal of pharmaceutics, vol.180, no.2, 215-223.

  40. Schachter, Michael. Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update. Fundamental & clinical pharmacology, vol.19, no.1, 117-125.

  41. Nam, Douglas, Ni, Chih-Wen, Rezvan, Amir, Suo, Jin, Budzyn, Klaudia, Llanos, Alexander, Harrison, David, Giddens, Don, Jo, Hanjoong. Partial carotid ligation is a model of acutely induced disturbed flow, leading to rapid endothelial dysfunction and atherosclerosis. American journal of physiology, Heart and circulatory physiology, vol.297, no.4, H1535-H1543.

  42. Jo, H., Son, D., Kumar, S.. The atypical mechanosensitive microrna-712 derived from pre-ribosomal RNA induces endothelial inflammation and atherosclerosis. Atherosclerosis, vol.235, no.2, e40-e41.

  43. Sparrow, Carl P., Burton, Charlotte A., Hernandez, Melba, Mundt, Steven, Hassing, Heide, Patel, Sushma, Rosa, Ray, Hermanowski-Vosatka, Anne, Wang, Pei-Ran, Zhang, Donghui, Peterson, Larry, Detmers, Patricia A., Chao, Yu-Sheng, Wright, Samuel D.. Simvastatin Has Anti-Inflammatory and Antiatherosclerotic Activities Independent of Plasma Cholesterol Lowering. Arteriosclerosis, thrombosis, and vascular biology, vol.21, no.1, 115-121.

  44. Plump, A.S., Smith, J.D., Hayek, T., Aalto-Setala, K., Walsh, A., Verstuyft, J.G., Rubin, E.M., Breslow, J.L.. Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell, vol.71, no.2, 343-353.

  45. Bergstrom, James D, Bostedor, Richard G, Rew, Deborah J, Geissler, Wayne M, Wright, Samuel D, Chao, Yu-Sheng. Hepatic responses to inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase: a comparison of atorvastatin and simvastatin. Biochimica et biophysica acta, Lipids and lipid metabolism, vol.1389, no.3, 213-221.

  46. Yamauchi, S., Linscheer, W. G., Beach, D. H.. Increase in serum and bile cholesterol and HMG-CoA reductase by lovastatin in rats. American journal of physiology, Gastrointestinal and liver physiology, vol.260, no.4, G625-G630.

  47. Reihnér, Eva, Rudling, Mats, Ståhlberg, Dagny, Berglund, Lars, Ewerth, Staffan, Björkhem, Ingemar, Einarsson, Kurt, Angelin, Bo. Influence of Pravastatin, a Specific Inhibitor of HMG-CoA Reductase, on Hepatic Metabolism of Cholesterol. The New England journal of medicine, vol.323, no.4, 224-228.

  48. Schonewille, Marleen, Freark de Boer, Jan, Mele, Laura, Wolters, Henk, Bloks, Vincent W., Wolters, Justina C., Kuivenhoven, Jan A., Tietge, Uwe J. F., Brufau, Gemma, Groen, Albert K.. Statins increase hepatic cholesterol synthesis and stimulate fecal cholesterol elimination in mice. Journal of lipid research, vol.57, no.8, 1455-1464.

  49. Du, Jinzhi, Lane, Lucas A., Nie, Shuming. Stimuli-responsive nanoparticles for targeting the tumor microenvironment. Journal of controlled release : official journal of the Controlled Release Society, vol.219, 205-214.

  50. Uthaman, Saji, Huh, Kang Moo, Park, In-Kyu. Tumor microenvironment-responsive nanoparticles for cancer theragnostic applications. Biomaterials research, vol.22, no.1, 22-.

  51. Irie, Tetsumi, Fukunaga, Kazuhiro, Garwood, Marcia K., Carpenter, Thomas O., Pitha, Jan, Pitha, Josef. Hydroxypropylcyclodextrins in Parenteral Use. II: Effects on Transport and Disposition of Lipids in Rabbit and Humans. Journal of pharmaceutical sciences : a publication of the American Pharmaceutical Association, vol.81, no.6, 524-528.

  52. Jun, Seoung Wook, Kim, Min-Soo, Kim, Jeong-Soo, Park, Hee Jun, Lee, Sibeum, Woo, Jong-Soo, Hwang, Sung-Joo. Preparation and characterization of simvastatin/hydroxypropyl-β-cyclodextrin inclusion complex using supercritical antisolvent (SAS) process. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V, vol.66, no.3, 413-421.

  53. Rosenbaum, Anton I., Zhang, Guangtao, Warren, J. David, Maxfield, Frederick R.. Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells. Proceedings of the National Academy of Sciences of the United States of America, vol.107, no.12, 5477-5482.

  54. J. Lipid Res. Christian A. E. 1475 40 1999 10.1016/S0022-2275(20)33390-3 

  55. Tanaka, Yuta, Yamada, Yusei, Ishitsuka, Yoichi, Matsuo, Muneaki, Shiraishi, Koki, Wada, Koki, Uchio, Yushiro, Kondo, Yuki, Takeo, Toru, Nakagata, Naomi, Higashi, Taishi, Motoyama, Keiichi, Arima, Hidetoshi, Mochinaga, Sakiko, Higaki, Katsumi, Ohno, Kousaku, Irie, Tetsumi. Efficacy of 2-Hydroxypropyl-β-cyclodextrin in Niemann-Pick Disease Type C Model Mice and Its Pharmacokinetic Analysis in a Patient with the Disease. Biological & pharmaceutical bulletin, vol.38, no.6, 844-851.

  56. Cantuti-Castelvetri, Ludovico, Fitzner, Dirk, Bosch-Queralt, Mar, Weil, Marie-Theres, Su, Minhui, Sen, Paromita, Ruhwedel, Torben, Mitkovski, Miso, Trendelenburg, George, Lutjohann, Dieter, Mobius, Wiebke, Simons, Mikael. Defective cholesterol clearance limits remyelination in the aged central nervous system. Science, vol.359, no.6376, 684-688.

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